Zobrazeno 1 - 10
of 10
pro vyhledávání: '"M. J. B. Jean-Francois"'
Autor:
P. Vaughan, Robert M. I. Kapsa, Anita F. Quigley, M. J. B. Jean-Francois, T. F. Han, Edward Byrne
Publikováno v:
Nucleic Acids Research. 26:4365-4373
Progressive age-related oxidative phosphorylation (OxPhos) decline is well known in human tissues. Depletion of mitochondrial DNA (mtDNA) causes OxPhos defects in patients with myopathic syndromes and deficient mtDNA replication has been observed in
Autor:
M J B Jean-Francois, C. M. Presgrave, D. Crimmins, Edward Byrne, John G. Morris, Roger Pamphlett, Y S Soo, Carolyn M. Sue, N Kotsimbos
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 65:233-240
OBJECTIVE To determine the neuroradiological abnormalities associated with subjects carrying the mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes (MELAS) tRNA Leu(UUR) A3243G point mutation METHODS Mitochondrial geneti
Publikováno v:
International Archives of Allergy and Immunology. 95:122-127
Primary immune responses to tetanus toxoid (TT) and primary and secondary immune responses to a rabbit TT internal image bearing anti-idiotype antibody (Ab2β1) inoculated in Freund’s complete adjuvant (FCA), saline (SAL) or syntex adjuvant formula
Autor:
Dominic Thyagarajan, A. S. Noer, Patcharee Lertrit, Sangkot Marzuki, Robert M. I. Kapsa, Edward Byrne, M. J. B. Jean-Francois
Publikováno v:
Human molecular genetics. 3(11)
Intergenomic variation in the human mitochondrial genome was examined in 27 mtDNA sequences using a pairwise analysis technique. Analysis of 16 of these mtDNA sequences from patients with mitochondrial cytopathies indicated a wide range between diffe
Publikováno v:
Vaccine. 9(11)
Anti-idiotype antibodies that carry an internal image of an antigen epitope (Ab2β antibodies) can be used in vaccine preparations to favourably manipulate the immune network. These vaccines have been shown to induce protective immunity in animals th
Publikováno v:
Immunology and cell biology. 69
The nature of immunoglobulin idiotypes and idiotype-anti-idiotype interactions in immunological networks
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 868:178-182
Mutations in the structural gene for the H+-ATPase subunit 9 which prevent the assembly of this subunit to the enzyme complex also affect the synthesis of subunit 6. The synthesis of these two F0-sector proteins appears to be co-ordinated at a post-t
Autor:
Richard G. Hadikusumo, Anthony W. Linnane, M. J. B. Jean-Francois, Wan Mee Choo, Sybella Meltzer, S. Marzuki
Publikováno v:
Biochimica et biophysica acta. 933(1)
mit- mutants with genetically defined mutations in the mitochondrial structural genes of the H+-ATPase membrane subunits 6, 8 and 9 were analysed to determine the H+-ATPase assembly defects that resulted as a consequence of the mutations. These inclu
Publikováno v:
Biochimica et biophysica acta. 933(1)
Five stable lines of myeloma-spleen cell hybrids, producing antibodies against the proteolipid subunit 9 of the yeast mitochondrial H+-ATPase F0-sector, have been isolated by immunizing mice with a proteolipid preparation in the presence of sodium do
Autor:
D. Crimmins, M. J. B. Jean-Francois, Samuel F. Berkovic, Patcharee Lertrit, Edward Byrne, Sangkot Marzuki, John G. Morris
Publikováno v:
Scopus-Elsevier
Background: Point mutations in the mitochondrial (mt) genome underlie a number of neurological disorders. Some are well defined including the myoclonus epilepsy ragged red fibre syndrome (MERRF) and the mitochondrial encephalopathy lactic acidosis st
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