Výsledky vyhledávání - "M. Irene Givogri"

Akademický článek

The Pathogenic Sphingolipid Psychosine is Secreted in Extracellular Vesicles in the Brain of a Mouse Model of Krabbe Disease

Autor: Cory R. Reiter, Rima Rebiai, Angelika Kwak, Jeff Marshall, Dylan Wozniak, Giusepe Scesa, Duc Nguyen, Emily Rue, Koralege C. Pathmasiri, Robert Pijewski, Richard van Breemen, Stephanie Cologna, Stephen J. Crocker, M Irene Givogri, Ernesto R Bongarzone

Publikováno v: ASN Neuro, Vol 14 (2022)

Psychosine exerts most of its toxic effects by altering membrane dynamics with increased shedding of extracellular vesicles (EVs). In this study, we discovered that a fraction of psychosine produced in the brain of the Twitcher mouse, a model for Kra

Externí odkaz: https://doaj.org/article/4a45a69642534fae9ba02c13cb43e826

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Akademický článek

Targeted Overexpression of a Golli-Myelin Basic Protein Isoform to Oligodendrocytes Results in Aberrant Oligodendrocyte Maturation and Myelination

Autor: Erin C Jacobs, Samuel D Reyes, Celia W Campagnoni, M Irene Givogri, Kathy Kampf, Vance Handley, Vilma Spreuer, Robin Fisher, Wendy Macklin, Anthony T Campagnoni

Publikováno v: ASN Neuro, Vol 1 (2009)

Recently, several in vitro studies have shown that the golli-myelin basic proteins regulate Ca 2+ homoeostasis in OPCs (oligodendrocyte precursor cells) and immature OLs (oligodendrocytes), and that a number of the functions of these cells are affect

Externí odkaz: https://doaj.org/article/6efd1e870c4846948c35393335f5fe77

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T2-weighted μMRI and Evoked Potential of the Visual System Measurements During the Development of Hypomyelinated Transgenic Mice

Autor: M. Irene Givogri, Scott E. Fraser, Anthony T. Campagnoni, Timothy D. Hiltner, Robin S. Fisher, Russell E. Jacobs, J. Michael Tyszka, Melanie Martin, Carol Readhead, Samuel D. Reyes

Publikováno v: Neurochemical Research. 32:159-165

Our objective was to follow the course of a dysmyelinating disease followed by partial recovery in transgenic mice using non-invasive high-resolution (117 x 117 x 70 microm) magnetic resonance (microMRI) and evoked potential of the visual system (VEP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9cfb4fbc21c7d06a05775e3192716f
https://doi.org/10.1007/s11064-006-9121-z

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Targeted Overexpression of a Golli-Myelin Basic Protein Isoform to Oligodendrocytes Results in Aberrant Oligodendrocyte Maturation and Myelination

Autor: M. Irene Givogri, Vilma Spreuer, Anthony T. Campagnoni, Erin C. Jacobs, Kathy Kampf, Wendy B. Macklin, Samuel D. Reyes, Robin S. Fisher, Celia W. Campagnoni, Vance Handley

Publikováno v: ASN Neuro, Vol 1 (2009)
ASN NEURO

Recently, several in vitro studies have shown that the golli-myelin basic proteins regulate Ca2+homoeostasis in OPCs (oligodendrocyte precursor cells) and immature OLs (oligodendrocytes), and that a number of the functions of these cells are affected

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5bb460b88c79360fc4605debe594820
https://doaj.org/article/6efd1e870c4846948c35393335f5fe77

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Identification of a novel silencer that regulates the myelin basic protein gene in neural cells

Autor: Kathy Kampf, Vilma Schonmann, M. Irene Givogri, Anthony T. Campagnoni

Publikováno v: Gene. 252(1-2)

The myelin basic protein gene produces two families of proteins, the golli proteins and the ‘classic’ myelin basic proteins from three transcription start sites (tsp). The golli proteins are expressed from the first tsp, and little is known about

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6430326a554b0972968af2f135b266e9
https://pubmed.ncbi.nlm.nih.gov/10903450

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Embryonic Expression of the Myelin Basic Protein Gene: Identification of a Promoter Region That Targets Transgene Expression to Pioneer Neurons

Autor: M. Irene Givogri, Charles F. Landry, T M Pribyl, Julie A. Ellison, Anthony T. Campagnoni, Kathy Kampf, Celia W. Campagnoni

The myelin basic protein (MBP) gene produces two families of structurally related proteins from three different promoters—the golli products, generated from the most upstream promoter, and the MBPs, produced from the two downstream promoters. In th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a76df3f3222b92053f0cd8684b4ed422
https://europepmc.org/articles/PMC6793259/

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Akademický článek

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Akademický článek

Targeted overexpression of a golli-myelin basic protein isoform to oligodendrocytes results in aberrant oligodendrocyte maturation and myelination.

Autor: Jacobs EC; Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA, Neuroscience Research Building, 635 Charles Young Drive, Los Angeles, CA 90095, USA., Reyes SD, Campagnoni CW, Irene Givogri M, Kampf K, Handley V, Spreuer V, Fisher R, Macklin W, Campagnoni AT

Publikováno v: ASN neuro [ASN Neuro] 2009 Sep 23; Vol. 1 (4). Date of Electronic Publication: 2009 Sep 23.

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