Zobrazeno 1 - 10
of 698
pro vyhledávání: '"M. Johannsen"'
IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP
Autor:
K. L. Jønsson, A. Laustsen, C. Krapp, K. A. Skipper, K. Thavachelvam, D. Hotter, J. H. Egedal, M. Kjolby, P. Mohammadi, T. Prabakaran, L. K. Sørensen, C. Sun, S. B. Jensen, C. K. Holm, R. J. Lebbink, M. Johannsen, M. Nyegaard, J. G. Mikkelsen, F. Kirchhoff, S. R. Paludan, M. R. Jakobsen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
The role of IFI16 as a DNA sensor is highly controversial. With support from a Nature Communications back-to-back publication from Almineet al. the authors here provide functional evidence that IFI16 is required for DNA sensing via the cGAS-STING pat
Externí odkaz:
https://doaj.org/article/f077d067175040ebb442e5ac090773d6
Blood and MRI biomarkers of mild traumatic brain injury in non-concussed collegiate football players
Autor:
Eunhan Cho, Joshua Granger, Bailey Theall, Nathan Lemoine, Derek Calvert, Jack Marucci, Shelly Mullenix, Hollis O’Neal, Tomas Jacome, Brian A. Irving, Neil M. Johannsen, Owen Carmichael, Guillaume Spielmann
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Football has one of the highest incidence rates of mild traumatic brain injury (mTBI) among contact sports; however, the effects of repeated sub-concussive head impacts on brain structure and function remain under-studied. We assessed the as
Externí odkaz:
https://doaj.org/article/d6fa386318fd4fb0802a350346eee255
Autor:
Brett H. Davis, James E. Stampley, Joshua Granger, Matthew C. Scott, Timothy D. Allerton, Neil M. Johannsen, Guillaume Spielmann, Brian A. Irving
Publikováno v:
Physiological Reports, Vol 12, Iss 12, Pp n/a-n/a (2024)
Abstract Low‐load resistance exercise (LLRE) to failure can increase muscle mass, strength, endurance, and mitochondrial oxidative capacity (OXPHOS). However, the impact of adding blood flow restriction to low‐load resistance exercise (LLBFR) whe
Externí odkaz:
https://doaj.org/article/0f8081c7fc7c4cb1bd6d0778384f222e
Autor:
Youyoung Kim, John P. Campbell, Neil M. Johannsen, Timothy S. Church, Eunhan Cho, Jennifer Heaney, Guillaume Spielmann
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Background and aims: Serum polyclonal free light chains (FLCs) levels are associated with overall survival in the general population, reflecting their utility as a biomarker of underlying immune activation and inflammation. Regular exercise is known
Externí odkaz:
https://doaj.org/article/236081f3d9d64ebb843c402fb3edfe6d
Autor:
Haoyan Wang, Bailey M. Theall, Kate S. Early, Cullen Vincellette, Lyle Robelot, Rick L. Sharp, Jack Marucci, Shelly Mullenix, Derek Calvert, Nathan P. Lemoine, Brain A. Irving, Guillaume Spielmann, Neil M. Johannsen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract To investigate the seasonal changes in physiological and psychological parameters of stress in collegiate swimmers. Fifteen NCAA Division I swimmers (8 men) participated in a tethered anaerobic swim test to determine physiological responses
Externí odkaz:
https://doaj.org/article/072660d7309a4b11b09a3e42f5a5115b
Autor:
Liz Simon, Stefany D. Primeaux, Danielle E. Levitt, Brianna Bourgeois, Neil M. Johannsen, Adrianna Peters, Jameel Ahmed, Richard H. Marshall, Alexandra H. Fairchild, Tekeda F. Ferguson, Patricia E. Molina
Publikováno v:
AIDS Research and Therapy, Vol 20, Iss 1, Pp 1-11 (2023)
Abstract Background Effective antiretroviral therapy (ART) in people living with HIV (PLWH) has improved life expectancy and increased risk of age-associated cardiometabolic comorbidities. At-risk alcohol use is more frequent among PLWH and increases
Externí odkaz:
https://doaj.org/article/5409df49ae2e45a7bb67604574bf6b5f
Autor:
James E. Stampley, Eunhan Cho, Haoyan Wang, Bailey Theall, Neil M. Johannsen, Guillaume Spielmann, Brian A. Irving
Publikováno v:
Physiological Reports, Vol 11, Iss 11, Pp n/a-n/a (2023)
Abstract Acute aerobic exercise increases the number and proportions of circulating peripheral blood mononuclear cells (PMBC) and can alter PBMC mitochondrial bioenergetics. In this study, we aimed to examine the impact of a maximal exercise bout on
Externí odkaz:
https://doaj.org/article/ff397b75a3ff4e9c8456745c221cd00f
Autor:
Alyssa N. Varanoske, Melissa N. Harris, Callie Hebert, Neil M. Johannsen, Steven B. Heymsfield, Frank L. Greenway, Arny A. Ferrando, Jennifer C. Rood, Stefan M. Pasiakos
Publikováno v:
Physiological Reports, Vol 11, Iss 6, Pp n/a-n/a (2023)
Abstract Physical performance decrements observed during multi‐stressor military operations may be attributed, in part, to cellular membrane dysfunction, which is quantifiable using phase angle (PhA) derived from bioelectrical impedance analysis (B
Externí odkaz:
https://doaj.org/article/f73ded67045b44e6a95baa6e50688daf
Autor:
S. Nicole Fearnbach, Corby K. Martin, Steven B. Heymsfield, Amanda E. Staiano, Robert L. Newton, Alex C. Garn, Neil M. Johannsen, Daniel S. Hsia, Owen T. Carmichael, Sreekrishna Ramakrishnapillai, Kori B. Murray, John E. Blundell, Graham Finlayson
Publikováno v:
International Journal of Behavioral Nutrition and Physical Activity, Vol 17, Iss 1, Pp 1-13 (2020)
Abstract Background High levels of sedentary behavior and low physical activity are associated with poor health, and the cognitive determinants of these behaviors in children and adolescents are not well understood. To address this gap, we developed
Externí odkaz:
https://doaj.org/article/c5b37542f73043579b8bf8692eb022d3
Autor:
Stefan M. Pasiakos, Claire E. Berryman, J. Philip Karl, Harris R. Lieberman, Jeb S. Orr, Lee M. Margolis, John A. Caldwell, Andrew J. Young, Monty A. Montano, William J. Evans, Oshin Vartanian, Owen T. Carmichael, Kishore M. Gadde, Neil M. Johannsen, Robbie A. Beyl, Melissa N. Harris, Jennifer C. Rood
Publikováno v:
EBioMedicine, Vol 46, Iss , Pp 411-422 (2019)
Background: Severe energy deficits during military operations, produced by significant increases in exercise and limited dietary intake, result in conditions that degrade lean body mass and lower-body muscle function, which may be mediated by concomi
Externí odkaz:
https://doaj.org/article/6c5247c2064c4917b538e38e4f07ace6