Výsledky vyhledávání - "M. K. Kemelo"

Sirtuin-activating compounds (STACs) alleviate D-galactosamine/lipopolysaccharide-induced hepatotoxicity in rats: involvement of sirtuin 1 and heme oxygenase 1

Autor: N Kutinová Canová, M. K. Kemelo, A Horinek, Hassan Farghali

Publikováno v: Physiological research. 66(3)

Sirtuin activating compounds (STACs) attenuate various type of liver insults through mechanisms which are not fully understood. In the present study, we investigated the ameliorative potential of quercetin (natural polyphenol) and SRT1720 (synthetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4fc93d9bcb2824476511a18b8294d4
https://pubmed.ncbi.nlm.nih.gov/28248534

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D-galactosamine/lipopolysaccharide-induced hepatotoxicity downregulates sirtuin 1 in rat liver: Role of sirtuin 1 modulation in hepatoprotection

Autor: M. K. Kemelo, Hassan Farghali, N Kutinová Canová, L Wojnarová

Publikováno v: Scopus-Elsevier
ResearcherID
Europe PubMed Central

D-Galactosamine/Lipopolysaccharide (D-GalN/LPS) is a well known model of hepatotoxicity that closely resembles acute liver failure (ALF) seen clinically. The role of sirtuin 1 in this model has not yet been documented. However, there have been a numb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7500cb3646239b9d09bdb4ea6faae39a
http://www.scopus.com/inward/record.url?eid=2-s2.0-84920008183&partnerID=MN8TOARS

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