Zobrazeno 1 - 10
of 22
pro vyhledávání: '"M. J. Edelman"'
Publikováno v:
Cancer. 92(1)
The objective of this Phase II study was to evaluate the concept of sequential chemotherapy in the treatment of patients with advanced nonsmall cell lung carcinoma (NSCLC) by the administration of carboplatin plus gemcitabine followed by of paclitaxe
Publikováno v:
Oncology (Williston Park, N.Y.). 15(3 Suppl 6)
Combinations of gemcitabine (Gemzar) with cisplatin (Platinol) are among the most active new chemotherapy regimens developed for advanced non-small-cell lung cancer. Carboplatin (Paraplatin) is a platinum analog devoid of many of the nonhematologic t
Autor:
M J, Edelman
Publikováno v:
Chest surgery clinics of North America. 10(3)
Several new agents developed in the past decade have demonstrated activity in esophageal cancer. No single agent or combination of agents has been compared in a randomized study with the current standard, albeit limited, treatment of cisplatin and 5-
Publikováno v:
Oncology (Williston Park, N.Y.). 14(7 Suppl 4)
Platinum compounds, either cisplatin (Platinol) or carboplatin (Paraplatin), in combination with a number of new chemotherapeutic agents, have demonstrated improved response or survival compared to cisplatin alone or older platinum-based regimens. Ge
Autor:
P C, Mack, D R, Gandara, C, Bowen, M J, Edelman, T, Paglieroni, J B, Schnier, E P, Gelmann, P H, Gumerlock
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(9)
7-Hydroxystaurosporine (UCN-01), a protein kinase inhibitor in clinical development, demonstrates potent antineoplastic activity. To determine whether specific genetic abnormalities would modulate the response to UCN-01, a model of human non-small ce
Autor:
M J, Edelman, D R, Gandara, F J, Meyers, R, Ishii, M, O'Mahony, M, Uhrich, I, Lauder, J, Houston, D W, Gietzen
Publikováno v:
Cancer. 86(4)
Imbalanced amino acid diets in animals rapidly produce anorexia and weight loss. Blockade of type 3 serotonergic receptors (5HT(3)) can ameliorate anorexia in this animal model. Imbalanced plasma amino acid levels also have been documented in both an
Publikováno v:
Seminars in oncology. 26(3 Suppl 10)
In the first-line treatment of advanced non-small cell lung cancer (NSCLC), phase II trials of single-agent docetaxel (Taxotere; Rhône-Poulenc Rorer, Antony, France) at a dose of 100 mg/m2 every 3 weeks have reported encouraging results, with an ove
Autor:
M J, Edelman
Publikováno v:
The oncologist. 4(3)
Publikováno v:
Seminars in oncology. 26(1 Suppl 4)
Gemcitabine has demonstrated single-agent activity in advanced, incurable non-small cell lung cancer, yielding response rates ofor =20%. In combination with cisplatin, response rates of 30% to 60% and encouraging survival have been observed. Carbopla
Publikováno v:
The Western journal of medicine. 168(6)