Zobrazeno 1 - 10
of 19
pro vyhledávání: '"M. Isabel Collado"'
Autor:
Jesús Sot, Alicia Alonso, Hasna Ahyayauch, Jose Requejo-Isidro, M. Isabel Collado, Félix M. Goñi, Nerea Huarte
Publikováno v:
Biophysical Journal. 108(7):1672-1682
Diacylglycerol (DAG)-induced activation of phosphatidylinositol-phospholipase C (PI-PLC) was studied with vesicles containing PI, either pure or in mixtures with dimyristoyl phosphatidylcholine, distearoyl phosphatidylcholine, sphingomyelin, or galac
Autor:
Jesús Sot, Juan C. Gómez-Fernández, Alejandro Torrecillas, Ana Rosa Viguera, Félix M. Goñi, M. Isabel Collado, Alicia Alonso, Noemi Jiménez-Rojo
Publikováno v:
Biophysical Journal. 106:2577-2584
Sphingosine [(2S, 3R, 4E)-2-amino-4-octadecen-1, 3-diol] is the most common sphingoid long chain base in sphingolipids. It is the precursor of important cell signaling molecules, such as ceramides. In the last decade it has been shown to act itself a
Publikováno v:
Biophysical Journal. 102(11):2510-2516
It has been repeatedly observed that lipid bilayers in the gel phase are solubilized by lower concentrations of Triton X-100, at least within certain temperature ranges, or other nonionic detergents than bilayers in the fluid phase. In a previous stu
Publikováno v:
FEBS Letters. 583:2859-2864
The distribution of phosphatidylcholine (PC) and sphingomyelin (SM) between the solubilized (micellar) and non-solubilized (lamellar) fractions arising from bilayers composed of PC and SM, with or without cholesterol (Chol) has been measured under co
Autor:
Félix M. Goñi, Hasna Ahyayauch, Alicia Alonso, M. Isabel Collado, Jesús Sot, Nerea Huarte, Jose Requejo-Isidro
Publikováno v:
Biophysical Journal. 108(2)
DAG-induced activation of PI-PLC has been studied using as substrates vesicles containing PI, either pure or in mixtures with DMPC, DSPC, sphingomyelin, or galactosylceramide. At 22°C DAG at 33 mol% increases PI-PLC activity in all the mixtures, but
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Copyright © by Biophysical Society. Final full-text version of the paper available at: http://www.biophysj.org/cgi/content/abstract/88/5/3368
The effects on dielaidoylphosphatidylethanolamine (DEPE) bilayers of ceramides containing different N-
The effects on dielaidoylphosphatidylethanolamine (DEPE) bilayers of ceramides containing different N-
Publikováno v:
Langmuir. 18:2828-2835
The molecular basis for the existence of the so-called “detergent-resistant membranes” has been explored. With that aim, vesicles composed of phosphatidylcholine, sphingolipid, and cholesterol were...
Autor:
Chad Constance, Félix M. Goñi, Ana Rosa Viguera, M. Isabel Collado, Noemi Jiménez-Rojo, Kasey L. Hill, Walt A. Shaw, Kacee Sims, Alicia Alonso
Publikováno v:
Biochimica et biophysica acta. 1838(8)
Lipid peroxidation plays a central role in the pathogenesis of many diseases like atherosclerosis and multiple sclerosis. We have analyzed the interaction of sphingosine with peroxidized bilayers in model membranes. Cu2 + induced peroxidation was che
Publikováno v:
Tetrahedron Letters. 37:6193-6196
Efficient methodologies based on the nucleophilic addition-N-acyliminium ion cyclization and the Parham-type cyclization sequences of N-phenethylimides 1 and 2 are reported for the synthesis of a variety of heterocyclic systems: benzo[a]quinolizidone
Publikováno v:
Journal of Heterocyclic Chemistry. 32:1751-1758
The ortho-lithiation-cyclization of iodinated N,N-diacylphenethylamines provides a convenient method for the preparation of 2-(2-acetoamidoethyl)acetophenones and 2-(2-benzamidoethyl)benzophenones, which could be easily transformed into dihydroisoqui