Zobrazeno 1 - 10
of 76
pro vyhledávání: '"M. I. Koukourakis"'
Publikováno v:
Infectious Diseases in Obstetrics and Gynecology, Vol 2007 (2007)
Aims. To investigate the possible association of human papillomavirus (HPV) with endometrial hyperplasias and neoplasia. Does HPV play any role in the initiation or prognosis of endometrial adenocarcinomas? Methods. Twenty-five endometrial adenocarci
Externí odkaz:
https://doaj.org/article/bbc922a9dec542559b3f8e5454c36aa0
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1880
A method is described for the immunostaining of human prostate cancer biopsies for the autophagic marker LC3 and the lysosomal protein LAMP2A. Using this combination we can provide some information on autophagic flux, and specific patterns of stainin
Autor:
S Mavropoulou, Stamatia Pouliliou, Efthimios Sivridis, Marianthi Panteliadou, P S Chondrou, Alexandra Giatromanolaki, M I Koukourakis
Publikováno v:
British Journal of Cancer
Background: Radiotherapy provides high-cure rates in prostate cancer. Despite its overall slow clinical growth, high proliferation rates documented in a subset of tumours relate to poor radiotherapy outcome. This study examines the role of anaerobic
Autor:
D Laurent, M I Koukourakis, M. Shi, David Lebwohl, Adrian L. Harris, Gerold Meinhardt, Alexandra Giatromanolaki, Gunnar Folprecht, Efthimios Sivridis, Tanja Trarbach, K C Gatter, T Jalava
Publikováno v:
British Journal of Cancer
Background: Pharmacological inhibitors of vascular endothelial growth factor (VEGF) receptors, like vatalanib, have been tested in randomised trials (CONFIRM (Colorectal Oral Novel therapy For the Inhibition of Angiogenesis and Retarding of Metastase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ce239b53ec51d563057147c62894ad
https://doi.org/10.1038/bjc.2012.369
https://doi.org/10.1038/bjc.2012.369
Autor:
Efthimios Sivridis, Alexandra Giatromanolaki, M I Koukourakis, Alexandros Polychronidis, Adrian L. Harris, C. Simopoulos, K C Gatter
Aims To investigate the significance of the hypoxia inducible factors HIF-1α and HIF-2α in gallbladder adenocarcinomas and their relation to angiogenesis and to the expression of VEGF, an angiogenic factor transcriptionally regulated by HIFαs. Met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9299d4da73c83c70ce915c9cfabd2ec
https://doi.org/10.1002/jso.20443
https://doi.org/10.1002/jso.20443
Autor:
Adrian L. Harris, K C Gatter, Efthimios Sivridis, M I Koukourakis, Alexandra Giatromanolaki, I Papadopoulos
Publikováno v:
British Journal of Cancer
Thymidine phosphorylase is an angiogenic factor primarily expressed by cancer cells, stromal cells and tumour-associated macrophages in many human malignancies. These different types of thymidine phosphorylase-expressing cells, however, may have a di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9ebca1ba78f4c7d26f78c61069f549
https://ora.ox.ac.uk/objects/uuid:3545e920-0c5a-4df1-a93c-f08907bae63a
https://ora.ox.ac.uk/objects/uuid:3545e920-0c5a-4df1-a93c-f08907bae63a
Autor:
Al Harris, K C Gatter, Alexandra Giatromanolaki, Efthimios Sivridis, M I Koukourakis, Georgios Bougioukas, Vassilios Didilis
Publikováno v:
British Journal of Cancer
Lactate dehydrogenase-5 (LDH-5) catalyses the reversible transformation of pyruvate to lactate, having a principal position in the anaerobic cellular metabolism. Induction of LDH-5 occurs during hypoxia and LDH-5 transcription is directly regulated b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12caf7f7e03820133238ae9e5f99bca
https://ora.ox.ac.uk/objects/uuid:4a26dd7b-12c3-4968-b452-cdb01199014c
https://ora.ox.ac.uk/objects/uuid:4a26dd7b-12c3-4968-b452-cdb01199014c
Autor:
Efthimios Sivridis, Vassilios Danielidis, M I Koukourakis, V Tsakmaki, Alexandra Giatromanolaki
Publikováno v:
British Journal of Cancer
Background: Cancer stem cells (CSCs) tend to repopulate malignant tumours during radiotherapy and, therefore, prolongation of the overall treatment time may result in radiotherapy failure. Thus, an estimate of the number of CSCs in tumour biopsies ma
Publikováno v:
Journal of Clinical Pathology. 58:1033-1038
Background: Stroma frequently forms at sites of active tumour invasion, and may be important for tumour growth and progression. The term “stromatogenesis” is used to describe this unique process that involves host peritumorous fibroblasts and is
Autor:
Efthimios Sivridis, Constantinos Simopoulos, K C Gatter, M I Koukourakis, Alexandra Giatromanolaki, David A. Jackson, Adrian L. Harris
Publikováno v:
Journal of Clinical Pathology. 58:202-206
Aims/Methods: Normal and malignant pulmonary and endometrial tissues were analysed for lymphatic vessels to assess the process of lymphangiogenesis and its role at these sites, using specific immunostaining for LYVE-1 and the panendothelial marker CD