Zobrazeno 1 - 10
of 46
pro vyhledávání: '"M. Isabel Calaza"'
Publikováno v:
European Journal of Organic Chemistry. 2015:1633-1658
An overview of synthetic methods developed to build [c]-fused bicyclic proline analogues is presented. The focus is on the preparation of azabicycles that bear a carbocyclic ring fused to the [c] face of the pyrrolidine unit. Attention is paid both t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cff07cdf55cbdfe8fadd148e513e3a5
https://doi.org/10.1002/ejoc.201403121
https://doi.org/10.1002/ejoc.201403121
Publikováno v:
ChemInform. 47
This review describes available methods for the preparation of α-aminoboronic acids in their racemic or in their enantiopure form. Both, highly stereoselective syntheses and asymmetric procedures leading to the stereocontrolled generation of α-amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb7d08acf42f762a9ce40a17f5031261
https://doi.org/10.1002/chin.201624234
https://doi.org/10.1002/chin.201624234
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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This review describes available methods for the preparation of α-aminoboronic acids in their racemic or in their enantiopure form. Both, highly stereoselective syntheses and asymmetric procedures leading to the stereocontrolled generation of α-amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea3abf4abf179a9d221159c48f0d7af
http://hdl.handle.net/10261/155737
http://hdl.handle.net/10261/155737
Autor:
Juan Torras, Ruth Nussinov, Francisco Rodríguez-Ropero, David Curcó, Ana I. Jiménez, David Zanuy, Carlos Cativiela, M. Isabel Calaza, Carlos Alemán, Guillem Revilla-López
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 79:1841-1852
Recently, we reported a database (NCAD, Non-Coded Amino acids Database; http://recerca.upc.edu/imem/index.htm) that was built to compile information about the intrinsic conformational preferences of non-proteinogenic residues determined by quantum me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::919f8804f936d6c36c1754d784800e52
https://doi.org/10.1002/prot.23009
https://doi.org/10.1002/prot.23009
Autor:
Carlos Cativiela, M. Isabel Calaza
Publikováno v:
Amino Acids, Peptides and Proteins in Organic Chemistry: Building Blocks, Catalysis and Coupling Chemistry, Volume 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f72d50df694034f220428ea28d82208c
https://doi.org/10.1002/9783527631803.ch2
https://doi.org/10.1002/9783527631803.ch2
Autor:
Carlos Cativiela, Erkki Ruoslahti, Ruth Nussinov, David Zanuy, Alejandra Flores-Ortega, M. Isabel Calaza, Ana I. Jiménez, Carlos Alemán
Publikováno v:
The Journal of Physical Chemistry B. 113:7879-7889
A new amino acid has been designed as a replacement for arginine (Arg, R) to protect the tumor-homing pentapeptide CREKA (Cys-Arg-Glu-Lys-Ala) from proteases. This amino acid, denoted (Pro)hArg, is characterized by a proline skeleton bearing a specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ef87e6fcab46f94156b70aa11d5ce2
https://doi.org/10.1021/jp9006119
https://doi.org/10.1021/jp9006119
Towards the stereoselective synthesis of α-methylated (2S,3aS,7aS)-octahydroindole-2-carboxylic acid
Publikováno v:
Tetrahedron: Asymmetry. 19:2763-2766
The incorporation of conformationally constrained α-amino acids into bioactive peptides is an effective strategy to circumvent the toughest issues in the development of peptide drugs: proteolytic degradation and poor bioavailability.1 Quaternary α-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0280d6d473c062278568b005f7c0437f
https://doi.org/10.1016/j.tetasy.2008.11.030
https://doi.org/10.1016/j.tetasy.2008.11.030
Autor:
Carlos Cativiela, M. Isabel Calaza
Publikováno v:
European Journal of Organic Chemistry. 2008:3427-3448
This review describes available methods for the diastereoselective and asymmetric synthesis of quaternary prolines. The focus is on the preparation of alpha-functionalized prolines with the pyrrolidine moiety not embedded in a polycyclic frame. The d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2080af997fccf10c1eb0388d9fd59cac
https://doi.org/10.1002/ejoc.200800225
https://doi.org/10.1002/ejoc.200800225
Publikováno v:
Tetrahedron. 64:84-91
An improved strategy for the effective synthesis of enantiomerically pure (2R,3aS,7aS)-octahydroindole-2-carboxylic acid (Oic), based on the formation of a trichloromethyloxazolidinone derivative, has been developed. Additionally, the completely dias
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a18a1be0d00a18e0f8df868a4d3f8f34
https://doi.org/10.1016/j.tet.2007.10.095
https://doi.org/10.1016/j.tet.2007.10.095
Publikováno v:
ChemInform. 46
Review: [procedures that afford the desired compounds in racemic form and asymmetric strategies; 92 refs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e57369d1b4af9d5eade06b463ccc461e
https://doi.org/10.1002/chin.201519301
https://doi.org/10.1002/chin.201519301