Zobrazeno 1 - 10 of 27 pro vyhledávání: '"M. J. Robbins"'
1
Interactions of the C Terminus of Metabotropic Glutamate Receptor Type 1α with Rat Brain Proteins: Evidence for a Direct Interaction with Tubulin
Autor: A. C. Willis, R. A. J. McIlhinney, M. J. Robbins, F. Ciruela
Publikováno v: Journal of neurochemistry. 72(1)
Metabotropic glutamate receptors (mGluRs) are coupled to G protein second messenger pathways and modulate glutamate neurotransmission in the brain, where they are targeted to specific synaptic locations. As part of a strategy for defining the mechani
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e7692b499793a6c86fa405942762cf
https://pubmed.ncbi.nlm.nih.gov/29543338
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2
Characterization of the Dimerization of Metabotropic Glutamate Receptors Using an N-Terminal Truncation of mGluR1α
Autor: R. A. J. McIlhinney, Francisco Ciruela, M. J. Robbins, A. Rhodes
Publikováno v: Journal of Neurochemistry. 72:2539-2547
The metabotropic glutamate receptor mGluR1alpha in membranes isolated both from rat brain and from cell lines transfected with cDNA coding for the receptor migrates as a disulphide-bonded dimer on sodium dodecyl sulphate-polyacrylamide gels. Dimeriza
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec767a12ea93f227e5d518cdcaf3c1e9
https://doi.org/10.1046/j.1471-4159.1999.0722539.x
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3
Antimicrobial susceptibility of community-acquired lower respiratory tract bacterial pathogens isolated in the UK during the 1995-1996 cold season
Autor: David Felmingham, S. B. Shrimpton, Y Tesfaslasie, I. Harding, R. N. Grüneberg, M J Robbins
Publikováno v: Journal of Antimicrobial Chemotherapy. 41:411-415
The antimicrobial susceptibility of 1078 isolates of Haemophilus influenzae, 348 Streptococcus pneumoniae and 258 Moraxella catarrhalis was determined. Overall 15.1% of H. influenzae produced beta-lactamase; 98.8% were susceptible to co-amoxiclav, 85
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca0b4b97e167a4c6607c96e113119dcd
https://doi.org/10.1093/jac/41.3.411
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4
In-vitro activity of trovafloxacin, a new fluoroquinolone, against recent clinical isolates
Autor: G L Ridgway, H Bhogal, David Felmingham, K Ingley, M J Robbins, A Leakey, I Mathias, R. N. Grüneberg
Publikováno v: Journal of Antimicrobial Chemotherapy. 39:43-49
Trovafloxacin (CP-99,219) was very active against Gram-negative species examined including Haemophilus influenzae, Moraxella catarrhalis, Legionella spp., Neisseria spp. and Escherichia coli (MIC90s < or = 0.03 mg/L). In general trovafloxacin was twi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3b2da709aa98114fda78c2f15e1103
https://doi.org/10.1093/jac/39.suppl_2.43
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6
Evaluating Theories of Immunological Memory Using Large-Scale Simulations
Autor: M. J. Robbins, Simon M. Garrett
Publikováno v: Lecture Notes in Computer Science ISBN: 9783540281757
ICARIS
Immunological simulations offer the possibility of performing high-throughput experiments in silico that can predict, or at least suggest, in vivo phenomena. In this paper, we first validate an experimental immunological simulator, developed by the a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::184d8223298fb44b069e091e5146d4e2
https://doi.org/10.1007/11536444_15
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7
Interactions of the C terminus of metabotropic glutamate receptor type 1alpha with rat brain proteins: evidence for a direct interaction with tubulin
Autor: F, Ciruela, M J, Robbins, A C, Willis, R A, McIlhinney
Publikováno v: Journal of neurochemistry. 72(1)
Metabotropic glutamate receptors (mGluRs) are coupled to G protein second messenger pathways and modulate glutamate neurotransmission in the brain, where they are targeted to specific synaptic locations. As part of a strategy for defining the mechani
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::93f559b40d0ac1f9668a1197ae93c977
https://pubmed.ncbi.nlm.nih.gov/9886087
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8
The in-vitro activity of grepafloxacin against Chlamydia spp., Mycoplasma spp., Ureaplasma urealyticum and Legionella spp
Autor: G L Ridgway, M J Robbins, C. Dencer, H Salman, David Felmingham
Publikováno v: The Journal of antimicrobial chemotherapy. 40
The activity of grepafloxacin, a new orally active fluoroquinolone, was compared with the activities of ofloxacin, clarithromycin and doxycycline against Chlamydia pneumoniae, Chlamydia trachomatis, Mycoplasma pneumoniae, Mycoplasma hominis and Ureap
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c58f58d87d86fb5b97ce9d62a6053fc
https://pubmed.ncbi.nlm.nih.gov/9484871
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9
In-vitro modelling of the bactericidal activity of teicoplanin versus flucloxacillin as used in surgical prophylaxis, against Staphylococcus aureus
Autor: J. C. Newton, J. A. Steer, Gale B. Hill, M. J. Robbins, Apr Wilson
Publikováno v: The Journal of antimicrobial chemotherapy. 39(4)
The bactericidal activities of teicoplanin and flucloxacillin in a 50:50 mixture of human serum and Iso-sensitest broth were compared in an in-vitro pharmacokinetic model, at serum concentrations present during surgical prophylaxis. The bactericidal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63afe32d1c8b15e7f775d1535ec50fd
https://pubmed.ncbi.nlm.nih.gov/9145820
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