Zobrazeno 1 - 10
of 26
pro vyhledávání: '"M. J. Dauphinée"'
Publikováno v:
The Journal of Immunology. 144:1375-1381
Antibodies to the small nucleoprotein Sm occur spontaneously in human and murine systemic lupus erythematosus. Human and mouse monoclonal anti-Sm autoantibodies designated 4B4 and Y2 share an idiotype (Id) determinant located on the Ig H chain. To un
Autor:
H, Dang, M J, Dauphinée, N, Talal, R F, Garry, J R, Seibold, T A, Medsger, S, Alexander, C A, Feghali
Publikováno v:
Arthritis and rheumatism. 34(10)
Publikováno v:
The Journal of Immunology. 142:2647-2653
Females have better humoral immune responses and are more susceptible to autoimmune diseases than males. Normal female mice (C57BL/6J, C3H/HeJ, and NZW) have significantly increased spontaneous autoimmune plaque-forming cells (APFC) to mouse erythroc
Publikováno v:
The Journal of Immunology. 127:2483-2487
IL 2 production was studied in autoimmune mice to assess the role of this lymphokine in the pathogenesis of murine lupus. Spleen and lymph node cells from autoimmune-susceptible mice show an age-dependent loss in the ability to produce functional IL
Publikováno v:
The Journal of Immunology. 124:1263-1266
We studied antigen-specific suppression in NZB and B/W mice to investigate immunoregulatory circuits associated with autoimmune disease. Young NZB and B/W mice produced ample suppressor factor, and acceptor cells were present even in older mice. A lo
Autor:
M. J. Dauphinée, Norman Talal
Publikováno v:
Scandinavian Journal of Immunology. 19:323-328
The autosomal recessive lpr gene (lymphoproliferative) has been bred into several normal strains of mice. Although the time of disease onset may vary, all of these lpr mice develop hypergammaglobulinaemia, antibodies to nucleoproteins, and massive ly
Publikováno v:
Agents and actions. Supplements. 7
Autor:
M J, Dauphinée, N, Talal
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 122(3)
Mouse bone marrow contains theta-negative lymphocytes that can suppress an in vitro plaque response by spleen cells primed in vivo with burro red blood cells (BRBC). These bone marrow cells are radiosensitive and can be induced with thymosin fraction
Publikováno v:
Arthritis and rheumatism. 25(7)
Autor:
Norman Talal, M. J. Dauphinée
Publikováno v:
Scandinavian journal of immunology. 22(6)
Tumour-promoting phorbol diesters are mitogenic for lymphocytes und induce differentiation of B and T cell lines as well as promyelocytic leukaemia cells. This paper demonstrates that l2-O-tetradecanoyl-13-acetate (PMA), when cocultured with normal m