Longitudinal analysis of a dietary mouse model of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH)

Autor: Marissa Saenz, Jillian C. McDonough, Elizabeth Bloom-Saldana, Jose M. Irimia, Emily L. Cauble, Ashly Castillo, Patrick T. Fueger, Lindsey S. Treviño

Publikováno v: bioRxiv

Non-alcoholic fatty liver disease (NAFLD), and resultant non-alcoholic steatohepatitis (NASH), incidence and prevalence are rising globally due to increasing rates of obesity and diabetes. Currently, there are no approved pharmacological treatments f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d9f5492f081ef633b40aa9ead31fea
https://europepmc.org/articles/PMC10245692/

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Dose-dependent progression of multiple low dose streptozotocin-induced diabetes in mice

Autor: Brandon M. Bauer, Supriyo Bhattacharya, Elizabeth Bloom-Saldana, Jose M. Irimia, Patrick T. Fueger

This study investigated the effects of different multiple low doses of streptozotocin (STZ), namely 35 and 55 mg/kg, on the onset and progression of diabetes in mice. Both doses are commonly used in research, and while both induced a loss of beta cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1d6f48b3c91cd390240b13af5a4221bf
https://doi.org/10.1101/2023.04.08.536122

217-LB: Hepatic Mig6 Ablation Restores Glucose Homeostasis during Diet-Induced Obesity and Aging

Autor: JOSE M. IRIMIA-DOMINGUEZ, ELIZABETH A. BLOOM-SALDANA, PATRICK T. FUEGER

Publikováno v: Diabetes. 71

Hepatic epidermal growth factor receptor (EGFR) expression and activation are decreased during steatosis in humans and animal models of obesity. Restoring EGFR activation in obesity-induced endoplasmic reticulum (ER) stress and diabetes is a potentia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf90befc7d51fa76868445c61d6ea632
https://doi.org/10.2337/db22-217-lb

COMPREHENSIVE STUDIES ABOUT TROPHYC, ENVIRONMENTAL AND MEDICINAL IMPORTANCE OF TWO ROMANIAN HORTICULTURAL SOURCES: SEA BUCKTHORN (HIPPOPHAE RHAMNOIDES) AND TAMARISK (TAMARIX RAMOSISSIMA).

Autor: Iuliana-Maria, ENACHE, Ioana, BUTȚERCHI CĂLIN, Liliana, CIURLĂ LUCESCU, Antoanela, PATRAȘ, L. M., IRIMIA

Publikováno v: Lucrari Stiintifice, Universitatea de Stiinte Agricole Si Medicina Veterinara Ion Ionescu de la Brad Iasi, Seria Horticultura; 2023, Vol. 66 Issue 2, p15-26, 12p