Zobrazeno 1 - 10
of 14
pro vyhledávání: '"M. Jamie T.V. Cope"'
Autor:
M. Jamie T.V. Cope, Lawrence Lee, Faleh Salaymeh, Stephen D. Harrison, Lance Berman, Jerry M. Buysse, Craig Park, Wade W. Benton, Lingyun Li, Deidre Madsen
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics
Hyperkalemia is a potentially life-threatening condition, and patients who have chronic kidney disease, who are diabetic, or who are taking renin–angiotensin–aldosterone system inhibitors are at increased risk. Therapeutic options for hyperkalemi
Autor:
Mara C. Duncan, Adam C. Martin, Yidi Sun, M. Jamie T.V. Cope, David G. Drubin, Kensaku Mizuno, Junko Toshima, Scott Anderson, John R. Yates, Jiro Toshima
Publikováno v:
Molecular Biology of the Cell. 18:658-668
Control of actin assembly nucleated by the Arp2/3 complex plays a crucial role during budding yeast endocytosis. The yeast Eps15-related Arp2/3 complex activator, Pan1p, is essential for endocytic internalization and proper actin organization. Pan1p
Autor:
David G. Drubin, Silvia Ferracuti, Matthias Wilmanns, Katja Schirwitz, Adriana Zucconi, Barbara Fazi, Luisa Castagnoli, Gianni Cesareni, Alice Douangamath, M. Jamie T.V. Cope
Publikováno v:
Journal of Biological Chemistry. 277:5290-5298
Abp1p is an actin-binding protein that plays a central role in the organization of Saccharomyces cerevisiae actin cytoskeleton. By a combination of two-hybrid and phage-display approaches, we have identified six new ligands of the Abp1-SH3 domain. No
Publikováno v:
Nature Cell Biology. 3:687-690
Longstanding evidence supports a role for actin in endocytosis; an intact actin cytoskeleton is required for endocytosis in yeast, and drugs that inhibit actin polymerization inhibit endocytosis in both yeast and mammalian cells. The yeast Arp2/3 com
Publikováno v:
Plant Physiology. 125:360-368
We have previously shown that the wheat (Triticum aestivum) TaADF gene expression level is correlated with the plants capacity to tolerate freezing. Sequence analysis revealed that this gene encodes a protein homologous to members of the actin-depoly
Publikováno v:
The Journal of Cell Biology
Ark1p (actin regulating kinase 1) was identified as a yeast protein that binds to Sla2p, an evolutionarily conserved cortical actin cytoskeleton protein. Ark1p and a second yeast protein, Prk1p, contain NH2-terminal kinase domains that are 70% identi
Publikováno v:
Structure. 4:969-987
Background Myosins are motors that use energy supplied by ATP to travel along actin filaments. The structure of myosin is known, but the actin-binding site is not well defined, and the mechanisms by which actin activates ATP hydrolysis by myosin, and
Autor:
Kenneth R. Henry, David A. Nix, Clarence S.M. Chan, Ji Suk Chang, Sandra K. Lemmon, David G. Drubin, M. Jamie T.V. Cope, Kathleen D'Hondt
Publikováno v:
Current biology : CB. 13(17)
Endocytosis is a dynamic process requiring a network of interacting proteins that assemble and disassemble during cargo capture and vesicle formation. A major mechanism for regulation of this process involves the reversible phosphorylation of endocyt
Autor:
Mariko Sekiya-Kawasaki, M. Jamie T.V. Cope, Beverly Wendland, David G. Drubin, Chao Zhang, Kevan M. Shokat, Kent L. McDonald, J. Michael McCaffery, Marko Kaksonen, Hadiya A. Watson, Aaron C. Groen
Publikováno v:
The Journal of cell biology, vol 162, iss 5
The Journal of Cell Biology
The Journal of Cell Biology
We used chemical genetics to control the activity of budding yeast Prk1p, which is a protein kinase that is related to mammalian GAK and AAK1, and which targets several actin regulatory proteins implicated in endocytosis. In vivo Prk1p inhibition blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3ff4aebbf92270094084a06928bb936
https://escholarship.org/uc/item/1zc120nm
https://escholarship.org/uc/item/1zc120nm
Autor:
Thomas E. Renau, Georges Natsoulis, Jerry M. Buysse, Thomas Lila, Lori Wilson, Jay Philips, M. Jamie T.V. Cope, William J. Watkins
Compounds that selectively disrupt fungal mitosis have proven to be effective in controlling agricultural pests, but no specific mitotic inhibitor is available for the treatment of systemic mycoses in mammalian hosts. In an effort to identify novel m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77c6fbc215c2b0199c8e7442573c01e
https://europepmc.org/articles/PMC161869/
https://europepmc.org/articles/PMC161869/