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Effect of antibiotics on non-growing planktonic cells and biofilms of Escherichia coli

Autor: J. E. Neale, M. J. Ashby, I. A. Critchley, S. J. Knott

Publikováno v: Journal of Antimicrobial Chemotherapy. 33:443-452

Several classes of antibiotics were assessed for activity against non-growing Escherichia coli and cells grown as a biofilm. Antibiotics which had activity against non-growing cells also showed some activity against biofilms. Cephamycins were more ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85664753ab2b1de3b52e77365ecbb233
https://doi.org/10.1093/jac/33.3.443

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Characterization of [125I]-PD164333, an ETA selective non-peptide radiolabelled antagonist, in normal and diseased human tissues

Autor: A P, Davenport, R E, Kuc, M J, Ashby, W C, Patt, A M, Doherty

Publikováno v: British journal of pharmacology. 123(2)

1 We have synthesized a new low molecular weight, non-peptide radioligand, [125I]-PD164333, an analogue of the orally active butenolide antagonists of the endothelin ETA receptor. 2 Analysis of saturation binding assays demonstrated that [125I]-PD164

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f6c0da58dfb446f226e7ff154523041a
https://pubmed.ncbi.nlm.nih.gov/9489609

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BROMOCRIPTINE SUPPRESSES ACTH SECRETION FROM HUMAN PITUITARY TUMOUR CELLS IN CULTURE BY A DOPAMINERGIC MECHANISM

Autor: Susan M. Brown, E. F. Adams, M. C. White, M. J. Ashby, Keith Mashiter

Publikováno v: Clinical Endocrinology. 15:479-484

Bromocriptine (0.13-13 microM) significantly inhibited ACTH secretion in a dose-dependent manner when added to cell cultures of a human corticotrophic adenoma for 24 h. Haloperidol (13 microM), but not serotonin (13 microM), blocked this inhibition b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8d6ccc5c7bd1a6a66c5421412da4ef
https://doi.org/10.1111/j.1365-2265.1981.tb00691.x

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Effect of ketoconazole on adrenocorticotrophic hormone secretion in vitro and in vivo

Autor: M. J. Ashby, T. H. Yeo, S. R. Bloom, Jacky M. Burrin

Publikováno v: The Journal of endocrinology. 108(1)

The direct effects of ketoconazole on ACTH secretion have been investigated using a rat pituitary cell culture system. Ketoconazole had no significant effects on basal ACTH secretion, corticotrophin-releasing factor- or arginine vasopressin-stimulate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a9ec3d16e58def35cb181cc24a8494
https://pubmed.ncbi.nlm.nih.gov/3003220

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Effect of nivazol on ACTH secretion by human pituitary corticotrophic tumours in cell culture

Autor: Keith Mashiter, R. Drucker, Jacky M. Burrin, M. J. Ashby, E. F. Adams, T. H. Yeo, K. Stringer

Publikováno v: Clinical endocrinology. 22(5)

SUMMARY The effects of nivazol, a novel steroid which lacks glucocorticoid activity, on ACTH secretion by cell cultures of human pituitary corticotrophic tumours has been investigated. Nivazol (0·002-20 μmol/1) inhibited ACTH secretion by 50–80%,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669295595390ae034e4ae1db7315a66c
https://pubmed.ncbi.nlm.nih.gov/2992847

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Phaeochromocytoma with associated somatostatin production

Autor: M. J. Ashby, J. S. Price, Morris J. Brown, Alyn H. Morice

Publikováno v: BMJ. 298:1358-1359

We report on a patient with a phaechromocytoma in whom biochemical confirmation of the diagnosis was delayed because resting concentrations of catecholamines were normal, possibly because of the associated production of somatostatin by the tumour

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fbf46c0d2204723d2a5e1f5d8278c18b
https://doi.org/10.1136/bmj.298.6684.1358

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