Zobrazeno 1 - 10
of 43
pro vyhledávání: '"M. I. Shakhparonov"'
Publikováno v:
Doklady Biochemistry and Biophysics. 508:21-24
Abstract Glioblastoma multiforme (GBM) is the most aggressive malignant brain tumor. One of the reasons for the resistance of GBM to treatment is the extreme heterogeneity of the tumor and, in particular, the presence of cancer stem cells (CSCs) in t
Publikováno v:
Doklady Biochemistry and Biophysics. 508:31-36
Abstract The interactome of paraoxonase-2 encoded by the PON2 gene was investigated. A cDNA library was screened using a yeast two-hybrid system to search for new proteins interacting with human PON2. Analysis of the identified candidates, along with
Autor:
Tatyana D. Larionova, N. V. Antipova, Marat S. Pavlyukov, M. I. Shakhparonov, T. F. Kovalenko
Publikováno v:
Acta Naturae
Among the many malignant neoplasms, glioblastoma (GBM) leads to one of the worst prognosis for patients and has an almost 100% recurrence rate. The only chemotherapeutic drug that is widely used for treating glioblastoma is temozolomide, a DNA alkyla
Autor:
Ksenia Anufrieva, Yury P Rubtsov, Victoria O. Shender, A. A. Gulin, Marat S. Pavlyukov, Tatiana F Kovalenko, Soniya Bastola, Alexander Potapov, Samvel K Gularyan, Yaroslav A. Latyshev, N. V. Antipova, M. I. Shakhparonov
Publikováno v:
Mol Cell Proteomics
Glioblastoma (GBM) is one of the most aggressive human cancers with a median survival of less than two years. A distinguishing pathological feature of GBM is a high degree of inter- and intratumoral heterogeneity. Intertumoral heterogeneity of GBM ha
Publikováno v:
Doklady. Biochemistry and biophysics. 503(1)
Glioblastoma (GBM) is considered one of the most aggressive human cancers. Earlier, our group have demonstrated that alternative RNA splicing plays an important role in the regulation of the GBM phenotype. To continue this study, we analyzed the type
Autor:
Maria A. Nikiforova, A. V. Volkov, M. I. Shakhparonov, Vladimir A. Gushchin, Andrei E. Siniavin, Tatyana D. Larionova, Marat S. Pavlyukov, Igor I. Babichenko, N. V. Antipova
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 23
International Journal of Molecular Sciences, Vol 21, Iss 9167, p 9167 (2020)
Volume 21
Issue 23
International Journal of Molecular Sciences, Vol 21, Iss 9167, p 9167 (2020)
In 2020 the world faced the pandemic of COVID-19 severe acute respiratory syndrome caused by a new type of coronavirus named SARS-CoV-2. To stop the spread of the disease, it is crucial to create molecular tools allowing the investigation, diagnoses
In 2020 the world faced the pandemic of COVID-19 - severe acute respiratory syndrome caused by a new type of coronavirus named SARS-CoV-2. To stop the spread of the disease, it is crucial to create molecular tools allowing to investigate, diagnose an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dbb1467864f8e89b39d0990c00d96e3
https://doi.org/10.1101/2020.08.29.272963
https://doi.org/10.1101/2020.08.29.272963
Autor:
N P Fadeeva, Ksenia Anufrieva, Soniya Bastola, V. O. Shender, N. V. Antipova, G. A. Stepanov, Marat S. Pavlyukov, M. I. Shakhparonov
Publikováno v:
Acta Naturae
In response to the wide variety of external and internal signals, mammalian cells undergo apoptosis, programmed cell death. Dysregulation of apoptosis is involved in multiple human diseases, including cancer, autoimmunity, and ischemic injuries. Two
Autor:
Soniya Bastola, Ichiro Nakano, M. I. Shakhparonov, Marat S. Pavlyukov, Victoria Shender, Tatyana D. Larionova
Publikováno v:
Neuro-oncology Advances
Glioblastoma (GBM) is an extremely heterogeneous tumor and its different regions are populated with phenotypically distinct types of cancer cells. However, it is still unclear how multiple GBM populations arise from the originally homogenous group of
Autor:
Vadim M. Govorun, Ivan Butenko, M. I. Shakhparonov, Marat S. Pavlyukov, Maria A. Lagarkova, Polina V Shnaider, Ksenia Anufrieva, Victoria Shender, Georgij Arapidi
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-18 (2018)
Genome Medicine
Genome Medicine
Background Abnormal pre-mRNA splicing regulation is common in cancer, but the effects of chemotherapy on this process remain unclear. Methods To evaluate the effect of chemotherapy on slicing regulation, we performed meta-analyses of previously publi