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pro vyhledávání: '"M. J. Gutbrod"'
Autor:
M. J. Gutbrod, B. Roche, J. I. Steinberg, A. A. Lakhani, K. Chang, A. J. Schorn, R. A. Martienssen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
While RNA interference is conserved across species, small RNA pathways are very diverse. In this study, Gutbrod et al. find that non-canonical roles of Dicer in genome stability are in fact deeply conserved from yeast to humans.
Externí odkaz:
https://doaj.org/article/f58af5f228e043a786ee2701bc67da9d
Autor:
M J, Gutbrod, B, Roche, J I, Steinberg, A A, Lakhani, K, Chang, A J, Schorn, R A, Martienssen
Publikováno v:
Nature communications. 13(1)
RNA interference is required for post-transcriptional silencing, but also has additional roles in transcriptional silencing of centromeres and genome stability. However, these roles have been controversial in mammals. Strikingly, we found that Dicer-