Výsledky vyhledávání - "M. J. Gallimore"

The antigenic binding site(s) of antibodies to factor XII associated with the antiphospholipid syndrome

Autor: Peter Nicholls, M. J. Gallimore, David Wynne Jones, Mark Winter, S.L. Harris

Publikováno v: Journal of Thrombosis and Haemostasis. 3:969-975

Phospholipid binding proteins, including factor XII (FXII), are known to be targeted by antiphospholipid antibodies (aPA). Factor XII antibodies (FXIIab) have been described in some patients with the antiphospholipid syndrome (APS) and have been show

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9382535eca950c8a1b1ae723fea612
https://doi.org/10.1111/j.1538-7836.2005.01334.x

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Plasma levels of factor XII, prekallikrein and high molecular weight kininogen in normal blood donors and patients having suffered venous thrombosis

Autor: Simon L Harris, David Wynne Jones, Mark Winter, M. J. Gallimore

Publikováno v: Thrombosis Research. 114:91-96

Introduction : The contact system proteins factor XII (FXII), prekallikrein (PK) and high molecular weight kininogen (HK) have roles in coagulation, fibrinolysis, thrombin-induced platelet activation, cell adhesion and angeogenisis. It has been sugge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d81e99f3100e7957c53e5021b912c8
https://doi.org/10.1016/j.thromres.2004.05.005

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Antibodies to factor XII: a possible predictive marker for recurrent foetal loss

Autor: David Wynne Jones, M. J. Gallimore, Mark Winter

Publikováno v: Immunobiology. 207:43-46

Antibodies to factor XII (FXIIabs) have been demonstrated in some patients with the anti-phospholipid syndrome (APS). The presence of these antibodies were shown to lead to statistically significantly reduced levels of FXII (p = 0.02). In an extensio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be2ec8f5309dedbf4bc3a2f87c67a7e
https://doi.org/10.1078/0171-2985-00207

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Antibodies to Factor XII Are Distinct from Antibodies to Prothrombin in Patients with the Anti-phospholipid Syndrome

Autor: Jone Dw, M. J. Gallimore, Donohoe S, Peter Nicholls, Mark Winter

Publikováno v: Thrombosis and Haemostasis. 87:426-430

SummaryPatients with the anti-phospholipid syndrome (APS) have antiphospholipid antibodies (aPA) which are often targeted towards phospholipid binding proteins such as β2-glycoprotein I and prothrombin. Antibodies to factor XII (FXIIabs) have also b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7785e596e29497b3d1596cff3af084fd
https://doi.org/10.1055/s-0037-1613021

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Reduced factor XII levels in patients with the antiphospholipid syndrome are associated with antibodies to factor XII

Autor: M. J. Gallimore, I. J. Mackie, Mark Winter, S.L. Harris, D. W. Jones

Publikováno v: British Journal of Haematology. 110:721-726

Antibodies to factor XII (FXII) have previously been identified in some patients who were lupus anti-coagulant-positive. The relationship between these antibodies and FXII levels appeared to be variable. The aim of the present study was to confirm th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3657b7b280287dfeb489fbcb4588c9f7
https://doi.org/10.1046/j.1365-2141.2000.02251.x

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A Chromogenic Substrate Assay Kit for Factor XII

Autor: Hans Peter Wendel, D. W. Jones, M. J. Gallimore

Publikováno v: Thrombosis Research. 94:103-109

Factor XII levels were determined in plasma samples from 75 patients before undergoing aortocoronary bypass grafting and from 40 healthy age-matched donors by using a microtitre plate adaptation of a new chromogenic peptide substrate assay kit for fa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::942f5ea8a66ee8efcd373bd5626b3dc0
https://doi.org/10.1016/s0049-3848(98)00202-3

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Plasma proteolytic activity in liver transplant rejection

Autor: Ansgar O. Aasen, M. J. Gallimore, T. Scholz, Goran B. Klintmalm, Ø. Mathisen, Lars Bäckman, A. Bergan

Publikováno v: Transplant International. 12:100-107

In this study, we evaluated the role of proteolytic enzymes belonging to the coagulation, fibrinolytic, and plasma contact systems in the early postoperative phase after orthotopic liver transplantation (OLT). Twenty-nine patients were studied at the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e159c7760194143f88400d9aec658cb3
https://doi.org/10.1111/j.1432-2277.1999.tb00588.x

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Antibodies to Factor XII Associated with Lupus Anticoagulant

Autor: David Wynne Jones, M. J. Gallimore, Mark Winter, S.L. Harris

Publikováno v: Thrombosis and Haemostasis. 81:387-390

SummaryFalsely low levels of factor XII (FXII) have been documented in patients who are lupus anticoagulant positive (LA+). In addition, we have previously noted a surprisingly high incidence (20.9%) of apparently true FXII deficiency in patients who

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0af1528db5774f907e369223e9b30fca
https://doi.org/10.1055/s-0037-1614483

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Factor XII Determinations in the Presence and Absence of Phospholipid Antibodies

Autor: M. J. Gallimore, Mark Winter, D. W. Jones

Publikováno v: Thrombosis and Haemostasis. 79:87-90

SummaryFactor XII (FXII) levels were determined in plasma samples from 29 normal donors, 10 patients with inherited FXII deficiency (all lupus anticoagulant [LA] negative) and 67 LA positive patients, using clotting (FXIIct), chromogenic substrate (F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bfe8c20efe9f81e4d2dfcae88b70cdb1
https://doi.org/10.1055/s-0037-1614225

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