Výsledky vyhledávání

Alveolar and peritoneal macrophages bear three distinct classes of Fc receptors for IgG

Autor: C L Anderson, R J Looney, D J Culp, D H Ryan, H B Fleit, M J Utell, M W Frampton, P D Manganiello, P M Guyre

Publikováno v: The Journal of Immunology. 145:196-201

The FcR for IgG on the plasma membrane of cells of the mononuclear phagocyte system mediate a number of different biologic responses such as phagocytosis, pinocytosis, superoxide generation, and antibody-dependent cytotoxicity. In the interest of und

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0af9c56e3ac07cc32c85c221e08d525b
https://doi.org/10.4049/jimmunol.145.1.196

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Human alveolar macrophage FcR-mediated cytotoxicity. Heteroantibody- versus conventional antibody-mediated target cell lysis

Autor: P C Levy, R J Looney, L Shen, R F Graziano, M W Fanger, N J Roberts, D H Ryan, M J Utell

Publikováno v: The Journal of Immunology. 144:3693-3700

Human alveolar macrophage have three distinct receptors for IgG: FcRI, FcRII, and FcRIII. In order to compare the ability of these receptors to mediate target cell lysis, three different assay systems were examined. First, we studied lysis of chicken

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e79a8de417af2824b1eeab508a555b7
https://doi.org/10.4049/jimmunol.144.10.3693

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Aldehydes (nonanal and hexanal) in rat and human bronchoalveolar lavage fluid after ozone exposure

Autor: M W, Frampton, W A, Pryor, R, Cueto, C, Cox, P E, Morrow, M J, Utell

Publikováno v: Research report (Health Effects Institute). (90)

We hypothesized that exposure of healthy humans to ozone at concentrations found in ambient air causes both ozonation and peroxidation of lipids in lung epithelial lining fluid. Smokers (12) and nonsmokers (15) were exposed once to air and twice to 0

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1c5d3309edbcd9b8e18228f668e325a0
https://pubmed.ncbi.nlm.nih.gov/10734666

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Metabolism of 1,1-dichloro-1-fluoroethane (HCFC-141b) in human volunteers

Autor: Z, Tong, M J, Utell, P E, Morrow, G M, Rusch, M W, Anders

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 26(7)

Human subjects were exposed by inhalation to 250, 500, and 1000 ppm 1,1-dichloro-1-fluoroethane (HCFC-141b) for 4 hr, and urine samples were collected from 0-4, 4-12, and 12-24 hr for metabolite analysis. 19F nuclear magnetic resonance spectroscopic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bb0631f9aba760f54bb9f62d889b95aa
https://pubmed.ncbi.nlm.nih.gov/9660855

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Mutational spectra of a 100-base pair mitochondrial DNA target sequence in bronchial epithelial cells: a comparison of smoking and nonsmoking twins

Autor: H A, Coller, K, Khrapko, A, Torres, M W, Frampton, M J, Utell, W G, Thilly

Publikováno v: Cancer research. 58(6)

Seventeen separate mitochondrial hot spot mutations in a 100-bp target sequence (mitochondrial bp 10,030-10,130) were detected and measured in bronchial epithelial cell samples isolated from smokers and nonsmokers. Among the individuals sampled were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a25b64db665127a0251124a976f1b7bb
https://pubmed.ncbi.nlm.nih.gov/9515815

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Effects of ozone on normal and potentially sensitive human subjects. Part III: Mediators of inflammation in bronchoalveolar lavage fluid from nonsmokers, smokers, and asthmatic subjects exposed to ozone: a collaborative study

Autor: M W, Frampton, J R, Balmes, C, Cox, P M, Krein, D M, Speers, Y, Tsai, M J, Utell

Publikováno v: Research report (Health Effects Institute). (78)

To provide bases of comparison between the studies described in Parts I and II of this Research Report, concentrations of interleukin 6 (IL-6)*, interleukin 8 (IL-8), and alpha 2-macroglobulin (a2M) were measured in airway lavage fluids obtained in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::de5bc0571258f36396ff7d3cb4c66a1c
https://pubmed.ncbi.nlm.nih.gov/9387197

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Effects of ozone on normal and potentially sensitive human subjects. Part II: Airway inflammation and responsiveness to ozone in nonsmokers and smokers

Autor: M W, Frampton, P E, Morrow, A, Torres, K Z, Voter, J C, Whitin, C, Cox, D M, Speers, Y, Tsai, M J, Utell

Publikováno v: Research report (Health Effects Institute). (78)

Exposure to ozone at levels near the National Ambient Air Quality Standard causes respiratory symptoms, changes in lung function, and airway inflammation. Although ozone-induced changes in lung function have been well characterized in healthy individ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4427ab9373c8c1b0e9c45b1540268d24
https://pubmed.ncbi.nlm.nih.gov/9387196

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