Výsledky vyhledávání - "M. J. A. Verdonk"

Persistent CD3‐Crosslinking Down‐Regulates Interleukin‐2 Responsiveness in Interleukin‐2‐Competent Cloned T Cells: the Possible Involvement of Protein Kinase C

Autor: M. J. A. Verdonk, Mohamed R. Daha, B. A. C. Dijkmans, André M. M. Miltenburg, R. B. M. Landewé, F. C. Breedveld

Publikováno v: Scandinavian journal of immunology, 44(1), 45-53. Wiley-Blackwell

To investigate the regulation of interleukin-2 (IL-2) responsiveness of T cells, a human CD4+ T-cell clone with constitutive expression of IL-2 receptors was stimulated with recombinant IL-2 (rIL-2) in the presence or absence of immobilized anti-CD3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d13a1505206795aa6334874846e9cb76
https://doi.org/10.1046/j.1365-3083.1996.d01-280.x

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Effects of Inoculation with Attenuated Autologous T Cells in Patients with Rheumatoid Arthritis

Autor: F.C. Breedveld, André M. M. Miltenburg, R. R. P. De Vries, B.G. Elferink, M.R. Daha, J. M. Van Laar, M. J. A. Verdonk, Irun R. Cohen, A. Leow

Publikováno v: Journal of Autoimmunity. 6:159-167

Injection of attenuated autoimmune T cells, T cell vaccination, has been used successfully in the prevention and treatment of experimental animal autoimmune disease. In order to determine whether such a procedure might be applied in rheumatoid arthri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8416626fa80f35e02075b63cce0f82
https://doi.org/10.1006/jaut.1993.1013

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Activated Synovial T Cell Clones from a Patient with Rheumatoid Arthritis Induce Proliferation of Autologous Peripheral Blood-Derived T Cells

Autor: R. R. P. De Vries, B. G. Elferink, A. Leow, J. M. Van Laar, M. R. Daha, André M. M. Miltenburg, F. C. Breedveld, M. J. A. Verdonk

Publikováno v: Cellular Immunology. 146:71-79

In order to investigate cellular interactions involved in the development of human autoimmune disease, a synovial fluid-derived T cell clone reactive with mycobacterial antigens, termed k38, was employed as a stimulus for autologous peripheral blood

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae1a199eb1d08b1d2cd6d8f5b86699fd
https://doi.org/10.1006/cimm.1993.1007

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T-Cell Receptor beta-Chain Gene Rearrangements of T-Cell Populations Expanded from Multiple Sites of Synovial Tissue obtained from a Patient with Rheumatoid Arthritis

Autor: J. M. Van Laar, F. C. Breedveld, M. J. A. Verdonk, P.J. van den Elsen, André M. M. Miltenburg, R. R. P. De Vries, M. R. Daha

Publikováno v: Scandinavian Journal of Immunology. 35:187-194

In this study T-cell receptor (TcR) beta-chain gene rearrangements of T-cell lines prepared from multiple sites (n = 92) of synovial tissue derived from both knees of a patient with rheumatoid arthritis were analysed. In the majority of T-cell lines,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f61a62d7d99181dc8044858bfae58e1
https://doi.org/10.1111/j.1365-3083.1992.tb02849.x

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Lack of T cell oligoclonality in enzyme-digested synovial tissue and in synovial fluid in most patients with rheumatoid arthritis

Autor: André M. M. Miltenburg, P.J. van den Elsen, M. R. Daha, M. J. A. Verdonk, J. M. Van Laar, F. C. Breedveld, R. R. P. De Vries

Publikováno v: Clinical and Experimental Immunology. 83:352-358

SUMMARY The dominant presence or specific T-cell populations in the rheumatoid joint as detected by Southern blot analysis of T cell receptor (TCR) gene rearrangements would indicate local antigen recognition and T cell proliferation. We therefore st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aafc896a7c06cba21b0c14c5e9a672f7
https://doi.org/10.1111/j.1365-2249.1991.tb05642.x

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Chloroquine inhibits T cell proliferation by interfering with IL-2 production and responsiveness

Autor: André M. M. Miltenburg, B. A. C. Dijkmans, M. R. Daha, R. B. M. Landewé, M. J. A. Verdonk, Cornelis L. Verweij, Ferdinand C. Breedveld

Publikováno v: Clinical and experimental immunology, 102(1), 144-151. Wiley-Blackwell

SUMMARY Chloroquine (Chi) is an anti-rheumatic drug that is widely used in the treatment of rheumatoid arthritis (RA). It seems that T ceils are important in the pathogenesis of RA, but it is not known whether Chl acts via inhibition of T cell functi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caebadeea814aba0c4b7c5700be6131b
https://pure.amc.nl/en/publications/chloroquine-inhibits-t-cell-proliferation-by-interfering-with-il2-production-and-responsiveness(fd941473-38de-47bd-b9ff-6b80a819ce72).html

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