Zobrazeno 1 - 10
of 673
pro vyhledávání: '"M. Jeffries"'
Autor:
Thaïs A. Bernos, Zdenek Lajbner, Petr Kotlík, Jacklyn M. Hill, Silvia Marková, Jonah Yick, Nicholas E. Mandrak, Ken M. Jeffries
Publikováno v:
Evolutionary Applications, Vol 17, Iss 10, Pp n/a-n/a (2024)
ABSTRACT Species invading non‐native habitats can cause irreversible environmental damage and economic harm. Yet, how introduced species become widespread invaders remains poorly understood. Adaptation within native‐range habitats and rapid adapt
Externí odkaz:
https://doaj.org/article/ef137051f4e94b0695e1777ba32bdd98
Autor:
Madeleine Starks, Christina M. Schaefer, Kenneth M. Jeffries, David Deslauriers, Kim Hoang Luong, Charles S. Wong, Mark L. Hanson, Charles W. Knapp
Publikováno v:
Arctic Science, Vol 9, Iss 4, Pp 919-927 (2023)
Antibiotic resistance (AR) is a growing health concern worldwide and the Arctic represents an understudied region in terms of AR. This study aimed to quantify AR genes (ARGs) from effluent released from a wastewater treatment plant (WWTP) in Iqaluit,
Externí odkaz:
https://doaj.org/article/6b738ef495f9405aa5d85718bf46e4f7
Autor:
Clement E. Blanchet, Adam Round, Haydyn D. T. Mertens, Kartik Ayyer, Melissa Graewert, Salah Awel, Daniel Franke, Katerina Dörner, Saša Bajt, Richard Bean, Tânia F. Custódio, Raphael de Wijn, E. Juncheng, Alessandra Henkel, Andrey Gruzinov, Cy M. Jeffries, Yoonhee Kim, Henry Kirkwood, Marco Kloos, Juraj Knoška, Jayanath Koliyadu, Romain Letrun, Christian Löw, Jana Makroczyova, Abhishek Mall, Rob Meijers, Gisel Esperanza Pena Murillo, Dominik Oberthür, Ekaterina Round, Carolin Seuring, Marcin Sikorski, Patrik Vagovic, Joana Valerio, Tamme Wollweber, Yulong Zhuang, Joachim Schulz, Heinrich Haas, Henry N. Chapman, Adrian P. Mancuso, Dmitri Svergun
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Free-electron lasers (FEL) are revolutionizing X-ray-based structural biology methods. While protein crystallography is already routinely performed at FELs, Small Angle X-ray Scattering (SAXS) studies of biological macromolecules are not as
Externí odkaz:
https://doaj.org/article/bcf514c39af3436883cc2c8e5bf81aab
Autor:
Benedikt Goretzki, Christoph Wiedemann, Brett A. McCray, Stefan L. Schäfer, Jasmin Jansen, Frederike Tebbe, Sarah-Ana Mitrovic, Julia Nöth, Ainara Claveras Cabezudo, Jack K. Donohue, Cy M. Jeffries, Wieland Steinchen, Florian Stengel, Charlotte J. Sumner, Gerhard Hummer, Ute A. Hellmich
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Intrinsically disordered regions (IDRs) are essential for membrane receptor regulation but often remain unresolved in structural studies. TRPV4, a member of the TRP vanilloid channel family involved in thermo- and osmosensation, has a large
Externí odkaz:
https://doaj.org/article/164d0c141a984b619e153ae313a859dd
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The nucleocapsid protein (N) of SARS-CoV-2 plays a pivotal role during the viral life cycle. It is involved in RNA transcription and accounts for packaging of the large genome into virus particles. N manages the enigmatic balance of bulk RNA
Externí odkaz:
https://doaj.org/article/4b4a5f33653b4e0abb207b71ca843e18
Autor:
Jenny Lai, Didem Demirbas, Junho Kim, Ailsa M. Jeffries, Allie Tolles, Junseok Park, Thomas W. Chittenden, Patrick G. Buckley, Timothy W. Yu, Michael A. Lodato, Eunjung Alice Lee
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113622- (2024)
Summary: While ATM loss of function has long been identified as the genetic cause of ataxia-telangiectasia (A-T), how it leads to selective and progressive degeneration of cerebellar Purkinje and granule neurons remains unclear. ATM expression is enr
Externí odkaz:
https://doaj.org/article/bb2b0c8299d2444ab13e02b7f0a6bb28
Publikováno v:
FACETS, Vol 8, Iss , Pp 1-15 (2023)
Lake Winnipeg, Manitoba, is Canada’s second largest commercial inland freshwater fishery, and concern over collapse of the walleye fishery is growing. Molecular techniques have been increasingly used to study responses of wild organisms to environm
Externí odkaz:
https://doaj.org/article/7e4af94363e54abc8f9ef7b0adf7c1b5
Autor:
Thaïs A. Bernos, Sunčica Avlijaš, Jaclyn Hill, Olivier Morissette, Anthony Ricciardi, Nicholas E. Mandrak, Kenneth M. Jeffries
Publikováno v:
Evolutionary Applications, Vol 16, Iss 1, Pp 173-188 (2023)
Abstract Introduced and geographically expanding populations experience similar eco‐evolutionary challenges, including founder events, genetic bottlenecks, and novel environments. Theory predicts that reduced genetic diversity resulting from such p
Externí odkaz:
https://doaj.org/article/2515d539be6e44ab9d7e2fe957c6f2e4
Autor:
Junho Kim, August Yue Huang, Shelby L. Johnson, Jenny Lai, Laura Isacco, Ailsa M. Jeffries, Michael B. Miller, Michael A. Lodato, Christopher A. Walsh, Eunjung Alice Lee
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
DNA damage has been implicated in aging and neurodegeneration. Here, the authors develop a bioinformatic method to detect deletions in single neuron genome sequences and reveal an increased burden of somatic deletions during aging and in DNA repair d
Externí odkaz:
https://doaj.org/article/162ddeb312a542bf86be9477a455f1cc
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-13 (2022)
Abstract Background The mechanisms by which glia respond to viral central nervous system (CNS) pathogens are now becoming apparent with the demonstration that microglia and astrocytes express an array of pattern recognition receptors that include int
Externí odkaz:
https://doaj.org/article/00db76a18b774454ab857048c200cbdf