Zobrazeno 1 - 10
of 26
pro vyhledávání: '"M. J. Otto"'
Publikováno v:
Physical Review B. 92
Measurements of the electrical resistivity, from 1.5 to 300 K, and of the low temperature magnetoresistance of highly conductive carbon nanotube (CNT) fibers, obtained by wet-spinning from liquid crystalline phase (LCP), are reported. At high tempera
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 158
Eosinophilic otitis media (EOM) is a rare middle ear disease that may closely resemble therapy-resistant otitis media with effusion (OME). The diagnosis is made if eosinophil-rich fluid is present with two or more of the following minor criteria: (a)
Publikováno v:
Nederlands Tijdschrift voor Geneeskunde, 158:A8044. Bohn Stafleu van Loghum
BACKGROUND: Eosinophilic otitis media (EOM) is a rare middle ear disease that may closely resemble therapy-resistant otitis media with effusion (OME). The diagnosis is made if eosinophil-rich fluid is present with two or more of the following minor c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::eec30d9ade474af0cbe1aa3650a7e744
https://cris.maastrichtuniversity.nl/en/publications/ae505b51-8c67-4fc0-87e7-b69b59eec11f
https://cris.maastrichtuniversity.nl/en/publications/ae505b51-8c67-4fc0-87e7-b69b59eec11f
Autor:
Robert W. King, Helen Scarnati, Lee Bachelor, Sena Garber, Sylvia Stack, Dean L. Winslow, M. J. Otto
Publikováno v:
Antiviral Research. 28:13-24
The HIV-1 protease (PR) is essential for the production of mature virions. As such, it has become a target for the development of anti-HIV chemotherapeutics. Multiple passages of virus in cell culture in the presence of PR inhibitors have resulted in
Publikováno v:
AIDS Research and Human Retroviruses. 11:107-113
Proviral DNAs from 3 laboratory strains and 21 clinical isolates of HIV-1 were extracted from infected cells after proteinase K digestion and the protease gene was PCR amplified and sequenced directly by the Sanger method. In vitro susceptibilities o
Autor:
Hodge Carl Nicholas, Susan Erickson-Viitanen, Y. N. Wong, M. M. Rayner, M. J. Otto, Fernandez Ch, Aldrich Pe
Publikováno v:
Antiviral Chemistry and Chemotherapy. 5:257-262
Low-molecular-weight peptidyl aldehyde inhibitors of HIV protease that reach in vivo plasma concentrations after oral administration substantiailly in excess of the antiviral IC90 are described. We also report efforts to improve the potency and stabi
Autor:
Douglas L. Mayers, Helen Scarnati, James R. Lane, M. J. Otto, Dean L. Winslow, Arlene Bincsik
Publikováno v:
AIDS. 8:753-756
OBJECTIVE: To determine the in vitro susceptibility of primary clinical isolates and laboratory strains of HIV-1 to XM323. METHODS: The AIDS Clinical Trials Group/US Department of Defense p24 antigen-based consensus assay was used to determine in vit
Autor:
Prabhakar K. Jadhav, Lee Terry Bacheler, B. A. Stone, Jeffrey Allan Miller, M. J. Otto, M. Paul
Publikováno v:
Antiviral Chemistry and Chemotherapy. 5:111-121
A rapid, high-capacity assay for evaluating the potency of anti-HIV compounds was devised. This assay measures cell associated viral RNA levels 3 days after infection of susceptible T-cell lines grown in individual microtitre plate wells. Viral RNA w
Autor:
M J, Otto, R A, Whitaker
Publikováno v:
Methods in molecular medicine. 24
The duck hepatitis B virus (DHBV) genome contains a pol gene that codes for the viral polymerase protein. This enzyme, which is essential for the replication of the virus, has multiple activities including an RNA directed DNA polymerase or reverse tr
Autor:
Patrick Y.S. Lam, M. M. Rayner, C. D. Reid, S. Garber, L. T. Bacheler, Dean L. Winslow, Helen Scarnati, M. J. Otto
Publikováno v:
Antimicrobial Agents and Chemotherapy. 37:2606-2611
XM323 represents a novel class of potent inhibitors of human immunodeficiency virus (HIV) protease. In vitro studies have shown that inhibition of this enzyme translates into potent inhibition of replication of HIV type 1 (HIV-1) and HIV-2. The inhib