Zobrazeno 1 - 10
of 12
pro vyhledávání: '"M. J. Wasicko"'
Dopamine D2 receptor modulation of carotid body type 1 cell intracellular calcium in developing rats
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 288:L910-L916
Carotid chemoreceptor type 1 cells release dopamine, which inhibits carotid chemoreceptor activity via dopamine D2 autoreceptors on type 1 cells. Postnatal changes in dopaminergic modulation may be involved in postnatal chemoreceptor development. The
Publikováno v:
Europe PubMed Central
The O2sensitivity of carotid chemoreceptor type I cells is low just after birth and increases with postnatal age. Chronic hypoxia during postnatal maturation blunts ventilatory and carotid chemoreceptor neural responses to hypoxia, but the mechanism
Publikováno v:
Europe PubMed Central
The site of postnatal maturation of carotid body chemoreception is unclear. To test the hypothesis that maturation occurs synchronously in type I cells and the whole carotid body, the development of changes in the intracellular Ca2+concentration resp
Publikováno v:
Journal of Applied Physiology. 74:2694-2703
We sought to determine if the upper airway response to an added inspiratory resistive load (IRL) during wakefulness could be used to predict the site of upper airway collapse in patients with obstructive sleep apnea (OSA). In 10 awake patients with O
Publikováno v:
Journal of Applied Physiology. 74:73-81
Increased blood pressure (BP) leads to inhibition of respiratory activity of hypoglossal nerve in anesthetized cats, implying that arterial baroreceptor activity may inhibit upper airway motor outputs. We examined the effect of passive tilt on upper
Publikováno v:
Journal of Applied Physiology. 70:1265-1270
Our purpose was to compare further eupneic ventilatory activity with that of gasping. Decerebrate, paralyzed, and ventilated cats were used; the vagi were sectioned within the thorax caudal to the laryngeal branches. Activities of the phrenic nerve a
Publikováno v:
Journal of Applied Physiology. 68:53-58
To determine if depression of central respiratory output during progressive brain hypoxia (PBH) can be generalized to other brain stem outputs, we examined the effect of PBH on the tonic (tSCS) and inspiratory-synchronous (iSCS) components of pregang
Publikováno v:
The Journal of physiology. 514
Regulation of arterial oxygen levels is critically important in mammals, particularly during early life. Peri- and postnatal hypoxia may lead to impaired cognitive development, abnormalities in cardiovascular function, breathing control maturation an
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 75(3)
We examined the relationship between hypoglossal and phrenic nerve activities and carotid sinus pressure. In 12 adult cats that were decerebrate, vagotomized, paralyzed, and mechanically ventilated, we isolated the left carotid sinus for perfusion an
Publikováno v:
The American review of respiratory disease. 144(5)
Phenylephrine, an alpha-adrenergic agonist, increases pharyngeal cross-sectional area when applied topically to the nasal and pharyngeal mucosa, as determined by magnetic resonance imaging. In this study, we examined the possibility that the increase