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Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 4(4-5)
BALB 3T3 cells transfected by v-Ha-ras (Bhas 42 clone) were found to be sensitive to contact inhibition, but were susceptible to drastic transformation by 12-O-tetradecanoylphorbol-13-acetate. These results indicate that Bhas 42 cells are the initiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a1c6db83cef3fd5e1ee0696f588bc8
https://pubmed.ncbi.nlm.nih.gov/20702251
https://pubmed.ncbi.nlm.nih.gov/20702251
Publikováno v:
Mutation Research/Environmental Mutagenesis and Related Subjects. 234:141-145
Micronucleus induction by quinacrine dihydrochloride (Q) was tested in CD-1 male mice by single, double, and triple oral treatment(s) with 50 or 250 mg/kg. The mice were killed 24 h after the last treatment. Femoral marrow cells were analyzed on slid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad7ad0be34356f01817fd8190f4e5e0f
https://doi.org/10.1016/0165-1161(90)90006-a
https://doi.org/10.1016/0165-1161(90)90006-a
Publikováno v:
Mutation Research/Genetic Toxicology. 240:217-225
There is limited evidence that beryllium is a lung carcinogen to man, and several compounds of beryllium are carcinogenic to the lungs of the rat, rabbit and monkey. One such compound is beryllium sulphate (BeSO 4 · 4H 2 O). This soluble salt has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8efcc30315c3ec2203167eee00df3e7
https://doi.org/10.1016/0165-1218(90)90061-6
https://doi.org/10.1016/0165-1218(90)90061-6
Publikováno v:
Teratogenesis, Carcinogenesis, and Mutagenesis. 10:333-340
Quercetin was examined for the effects on the two-stage chemical transformation of BALB/3T3 cells. Quercetin showed initiating action to induce transformation in the cells which were treated with quercetin and subsequently with 0.49 microM 12-O-tetra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e94d6a7781aee52bdeabdd6d12413db
https://doi.org/10.1002/tcm.1770100406
https://doi.org/10.1002/tcm.1770100406
Publikováno v:
Mutation research. 404(1-2)
The chromosome aberration test using cultured mammalian cells is one of the sensitive methods to predict environmental mutagens and/or carcinogens, and is a complementary test to the Salmonella/microsome assay (Ames test). From our recent survey of 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e114ae548332d5fa804a4393640d80a
https://pubmed.ncbi.nlm.nih.gov/9729363
https://pubmed.ncbi.nlm.nih.gov/9729363
Autor:
S M, Galloway, T, Sofuni, M D, Shelby, A, Thilagar, V, Kumaroo, P, Kaur, D, Gulati, D L, Putman, H, Murli, R, Marshall, N, Tanaka, B, Anderson, E, Zeiger, M, Ishidate
Publikováno v:
Environmental and molecular mutagenesis. 29(2)
Different test results have been reported for the same chemicals in two in vitro chromosome aberration test systems, CHL cells tested by a Japanese protocol and CHO cells tested by the US National Toxicology Program [Sofuni et al., Mutat Res 241:173-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c1bf66765f75a8d5693540c5e9a632c0
https://pubmed.ncbi.nlm.nih.gov/9118971
https://pubmed.ncbi.nlm.nih.gov/9118971
Publikováno v:
The Journal of toxicological sciences. 16
Two in vitro tests with different genetic end points, gene mutation and chromosomal damage, and an in vivo test, preferably the micronucleus test in mice, were recommended as a battery system for the primary assessment of genotoxic effects of chemica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::64512f3a863d8b6ebaec3703afcf000a
https://pubmed.ncbi.nlm.nih.gov/1920547
https://pubmed.ncbi.nlm.nih.gov/1920547
Autor:
M, Ishidate
Publikováno v:
Yakushigaku zasshi. 26(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::947f2aadcd342320fde76c42f4f205f1
https://pubmed.ncbi.nlm.nih.gov/11623305
https://pubmed.ncbi.nlm.nih.gov/11623305
Autor:
M. Ishidate
Publikováno v:
Chromosomal Aberrations ISBN: 9783642756849
The majority of chemical mutagens and/or carcinogens interact with cellular DNA and are extremely potent in inducing chromosome damage in mammalian cells. A recent review of chromosomal aberration tests in vitro, on 951 chemical substances, from over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7ef88ecb13abc942274d274b00926cf
https://doi.org/10.1007/978-3-642-75682-5_25
https://doi.org/10.1007/978-3-642-75682-5_25
