Zobrazeno 1 - 6
of 6
pro vyhledávání: '"M. Joshua Cody"'
Autor:
Sergio A. Lira, Karen Thomas, M. Joshua Cody, Stefanie N. Vogel, Masayuki Fukata, Louis J. DeTolla, Karen M. Kopydlowski, Aiping Zhao, Terez Shea-Donohue
Publikováno v:
Innate Immunity. 14:117-124
The role of TLRs and MyD88 in the maintenance of gut integrity in response to dextran sodium sulfate (DSS)-induced colitis was demonstrated recently and led to the conclusion that the innate immune response to luminal commensal flora provides necessa
Autor:
Jennifer Major, Bryan W. Jones, M. Joshua Cody, Bryan R.G. Williams, Thomas A. Hamilton, Matthew J. Fenton, Shuling Zhang, Stefanie N. Vogel, Pin-Yu Perera, Vladimir Y. Toshchakov, Karen Thomas
Publikováno v:
Nature Immunology. 3:392-398
Toll-like receptor 2 (TLR2) agonists induce a subset of TLR4-inducible proinflammatory genes, which suggests the use of differential signaling pathways. Murine macrophages stimulated with the TLR4 agonist Escherichia coli lipopolysaccharide (LPS), bu
Autor:
Cindy A. Salkowski, Karen Kopydlowski, Jorge Blanco, M. Joshua Cody, Ranney McNally, Stefanie N. Vogel
Publikováno v:
The Journal of Immunology. 163:1529-1536
Macrophages derived from IFN-regulatory factor-1 (IRF-1) and IRF-2 knockout (−/−) and wild-type (+/+) mice were utilized to examine the role of these transcription factors in the regulation of IL-12 mRNA and protein expression. Induction of IL-12
Autor:
Aristóbolo M. Silva, Arnd Lentschat, Bryan R.G. Williams, Vladimir Y. Toshchakov, Thomas A. Hamilton, Matthew J. Fenton, Jeniffer Major, Shuling Zhang, Stefanie N. Vogel, Pin Yu Perera, Bryan W. Jones, Karen E. Thomas, M. Joshua Cody
Publikováno v:
Journal of endotoxin research. 9(3)
That TLRs share a common MyD88-dependent signaling pathway which results in the generation of nuclear DNA-binding proteins, such as NF-κB, is a well-accepted paradigm. However, studies from our laboratories and others suggested that TLR4 agonists el
Autor:
Vladimir, Toshchakov, Bryan W, Jones, Pin-Yu, Perera, Karen, Thomas, M Joshua, Cody, Shuling, Zhang, Bryan R G, Williams, Jennifer, Major, Thomas A, Hamilton, Matthew J, Fenton, Stefanie N, Vogel
Publikováno v:
Nature immunology. 3(4)
Toll-like receptor 2 (TLR2) agonists induce a subset of TLR4-inducible proinflammatory genes, which suggests the use of differential signaling pathways. Murine macrophages stimulated with the TLR4 agonist Escherichia coli lipopolysaccharide (LPS), bu
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 165(7)
Mice with a targeted mutation in the gene that encodes the transcription factor IFN regulatory factor-1 (IRF-1) were used to assess the contribution of IRF-1 to IL-12-dependent and IL-12-independent pathways of IFN-γ production. In response to LPS,