Zobrazeno 1 - 10
of 21
pro vyhledávání: '"M. I. Mackness"'
Autor:
B. Mackness, A. E. Smith, M. I. Mackness, M. Dippnall, Nicola Cherry, Andrew C. Povey, P.N. Durrington
Publikováno v:
Occupational Medicine. 55:282-286
Serum paraoxonase (PON1) provides protection against organophosphate induced toxicity. Recently we reported that the frequency of paraoxonase polymorphisms in sheep dippers with self-reported chronic ill-health differed from that in dippers with a si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61391fd6506e7ddd4e04cc129ed7e18a
https://doi.org/10.1093/occmed/kqi128
https://doi.org/10.1093/occmed/kqi128
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 52(5)
Homocysteine (Hcy)-thiolactonase (HTase) activity of the paraoxonase-1 (PON1) protein detoxifies Hcythiolactone in human blood and could thus delay the development of atherosclerosis. We investigated a hypothesis that HTase activity is associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e06459324c050f47671d589d84a15ff5
https://pubmed.ncbi.nlm.nih.gov/17543199
https://pubmed.ncbi.nlm.nih.gov/17543199
Publikováno v:
European journal of clinical investigation. 32(4)
The oxidation of low-density lipoprotein (LDL) is central to current theories on the initiation and progression of atherosclerosis. Type 1 diabetes is associated with an increase in oxidative stress, which may be responsible for the increased suscept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d68190cd57d6536fdfaf1d74f64446d
https://pubmed.ncbi.nlm.nih.gov/11952805
https://pubmed.ncbi.nlm.nih.gov/11952805
Publikováno v:
The Biochemical journal. 354(Pt 1)
Human serum paraoxonase (human PON1) has been shown to be important in the metabolism of phospholipid and cholesteryl ester hydroperoxides, thereby preventing the oxidation of low-density lipoprotein (LDL) and retarding atherogenesis. However, the ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ca4d265193f502a60bb0553baf685d3
https://pubmed.ncbi.nlm.nih.gov/11171072
https://pubmed.ncbi.nlm.nih.gov/11171072
Autor:
P M, Sweetnam, C H, Bolton, L G, Downs, P N, Durrington, M I, MacKness, P C, Elwood, J W, Yarnell
Publikováno v:
European journal of clinical investigation. 30(11)
Apolipoproteins B, A-I and Lp(a) have been proposed as independent predictors of subsequent ischaemic heart disease (IHD) improving on the prediction obtained by routine lipid measurements. In this report we have investigated the relative predictive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72b4d0b7e8ce960e5f1376521d75f001
https://pubmed.ncbi.nlm.nih.gov/11114956
https://pubmed.ncbi.nlm.nih.gov/11114956
Autor:
B, MacKness, M I, Mackness, P N, Durrington, S, Arrol, A E, Evans, D, McMaster, J, Ferrières, J B, Ruidavets, N R, Williams, A N, Howard
Publikováno v:
European journal of clinical investigation. 30(1)
The rate of coronary heart disease is over three-fold greater in Belfast than in Toulouse and the excess risk cannot be totally explained by 'classical' risk factors such as total cholesterol, LDL-cholesterol, smoking, etc.The effect of the human ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d225fa2894e025dcc9fa8c7defd4fb1e
https://pubmed.ncbi.nlm.nih.gov/10619995
https://pubmed.ncbi.nlm.nih.gov/10619995
Publikováno v:
Diabetic medicine : a journal of the British Diabetic Association. 16(5)
To investigate the hypothesis that lipid peroxidation of both low-density lipoproteins (LDL) and high-density lipoproteins (HDL) is important in the development of atherosclerosis.We have investigated whether LDL and HDL from patients with Type 1 dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ceb72be32ad6a39c327ee40812ed6dc0
https://pubmed.ncbi.nlm.nih.gov/10342342
https://pubmed.ncbi.nlm.nih.gov/10342342
Publikováno v:
Clinical endocrinology. 49(2)
Low doses of androgen are used in women for the symptomatic treatment of sexual dysfunction and premenstrual syndrome (PMS). However, little is known about the long-term safety of androgen use in women. This study investigated the effects of low dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::65135dfb87f65ac53c51c089e6552e4b
https://pubmed.ncbi.nlm.nih.gov/9828899
https://pubmed.ncbi.nlm.nih.gov/9828899
Fetal and maternal lipoprotein metabolism in human pregnancy complicated by type I diabetes mellitus
Publikováno v:
The Journal of clinical endocrinology and metabolism. 83(5)
Serum lipid, apolipoprotein concentration, and lipoprotein composition were determined in maternal and umbilical venous cord blood at delivery by elective Cesarean section (CS) in 10 singleton, full-term pregnancies with maternal insulin-dependent di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3cacc04912fb5b4aa44419ce525f3fec
https://pubmed.ncbi.nlm.nih.gov/9589684
https://pubmed.ncbi.nlm.nih.gov/9589684
Publikováno v:
Diabetic medicine : a journal of the British Diabetic Association. 13(2)
We have examined cholesteryl ester transfer (CET) from HDL to low density and very low density lipoproteins (LDL and VLDL) and lecithin: cholesterol acyl transferase (LCAT) activity in plasma from 28 men with non-insulin-dependent diabetes mellitus (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3ac34e12d5d84d603024364a8625f80
https://pubmed.ncbi.nlm.nih.gov/8641118
https://pubmed.ncbi.nlm.nih.gov/8641118