Zobrazeno 1 - 10
of 10
pro vyhledávání: '"M. J. Waddell"'
Autor:
M. J. Waddell, E. Gabriela Chiorean, Bryan P. Schneider, Srikar R. Malireddy, Christopher Sweeney, Stephen D. Hall, David R. Jones, Melissa I. Sloop, Anne Younger, Menggang Yu
Publikováno v:
Cancer Chemotherapy and Pharmacology. 66:441-448
To define the maximum-tolerated dose (MTD) for weekly paclitaxel administered in combination with daily vatalanib (PTK787/ZK 222584, PTK/ZK) and assess for a drug-drug interaction.Patients were treated with escalating doses of weekly paclitaxel (75-8
Autor:
M. J. Waddell, Cynthia S. Johnson, Robin Zon, David M. Waterhouse, Sreenivasa Nattam, Joel Picus, Christopher Sweeney, Noah M. Hahn, Walter M. Stadler, Susan M. Perkins
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 29(12)
Purpose Novel approaches are needed for patients with metastatic urothelial cancer (UC). This trial assessed the efficacy and toxicity of bevacizumab in combination with cisplatin and gemcitabine (CGB) as first-line treatment for patients with metast
Autor:
Katherine A. Carr, David Magjuka, Rivienne Shedd-Steele, Yousef Mohammadi, M. J. Waddell, Noah M. Hahn, Angela D. Reed, Marietta L. Moore, Edward F. Dropcho, Yash Patel, Christopher Sweeney
Publikováno v:
Cancer. 118(4)
BACKGROUND: Study of genomic data obtained from patient biospecimens is frequent in research of subjects with prostate and other epithelial malignancies. Understanding of the characteristics of healthy men who participate in genomic research is limit
Autor:
Yousef Mohammadi, Edward F. Dropcho, M. Bolden, J. Jung, N. M. Hahn, K. A. Carr, J. A. Knight, Yash Patel, C. Camp, Lang Li, Todd C. Skaar, Marietta L. Moore, Christopher Sweeney, M. J. Waddell, D. Magjuka, Jessica Dantzer, James E. Klaunig, Santosh Philips, Angela D. Reed
Publikováno v:
Journal of Clinical Oncology. 29:4645-4645
4645 Background: PCa risk is multi-factorial with both genetic and environmental influences. Candidate SNPs identifying risk of lethal PCa have been poorly characterized. This case control study wa...
Autor:
M. J. Waddell, George E. Sandusky, William A. Berry, M. R. Khawaja, Jennifer M. Funke, K. Pollok, Nagendra K. Prasad, E. G. Chiorean, David R. Jones, Anne Younger
Publikováno v:
Journal of Clinical Oncology. 29:TPS157-TPS157
TPS157 Background: The insulin growth factor (IGF) axis is overactive in many tumors and affects several downstream signaling pathways including PI3K/Akt/mTOR. Synergism between IGF and mTOR inhibi...
Autor:
Christopher Sweeney, M. J. Waddell, Susan M. Perkins, Joel Picus, Cynthia S. Johnson, Robin Zon, N. M. Hahn, David M. Waterhouse, Walter M. Stadler, Sreenivasa Nattam
Publikováno v:
Journal of Clinical Oncology. 28:4541-4541
4541 Background: Initial results of CGB therapy in metastatic UC patients demonstrated encouraging response and overall survival results with concerning rates of toxicity (Hahn et al ASCO 2008, abs...
Autor:
M. J. Waddell, Jennifer M. Funke, David R. Jones, K. Sandrasegaran, Christopher Sweeney, E. G. Chiorean, Susan M. Perkins, Daniela Matei, N. M. Hahn, Anne Younger
Publikováno v:
Journal of Clinical Oncology. 28:3043-3043
3043 Background: Prior data of dual VEGF-ligand/receptor blockade with B and S showed promising efficacy. P is active against many tumor types, and combined with B improves efficacy in breast and l...
Autor:
Susan M. Perkins, Robin Zon, M. J. Waddell, N. M. Hahn, Sreenivasa Nattam, Christopher Sweeney, David M. Waterhouse, Joel Picus, Cynthia S. Johnson, Walter M. Stadler
Publikováno v:
Journal of Clinical Oncology. 27:5018-5018
5018 Background: Despite CG therapy, most metastatic UC patients die from their disease. Novel approaches are needed. Combining anti-angiogenic therapy with chemotherapy has improved outcomes in other malignancies, offering hope for similar improveme
Autor:
LOUISE M. J. WADDELL
Publikováno v:
AJN, American Journal of Nursing. 5:274
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