Zobrazeno 1 - 10
of 18
pro vyhledávání: '"M. J. A. G. Hamers"'
Autor:
Hans Jørgen Nielsen, Anders N. Pedersen, M. J. A. G. Hamers, Keld Dano, Gunilla Høyer-Hansen, Ross W. Stephens, Nils Brünner
Publikováno v:
Journal of Immunological Methods. 235:91-99
A significant degree of nonspecificity was found in ELISA determinations of soluble urokinase receptor (suPAR) in human blood plasma when biotinylated monoclonal antibodies (Mabs) were used for the detection layer. Surface plasmon resonance studies u
Publikováno v:
Thrombosis and Haemostasis. 83:334-337
SummaryPlatelet adhesion to the injured vessel wall is essential in haemostasis and thrombosis. This process involves the interaction of the platelet glycoprotein Ib (GPIb) with surface bound von Willebrand factor (vWF). Since synthetic polycationic
Publikováno v:
British Journal of Cancer
The urokinase plasminogen activator receptor (uPAR) plays a critical role in urokinase-mediated plasminogen activation and thereby in the process leading to invasion and metastasis. Soluble urokinase receptor (suPAR) is released from tumours, and in
Publikováno v:
Acta Radiologica. 39:349-354
Publikováno v:
Thrombosis and Haemostasis. 79:302-305
SummaryHeparin-coating improves the biocompatibility of blood contacting artificial surfaces. This led us to investigate the impact of heparin-coating (Carmeda AB, Stockholm) of polymetylmetacrylate on the expression of monocyte tissue factor procoag
Autor:
Hans Jørgen Nielsen, Anders N. Pedersen, Ebbe Rønne, Gunilla Høyer-Hansen, M. J. A. G. Hamers, Nils Brünner, Keld Danø, Ross W. Stephens, E Dybkjaer
Publikováno v:
Clinical Chemistry. 43:1868-1876
Measurement of urokinase receptor (uPAR) in tumor extracts has prognostic value, but assay of the soluble uPAR (suPAR) in peripheral blood may offer wider applications in cancer patient management. A tumor extract uPAR ELISA was modified to eliminate
Autor:
Nils Olav Solum, Kjell S. Sakariassen, U. Ørvim, Frank Brosstad, R. M. Barstad, Pål Andre Holme, M. J. A. G. Hamers
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 17:646-653
Abstract In the present study, we investigated whether high arterial shear stresses at various exposure times or a sudden increase in shear stress introduced by a stenosis affect platelet activation and platelet microparticle formation in native huma
Autor:
Ross W. Stephens, Lizette B. Petersen, M. J. A. G. Hamers, Kjell S. Sakariassen, Lars Örning, Helge Stormorken
Publikováno v:
Thrombosis Research. 86:57-67
We have found that synthetic peptides derived from the two epidermal growth factor-like domains of factor VII are inhibitors of tissue factor dependent factor X activation. Inhibition was most pronounced for a constrained sequence of amino acids corr
Autor:
Helge Stormorken, Lizette B. Petersen, Lars Örning, Ross W. Stephens, Kjell S. Sakariassen, M. J. A. G. Hamers
Publikováno v:
Thrombosis Research. 84:453-461
A novel model is described for characterisation of cell-surface procoagulant activities and their inhibitors. Microcarrier beads were used to present living cells to recalcified blood plasma in the stirred measuring wells of an electromagnetic coagul
Autor:
F. P. Brosstad, Kjell S. Sakariassen, Geir E. Tjønnfjord, M. J. A. G. Hamers, Una Ørvim, R. M. Barstad
Publikováno v:
Thrombosis and Haemostasis. 75:827-832
SummaryAspirin is the most commonly used antithrombotic drug in primary and secondary prophylaxis against cardio- and cerebrovascular disease. In previous studies from our laboratory it was demonstrated that the effect of aspirin on collagen-induced