Výsledky vyhledávání - "M. I. Shigaeva"

Uridine treatment prevents myocardial injury in rat models of acute ischemia and ischemia/reperfusion by activating the mitochondrial ATP-dependent potassium channel

Autor: Valentina V. Bulion, Galina D. Mironova, Olga M. Rodionova, Irina B. Krylova, Natalia R. Evdokimova, M. I. Shigaeva, Elena N. Selina, Natalia V. Belosludtseva

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports

The effect of uridine on the myocardial ischemic and reperfusion injury was investigated. A possible mechanism of its cardioprotective action was established. Two rat models were used: (1) acute myocardial ischemia induced by occlusion of the left co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7859820855a2615679bec832db11cdb
https://doi.org/10.1038/s41598-021-96562-7

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A Comparison of Methods for Estimating the Activity of the ATP-Sensitive Potassium Channel in Mitochondria Based on the Effect of ATP

Autor: Natalya V. Khmil, M. I. Shigaeva, A. A. Mosencov, Galina D. Mironova

Publikováno v: Biophysics. 64:751-754

—Two methods for studying the functioning of the mitochondrial ATP-sensitive potassium channel, which plays an important role in cell physiology and especially in cardio- and neuroprotection, have been compared. It has been shown that the spectroph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c649a258d0e0e6069f584c930290544b
https://doi.org/10.1134/s0006350919050099

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Signaling Role of Mitochondrial Enzymes and Ultrastructure in the Formation of Molecular Mechanisms of Adaptation to Hypoxia

Autor: Natalya V. Khmil, Galina D. Mironova, L. D. Luk'yanova, E. L. Germanova, M. I. Shigaeva, Lybov Pavlik, I. B. Mikheeva

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 8636, p 8636 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 16

This study was the first comprehensive investigation of the dependence of mitochondrial enzyme response (catalytic subunits of mitochondrial complexes (MC) I-V, including NDUFV2, SDHA, Cyt b, COX1 and ATP5A) and mitochondrial ultrastructure in the ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d1ba27efd9092ce6a76b1ab45f8833
https://doi.org/10.3390/ijms22168636

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Detection of KIR6 family protein in rat heart and liver mitochondria by immunoelectron microscopy

Autor: E. Yu. Talanov, Galina D. Mironova, Natalia V. Belosludtseva, L. L. Pavlik, M. I. Shigaeva, D. A. Moshkov

Publikováno v: Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology. 8:121-124

The electron microscopic study of thin sections of rat liver and heart using commercial specific antibodies against KIR.6.2 and secondary antibodies conjugated with colloidal gold was performed. It was found that the gold-labeled protein is localized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2fce40fbe98cc92d7b68bfe4c0f26373
https://doi.org/10.1134/s1990747813050188

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Effect of several flavonoid-containing plant preparations on activity of mitochondrial ATP-dependent potassium channel

Autor: Galina D. Mironova, E. N. Gritsenko, Natalia V. Belosludtseva, E. L. Germanova, Konstantin N. Belosludtsev, L. D. Luk'yanova, M. I. Shigaeva

Publikováno v: Bulletin of Experimental Biology and Medicine. 146:229-233

Flavonoid-containing plant preparations (water soluble extracts of Pentaphylloides fruticosa [Extralife], Emblica officinalis Gaerth [Amla], and Bergenia crassifolia [Bergenia]) produced a dose-dependent and tissue-specific effect on activity of mito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1199eb624a77c75201f913e5ba128db
https://doi.org/10.1007/s10517-008-0255-7

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Oxidative phosphorylation and ion transport in the mitochondria of two strains of rats varying in their resistance to stress and hypoxia

Autor: E Lezhnev, Olga S. Gorbacheva, S. P. Belova, M. I. Shigaeva, L. D. Luk'yanova, Natalya I. Venediktova, Konstantin N. Belosludtsev, Galina D. Mironova, Natalia V. Belosludtseva

Publikováno v: Molecular and cellular biochemistry. 383(1-2)

The role of mitochondria in the inherited or ontogenetically acquired reactions of organism to stress is not studied enough. In the present work, we examined the functional state of the coupled respiratory chain, potassium and calcium transport and r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c435fcf0e16d7227ac8c79d6318fa7b
https://pubmed.ncbi.nlm.nih.gov/23943284

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Activity of mitochondrial ATP-dependent potassium channel in animals with different resistance to hypoxia before and after the course of hypoxic training

Autor: L. D. Luk'yanova, S. V. Murzaeva, M. I. Shigaeva, O. S. Gorbacheva, E. N. Gritsenko, Galina D. Mironova, E. L. Germanova

Publikováno v: Bulletin of experimental biology and medicine. 151(1)

Activity of mitochondrial ATP-dependent potassium channel in rats with high genetically determined resistance to hypoxia was higher than in sensitive animals. Adaptation of low resistant rats to hypoxia was accompanied by activation of the channel, f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5452963bf79aa066431363a2286bd9ce
https://pubmed.ncbi.nlm.nih.gov/22442795

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Functioning of the mitochondrial ATP-dependent potassium channel in rats varying in their resistance to hypoxia. Involvement of the channel in the process of animal's adaptation to hypoxia

Autor: E. N. Gritsenko, M. I. Shigaeva, Olga S. Gorbacheva, Galina D. Mironova, S. V. Murzaeva, L. D. Luk'yanova, Elena L. Germanova

Publikováno v: Journal of bioenergetics and biomembranes. 42(6)

The mechanism of tissue protection from ischemic damage by activation of the mitochondrial ATP-dependent K(+) channel (mitoK(ATP)) remains unexplored. In this work, we have measured, using various approaches, the ATP-dependent mitochondrial K(+) tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba232ef627202dc20bb00fb79d1721af
https://pubmed.ncbi.nlm.nih.gov/21082228

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Autor: E. Yu. Talanov, Galina D. Mironova, E. N. Gritsenko, S. V. Murzaeva, O. S. Gorbacheva, M. I. Shigaeva

Publikováno v: Scopus-Elsevier

Changes in the rate of respiration and functioning of the ATP-dependent potassium channel in liver and heart mitochondria of one-, three-, eight-, and 24-month-old Wistar male rats have been investigated. It was shown that the activity of the channel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1283cb994d3305e1a3ed7480d5866ba
http://www.scopus.com/inward/record.url?eid=2-s2.0-79952469606&partnerID=MN8TOARS

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[A role for calreticulin in functioning of mitochondrial ATP-dependent potassium channel]

Autor: M. I. Shigaeva, Eugeny Yu. Talanov, Galina D. Mironova, S. V. Murzaeva, Natalya I. Venediktova

Publikováno v: Scopus-Elsevier

Homology of the amino acid sequence of the mitochondrial potassium-transporting protein (MW 57 kDa), having the properties of a channel subunit of the mitochondrial ATP-dependent potassium channel, and calreticulin (MW 55 kDa) was detected by MALDI-T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eef5013fef5054e24d5bb3b48dee0e5
http://www.scopus.com/inward/record.url?eid=2-s2.0-84926120320&partnerID=MN8TOARS

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