Zobrazeno 1 - 10
of 454
pro vyhledávání: '"M. J. Steffen"'
Publikováno v:
Journal of Periodontal Research. 49:642-651
Background and Objective Smoking has been reported to increase the risk of periodontal disease by disrupting the balance of immune responses and tissue repair processes; however, this risk varies among smokers. Cotinine levels in saliva are routinely
Autor:
Lianrui Chu, Lakshmyya Kesavalu, J. L. Ebersole, M. J. Steffen, David P. Cappelli, S. C. Holt
Publikováno v:
Clinical and Experimental Immunology. 162:550-559
Summary This study tested the hypothesis that pregnant female baboons exhibit increased levels of various inflammatory mediators in serum resulting from ligature-induced periodontitis, and that these profiles would relate to periodontal disease sever
Publikováno v:
Journal of Periodontal Research. 45:1-7
Endotoxin classically describes the biologic activity of the lipopolysac-charide structure comprising the outer membrane of gram-negative bacteria (1). Lipopolysaccharide, through engagement of lipopolysaccharide-binding protein (2,3) in serum and CD
Publikováno v:
Journal of Periodontology. 80:1154-1165
Chronic oral infections that elicit host responses leading to periodontal disease are linked with various sequelae of systemic diseases. This report provides seminal information on the clinical and adaptive immunologic characteristics of a baboon mod
Autor:
Karen F. Novak, Dolphus R. Dawson, J. L. Ebersole, G. L. Branch-Mays, J. C. Gunsolley, M. J. Steffen, Julie A. Mattison, Donald K. Ingram, Mark A. Reynolds, M. J. Novak
Publikováno v:
Journal of Periodontal Research. 43:500-507
Background and Objective: Dietary manipulation, including caloric restriction, has been shown to impact host response capabilities significantly, particularly in association with aging. This investigation compared systemic inflammatory and immune-res
Publikováno v:
Oral Diseases. 1:129-138
OBJECTS: This report describes one of the first prospective studies delineating the relationship between infection, host antibody responses and disease exacerbations and remissions in a distinct subset of periodontitis patients infected with A. actin
Autor:
Dolph Dawson, Lakshmyya Kesavalu, M. J. Steffen, Sabapathi Sathishkumar, Jeffrey L. Ebersole, Chad Matthews, Vasudevan Bakthavatchalu
Publikováno v:
Infection and Immunity. 75:1704-1712
One of the predominant polymicrobial infections of humans is expressed clinically as periodontal disease. Porphyromonas gingivalis , Treponema denticola , and Tannerella forsythia have been strongly implicated as members of a pathogenic consortium in
Autor:
Dolph Dawson, M. J. Steffen, B. Raghu, J. L. Ebersole, B. Vasudevan, Arunabh Bhattacharya, Gabriel Fernandes, J. M. Novak, M. C. Correll, L. Kesavalu, E. Browning
Publikováno v:
Journal of Dental Research. 85:648-652
Gingival inflammation and alveolar bone resorption are hallmarks of adult periodontitis, elicited in response to oral micro-organisms such as Porphyromonas gingivalis. We hypothesized that omega (ω)-3 fatty acids (FA) dietary supplementation would m
Autor:
Michael Montgomery, M. J. Steffen, M. John Novak, Erik C. Mathys, Jeffrey L. Ebersole, Glen E. Mott, David P. Cappelli, Robert E. Singer
Publikováno v:
Annals of Periodontology. 7:102-111
The acute phase response (APR) represents a systemic counterpart to the localized inflammatory response. This report describes patient-oriented and non-human primate model studies to determine the effect of periodontal disease on systemic acute phase
Publikováno v:
Infection and Immunity. 68:5284-5292
Human gingival fibroblasts were challenged withTreponema pectinovorumandTreponema denticolato test three specific hypotheses: (i) these treponemes induce different cytokine profiles from the fibroblasts, (ii) differences in cytokine profiles are obse