Zobrazeno 1 - 7
of 7
pro vyhledávání: '"M. J. Trumble"'
Publikováno v:
Journal of Biological Chemistry. 259:9395-9403
GH3 rat anterior pituitary cells possess a Na+/Ca2+ exchange transport mechanism which is present in purified plasma membrane vesicles prepared from these cells. Imposition of an outwardly directed Na+ gradient in vesicles results in a marked concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fa5f0afc80d79f9990dbac14f954c02
https://doi.org/10.1016/s0021-9258(17)42714-1
https://doi.org/10.1016/s0021-9258(17)42714-1
Publikováno v:
Journal of Biological Chemistry. 259:15013-15016
Specific, saturable, and reversible binding of verapamil has been demonstrated in crude cardiac sarcolemmal membranes. These receptors possess a Kd of approximately 50 nM for verapamil as determined by either equilibrium binding studies, competition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9b7508b28cecb7e86c799bcf3f9d9eb
https://doi.org/10.1016/s0021-9258(17)42505-1
https://doi.org/10.1016/s0021-9258(17)42505-1
Autor:
R. J. Winquist, Patricia K. Lumma, David E. McClure, David A. Claremon, S. A. Rosenthal, Gregory J. Kaczorowski, E. P. Faison, John J. Baldwin, Graham M. Smith, M. J. Trumble
Publikováno v:
ChemInform. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3468bdbeac6034577f60fe408ddaa3c3
https://doi.org/10.1002/chin.198737259
https://doi.org/10.1002/chin.198737259
Na+/Ca2+ exchange is inhibited in both guinea pig cardiac membrane vesicles and papillary muscles in a concentration-dependent fashion by several analogs of the pyrazine diuretic amiloride. Structure/activity studies based on transport measurements i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0fce1f938c619719fca1a6fadb66b92
https://europepmc.org/articles/PMC345257/
https://europepmc.org/articles/PMC345257/
Publikováno v:
The Journal of biological chemistry. 259(24)
Specific, saturable, and reversible binding of verapamil has been demonstrated in crude cardiac sarcolemmal membranes. These receptors possess a Kd of approximately 50 nM for verapamil as determined by either equilibrium binding studies, competition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9315f2eabe1a4ee4e9bdcb63454a8dbf
https://pubmed.ncbi.nlm.nih.gov/6096353
https://pubmed.ncbi.nlm.nih.gov/6096353
Publikováno v:
Biochemistry. 24(6)
Amiloride is a weak inhibitor of Na+/Ca2+ exchange in isolated plasma membrane vesicles prepared from GH3 rat anterior pituitary cells. However, substitution on either a terminal guanidino nitrogen atom or the 5-amino nitrogen atom can increase inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b81f7b9b6f19955037bcc8f6e8b52b02
https://pubmed.ncbi.nlm.nih.gov/2580553
https://pubmed.ncbi.nlm.nih.gov/2580553
Publikováno v:
The Journal of biological chemistry. 259(15)
GH3 rat anterior pituitary cells possess a Na+/Ca2+ exchange transport mechanism which is present in purified plasma membrane vesicles prepared from these cells. Imposition of an outwardly directed Na+ gradient in vesicles results in a marked concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c57458504cbed8d393fdba7f75b260c8
https://pubmed.ncbi.nlm.nih.gov/6430901
https://pubmed.ncbi.nlm.nih.gov/6430901