Zobrazeno 1 - 9
of 9
pro vyhledávání: '"M. Jose Perez-Garcia"'
Autor:
Alba Sansa, Ivan Hidalgo, Maria P. Miralles, Sandra de la Fuente, M. Jose Perez-Garcia, Francina Munell, Rosa M. Soler, Ana Garcera
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-15 (2021)
Abstract Spinal muscular atrophy (SMA) is a neuromuscular genetic disease caused by reduced survival motor neuron (SMN) protein. SMN is ubiquitous and deficient levels cause spinal cord motoneurons (MNs) degeneration and muscle atrophy. Nevertheless,
Externí odkaz:
https://doaj.org/article/6519b01e036441a5a70343d791779e8b
Autor:
Kong-Peng Lam, Cristina Hernández, Agustín Ruíz Lasa, Joan X. Comella, Joaquín López-Soriano, Jianxin Huo, Patricia Bogdanov, M. Jose Perez-Garcia, Hugo Ramos, Anna Sirés, Rafael Simó, Shengli Xu, Montse Solé, Mireia Turch-Anguera, Joel Sampedro
Publikováno v:
Journal of neuroscience researchREFERENCES. 99(12)
Fas Apoptotic Inhibitory Molecule protein (FAIM) is a death receptor antagonist and an apoptosis regulator. It encodes two isoforms, namely FAIM-S (short) and FAIM-L (long), both with significant neuronal functions. FAIM-S, which is ubiquitously expr
Autor:
Joan X. Comella, Yolanda de Pablo, M. Jose Perez-Garcia, Valentín Ceña, Marta Llovera, Rosa M. Soler
Publikováno v:
Journal of Biological Chemistry. 279:6132-6142
Moderate increases of intracellular Ca2+ concentration ([Ca2+]i), induced by either the activation of tropomyosin receptor kinase (Trk) receptors for neurotrophins or by neuronal activity, regulate different intracellular pathways and neuronal surviv
Autor:
Joan X. Comella, Marta Llovera, Niclas Lindqvist, Maya V. Georgieva, M. Jose Perez-Garcia, Yolanda de Pablo, Daniel Sanchis, Rosa M. Soler
Publikováno v:
Journal of neurochemistry. 104(1)
Tropomyosin-related kinase A (TrkA) receptor mediates the effects exerted by nerve growth factor on several subpopulations of neuronal cells. Ligand binding to TrkA induces receptor autophosphorylation on several tyrosine residues and the activation
Autor:
Joan X. Comella, Marta Llovera, Myriam Gou-Fabregas, Yolanda de Pablo, M. Jose Perez-Garcia, Rosa M. Soler
Publikováno v:
Repositorio Abierto de la UdL
Universitad de Lleida
Recercat. Dipósit de la Recerca de Catalunya
instname
Universitad de Lleida
Recercat. Dipósit de la Recerca de Catalunya
instname
Neurotrophic factors promote motoneuron (MN) survival through increased intracellular calcium (Ca(2+)) and regulation of the phosphatidylinositol (PI) 3-kinase/protein kinase B (PKB) pathway by calmodulin (CaM). Activation of the PI 3-kinase/PKB path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a2865b788075dbdd88820edab1857b
https://hdl.handle.net/10459.1/59314
https://hdl.handle.net/10459.1/59314
Autor:
Jisheng Zhang, Stephanie Reix, Ramon Trullas, Rana S. Moubarak, Victor J. Yuste, Carme Solé, Victoria Iglesias-Guimarais, Nuria Llecha, M. Jose Perez-Garcia, Raffaella Gozzelino, Miguel F. Segura, Nahuai Badiola, José Rodríguez-Alvarez, Joan X. Comella, Daniel Sanchis
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat. Dipósit de la Recerca de Catalunya
Upon activation, tumor necrosis factor alpha (TNF-α) receptor can engage apoptotic or survival pathways. Inhibition of macromolecular synthesis is known to sensitize cells to TNF-α-induced cell death. It is believed that this sensitization is due t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a12659b99b3143b15136d8f11077ae8
http://hdl.handle.net/10261/32375
http://hdl.handle.net/10261/32375
Autor:
Elena Coccia, Marc Masanas, Joaquín López-Soriano, Miguel F. Segura, Joan X. Comella, M. José Pérez-García
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Apoptosis plays an important role during development, control of tissue homeostasis and in pathological contexts. Apoptosis is executed mainly through the intrinsic pathway or the death receptor pathway, i.e., extrinsic pathway. These processes are t
Externí odkaz:
https://doaj.org/article/22262f9d75ec45029fff23ba8273fc5d
Publikováno v:
Biomedicines, Vol 9, Iss 10, p 1365 (2021)
Gait impairments in Alzheimer’s disease (AD) result from structural and functional deficiencies that generate limitations in the performance of activities and restrictions in individual’s biopsychosocial participation. In a translational way, we
Externí odkaz:
https://doaj.org/article/291c7cf0e1ae4983b47f363492044717
Autor:
Nahuai Badiola, Marta Pascual, Raffaella Gozzelino, Rana S. Moubarak, Victor J. Yuste, Joan X. Comella, Carme Solé, Eduardo Soriano, Nuria Llecha, Miguel F. Segura, José Rodríguez-Alvarez, M. Jose Perez-Garcia, Victoria Iglesias, Jose R. Bayascas
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Repositorio Abierto de la UdL
Universitad de Lleida
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Repositorio Abierto de la UdL
Universitad de Lleida
Death receptors (DRs) and their ligands are expressed in developing nervous system. However, neurons are generally resistant to death induction through DRs and rather their activation promotes neuronal outgrowth and branching. These results suppose t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::910ef4b1638d35baa442c9ec4c55fafb
http://hdl.handle.net/10459.1/60401
http://hdl.handle.net/10459.1/60401