Výsledky vyhledávání - "M. J. Gunster"

The Polycomb group protein EZH2 is upregulated in proliferating, cultured human mantle cell lymphoma

Autor: Chris J.L.M. Meijer, Frank M. Raaphorst, Hanneke C. Kluin-Nelemans, M. J. Gunster, Arie P. Otte, Erik M. M. Manders, Hein P. J. Visser, Roel Willemze

Publikováno v: British Journal of Haematology. 112:950-958

Polycomb group (PcG) proteins are involved in the stable transmittance of the repressive state of their gene targets throughout the cell cycle. Mis-expression of PcG proteins can lead to proliferative defects and tumorigenesis. There are two separate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::203b931330ad2bc970aa5b8145aaa61d
https://doi.org/10.1046/j.1365-2141.2001.02641.x

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C-Terminal Binding Protein Is a Transcriptional Repressor That Interacts with a Specific Class of Vertebrate Polycomb Proteins

Autor: Richard George Antonius Bernardus Sewalt, Arie P. Otte, M. J. Gunster, David P. E. Satijn, J. van der Vlag

Publikováno v: Molecular and Cellular Biology. 19:777-787

In Drosophila the Polycomb (Pc) group (PcG) genes have been identified as being part of a cellular memory system that is responsible for the stable and heritable repression of gene expression (3, 16). The PcG genes are required for maintenance of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74dabb27ca21e1d3487946886ef4340
https://doi.org/10.1128/mcb.19.1.777

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Interference with the Expression of a Novel Human Polycomb Protein, hPc2, Results in Cellular Transformation and Apoptosis

Autor: Richard George Antonius Bernardus Sewalt, R. van Driel, Karien M. Hamer, C. Lambrechts, Arie P. Otte, David P. E. Satijn, J. van der Vlag, M. J. Gunster, D. J. Olson, H. Masselink

Publikováno v: Scopus-Elsevier
Molecular and Cellular Biology, 6076-6086. American Society for Microbiology
ISSUE=17;STARTPAGE=6076;ENDPAGE=6086;ISSN=0270-7306;TITLE=Molecular and Cellular Biology

Polycomb (Pc) is involved in the stable and heritable repression of homeotic gene activity during Drosophila development. Here, we report the identification of a novel human Pc homolog, hPc2. This gene is more closely related to a Xenopus Pc homolog,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53d2b8280d78122705feb3ad65760611
https://doi.org/10.1128/mcb.17.10.6076

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RING1 Is Associated with the Polycomb Group Protein Complex and Acts as a Transcriptional Repressor

Autor: Karien M. Hamer, Wouter Schul, Paul S. Freemont, J. van der Vlag, R. van Driel, Mark J. Alkema, Andrew J. Saurin, M. J. Gunster, David P. E. Satijn, Arie P. Otte

Publikováno v: Europe PubMed Central

The Polycomb (Pc) protein is a component of a multimeric, chromatin-associated Polycomb group (PcG) protein complex, which is involved in stable repression of gene activity. The identities of components of the PcG protein complex are largely unknown.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6ac53ef72fc9e97bda943f32fa416e
https://doi.org/10.1128/mcb.17.7.4105

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Differential expression of human Polycomb group proteins in various tissues and cell types

Autor: Elly Fieret, Frank M. Raaphorst, Karien M. Hamer, M. J. Gunster, Chris J.L.M. Meijer, Jan L. den Blaauwen, Arie P. Otte

Publikováno v: Journal of cellular biochemistry. Supplement.

Polycomb group proteins are involved in the maintenance of cellular identity. As multimeric complexes they repress cell type-specific sets of target genes. One model predicts that the composition of Polycomb group complexes determines the specificity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f04f85df11ff0f55f501c3cb8aa8c4
https://pubmed.ncbi.nlm.nih.gov/11455578

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The Polycomb group protein EZH2 is upregulated in proliferating, cultured human mantle cell lymphoma

Autor: H P, Visser, M J, Gunster, H C, Kluin-Nelemans, E M, Manders, F M, Raaphorst, C J, Meijer, R, Willemze, A P, Otte

Publikováno v: British journal of haematology. 112(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aa9e74afffe8813b932d4b437dc87dc0
https://pubmed.ncbi.nlm.nih.gov/11298590

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Characterization of interactions between the mammalian polycomb-group proteins Enx1/EZH2 and EED suggests the existence of different mammalian polycomb-group protein complexes

Autor: David P. E. Satijn, Thijs Hendrix, Richard George Antonius Bernardus Sewalt, Arie P. Otte, M. J. Gunster, Roel van Driel, Johan van der Vlag, Jan L. den Blaauwen, Karien M. Hamer

Publikováno v: Molecular and cellular biology. 18(6)

In Drosophila melanogaster, the Polycomb-group (PcG) and trithorax-group (trxG) genes have been identified as repressors and activators, respectively, of gene expression. Both groups of genes are required for the stable transmission of gene expressio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9ac93cc6fcdc884dab665465634a87
https://pubmed.ncbi.nlm.nih.gov/9584199

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Identification and characterization of interactions between the vertebrate polycomb-group protein BMI1 and human homologs of polyhomeotic

Autor: M van Lohuizen, M. J. Gunster, R. van Driel, Karien M. Hamer, David P. E. Satijn, Arie P. Otte, Mark J. Alkema, Diederik R.H. de Bruijn, J.L. den Blaauwen

Publikováno v: Molecular and Cellular Biology, 17, 2326-2335
Molecular and Cellular Biology, 17, 4, pp. 2326-2335

In Drosophila melanogaster, the Polycomb-group (PcG) genes have been identified as repressors of gene expression. They are part of a cellular memory system that is responsible for the stable transmission of gene activity to progeny cells. PcG protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3849a126838d3bbc13aa7e4adb409ced
https://europepmc.org/articles/PMC232081/