Zobrazeno 1 - 5
of 5
pro vyhledávání: '"M. J. Uprichard"'
Autor:
M. A. Barve, W. Fisher, Z. Yang, H. Patel, F. W. Nugent, E. C. Jurkowski, E. Meiri, Y. V. Oza, M. J. Uprichard, C. Cunningham
Publikováno v:
Journal of Clinical Oncology. 25:4616-4616
4616 Background: Talabostat is an oral small molecule inhibitor of fibroblast activation protein (FAP), a stromal enzyme with collagenase and dipeptidyl peptidase activity. Talabostat also upregulates cytokine and chemokine production, resulting in i
Autor:
J. Stephenson, Steven J. O'Day, G. Frenette, Anna C. Pavlick, Z. Yang, C. Cunningham, K. Khan, M. J. Uprichard, Ricardo J. Gonzalez, V. Vrhovac
Publikováno v:
Journal of Clinical Oncology. 24:8040-8040
8040 Background: Talabostat (TAL) is an oral inhibitor of dipeptidyl peptidases such as fibroblast activation protein found on the stroma of tumors, draining lymph nodes, and in melanomas. TAL up-regulates cytokines and chemokines, leading to specifi
Autor:
K. D. Khan, Camille N. Abboud, Kanti R. Rai, E. J. Haltom, P. Conkling, David D. Hurd, M. J. Uprichard, Jennifer R. Brown, Z. Yang, Susan O'Brien
Publikováno v:
Journal of Clinical Oncology. 24:6598-6598
6598 Background: Talabostat (TAL) is an orally administered small molecule inhibitor of dipeptidyl peptidases such as CD26 and fibroblast activation protein (FAP) in bone marrow, lymph nodes, and stroma of solid tumors, and TAL induces cytokine and c
Autor:
Robert N. Raju, R. Leonard, Casey Cunningham, S. Packer, Ravi Salgia, Donald A. Richards, J. Arseneau, L. Gregoire, M. J. Uprichard, E. Haltom
Publikováno v:
Journal of Clinical Oncology. 23:7120-7120
7120 Background: Talabostat (T) is an oral inhibitor of dipeptidyl peptidases such as fibroblast activation protein found on the stroma of tumors. Administration of T stimulates cytokine and chemok...
Autor:
V. Vrhovac, Donald A. Richards, Stephen P. Anthony, J. Stephenson, M. J. Uprichard, C. Cunningham, Anna C. Pavlick, Steven J. O'Day, G. Frenette, P. A. Pacciucci
Publikováno v:
Journal of Clinical Oncology. 23:7563-7563
7563 Background: Talabostat (T) is an oral inhibitor of dipeptidyl peptidases including fibroblast activation protein found on the stroma of tumors and in melanomas. T stimulates cytokine and chemo...