Zobrazeno 1 - 10
of 61
pro vyhledávání: '"M. Jake Pushie"'
Autor:
David Hartnell, Wendy Andrews, Nicole Smith, Haibo Jiang, Erin McAllum, Ramesh Rajan, Frederick Colbourne, Melinda Fitzgerald, Virginie Lam, Ryusuke Takechi, M. Jake Pushie, Michael E. Kelly, Mark J. Hackett
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2020)
Diffusible ions (Na+, K+, Mg2+, Ca2+, Cl–) are vital for healthy function of all cells, especially brain cells. Unfortunately, the diffusible nature of these ions renders them difficult to study with traditional microscopy in situ within ex vivo br
Externí odkaz:
https://doaj.org/article/c828a0067b5d490abeb74231f968feee
Autor:
Thomas P. Warelow, M. Jake Pushie, Julien J. H. Cotelesage, Joanne M. Santini, Graham N. George
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Arsenite oxidase is thought to be an ancient enzyme, originating before the divergence of the Archaea and the Bacteria. We have investigated the nature of the molybdenum active site of the arsenite oxidase from the Alphaproteobacterium Rhizo
Externí odkaz:
https://doaj.org/article/55118be17e5a408eac6c4e27b9f5fa69
Autor:
Natalie B. Schulte, M. Jake Pushie, Ana Martinez, Madison Sendzik, Maria Escobedo, Kristin Kuter, Kathryn L. Haas
Publikováno v:
Inorganic Chemistry. 62:4021-4034
Autor:
Cellas A. Hayes, Nyah I. Morgan, Kamryn C. Thomas, M. Jake. Pushie, Akshaya Vijayasankar, Brandon G. Ashmore, Kendall Wontor, Miguel A. De Leon, Nicole M. Ashpole
Publikováno v:
bioRxiv
Ischemic stroke is a leading cause of death and disability, as therapeutic options for mitigating the long-term deficits precipitated by the event remain limited. Acute administration of the neuroendocrine modulator insulin-like growth factor-1 (IGF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65083d7d967b10efa1a12020c6efc687
https://doi.org/10.1101/2023.04.02.535245
https://doi.org/10.1101/2023.04.02.535245
Publikováno v:
Dalton Transactions. 51:10361-10376
Copper(II) coordination by bis(cyclohexanone)oxalyldihydrazone (also known as cuprizone), resulting in the formation of an intensely coloured blue complex, was first reported over 70 years ago. The cuprizone reaction has been employed in colourimetri
Autor:
Kelly L. Summers, Graham Roseman, Kevin M. Schilling, Natalia V. Dolgova, M. Jake Pushie, Dimosthenis Sokaras, Thomas Kroll, Hugh H. Harris, Glenn L. Millhauser, Ingrid J. Pickering, Graham N. George
Publikováno v:
Inorg Chem
Although Alzheimer’s disease (AD) was first described over a century ago, it remains the leading cause of age-related dementia. Innumerable changes have been linked to the pathology of AD; however, there remains much discord regarding which might b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055469210add149db9276610ef37d92c
https://europepmc.org/articles/PMC9957665/
https://europepmc.org/articles/PMC9957665/
Autor:
Graham George, M. Jake Pushie
Publikováno v:
Dalton transactions (Cambridge, England : 2003). 51(27)
The reaction of copper with bis(cyclohexanone)oxaldihydrazone (cuprizone) is a challenging coordination chemistry problem that has confounded attempts at elucidation for the past 70 years. The product of the reaction, a blue copper complex, wherein t
Autor:
Huishu Hou, Massimiliano Massi, Thomas Becker, David Hartnell, Elizabeth Watkin, Nicole J. Sylvain, Anna Maria Ranieri, Jitraporn Vongsvivut, Michael Kelly, Keith R. Bambery, Mark J. Tobin, Hum Bahadur Lamichhane, M. Jake Pushie, Ashley Hollings, Mark J. Hackett
Publikováno v:
The Analyst. 146:3516-3525
Visualising direct biochemical markers of cell physiology and disease pathology at the sub-cellular level is an ongoing challenge in the biological sciences. A suite of microscopies exists to either visualise sub-cellular architecture or to indirectl
Autor:
Christopher A. Robinson, Claudia F. Lucchinetti, Yong Guo, Reginald C. Adiele, Samuel M. Webb, Wolfgang Brück, Kendra L Furber, M. Jake Pushie, Hans Lassmann, Joseph E. Parisi, Stephen D. Weigand, Josa M. Frischer, Mylyne Tham, Patrick D. Fitz-Gibbon, Bogdan F. Gh. Popescu
Publikováno v:
Annals of Neurology
OBJECTIVE Multiple sclerosis (MS) is a heterogeneous inflammatory demyelinating disease. Iron distribution is altered in MS patients' brains, suggesting iron liberation within active lesions amplifies demyelination and neurodegeneration. Whether the
Publikováno v:
Metallomics
Synchrotron-based X-ray fluorescence microscopy is a flexible tool for identifying the distribution of trace elements in biological specimens across a broad range of sample sizes. The technique is not particularly limited by sample type and can be pe