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Baseline serum levels of IgA anti-cyclic citrullinated protein antibodies in early rheumatoid arthritis predict radiographic progression after 11 years of treatment: a secondary analysis of the CIMESTRA study

Autor: EB Rasmussen, LS Thiele, K Stengaard-Pedersen, ML Hetland, K Hørslev-Petersen, P Junker, M Østergaard, AS Hansen, M Hvid, B Deleuran, SR Greisen

Publikováno v: Rasmussen, E B, Thiele, L S, Stengaard-Pedersen, K, Hetland, M L, Hørslev-Petersen, K, Junker, P, Østergaard, M, Hansen, A S, Hvid, M, Deleuran, B & Greisen, S R 2022, ' Baseline serum levels of IgA anti-cyclic citrullinated protein antibodies in early rheumatoid arthritis predict radiographic progression after 11 years of treatment-a secondary analysis of the CIMESTRA study ', Scandinavian Journal of Rheumatology . https://doi.org/10.1080/03009742.2022.2127245

Objective: Smoking and periodontitis are risk factors for developing rheumatoid arthritis (RA), suggesting a break of tolerance on mucosal surfaces. Immunoglobulin A (IgA) antibodies are part of the mucosal immune system. The dominant autoantibodies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c53aca7f259e08b7fd3e12dd6bc2062
https://pubmed.ncbi.nlm.nih.gov/36255383

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Increased synovial galectin-3 induce inflammatory fibroblast activation and osteoclastogenesis in patients with rheumatoid arthritis

Autor: MA Nielsen, D Køster, S Greisen, A Troldborg, K Stengaard-Pedersen, P Junker, K Hørslev-Petersen, ML Hetland, M Østergaard, M Hvid, H Leffler, TW Kragstrup, B Deleuran

Publikováno v: Nielsen, M A, Køster, D, Greisen, S, Troldborg, A, Stengaard-Pedersen, K, Junker, P, Hørslev-Petersen, K, Hetland, M L, Østergaard, M, Hvid, M, Leffler, H, Kragstrup, T W & Deleuran, B 2023, ' Increased synovial galectin-3 induce inflammatory fibroblast activation and osteoclastogenesis in patients with rheumatoid arthritis ', Scandinavian Journal of Rheumatology, vol. 52, no. 1, pp. 33-41 . https://doi.org/10.1080/03009742.2021.1992860
Nielsen, M A, Køster, D, Greisen, S, Troldborg, A, Stengaard-Pedersen, K, Junker, P, Hørslev-Petersen, K, Hetland, M L, Østergaard, M, Hvid, M, Leffler, H, Kragstrup, T W & Deleuran, B 2022, ' Increased synovial galectin-3 induce inflammatory fibroblast activation and osteoclastogenesis in patients with rheumatoid arthritis ', Scandinavian Journal of Rheumatology . https://doi.org/10.1080/03009742.2021.1992860

OBJECTIVE: Galectin-3 (Gal-3) has been suggested as a proinflammatory mediator in rheumatoid arthritis (RA). We aimed to study clinical and pathogenic aspects of Gal-3 in RA.METHOD: Plasma samples from healthy controls (n = 48) and patients with newl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b1cf6eb163f4225f5a8e9dfc201b08

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OP0106 SOLUBLE PD-1 PROMOTES LOCAL IL-17A PRODUCTION IN THE INFLAMED MICROENVIRONMENT IN SpA

Autor: E. Rasmussen, R. Østgård, M. Hvid, U. Syrbe, D. Poddubnyy, B. Deleuran, S. R. Greisen

Publikováno v: Annals of the Rheumatic Diseases. 81:70.3-70

BackgroundProgrammed death 1 (PD-1) is an immune checkpoint receptor expressed by activated T-cells. Activation of the PD-1 pathway reduces T cell activation and inflammation. Targeting PD-1 in cancer can result in autoimmune disease, which highlight

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::20e74256395992a267ca18e4521ca166
https://doi.org/10.1136/annrheumdis-2022-eular.705

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POS0415 PLASMA GALECTIN-9 IS ASSOCIATED WITH CLINICAL DISEASE ACTIVITY IN TREATMENT NAÏVE EARLY RHEUMATOID ARTHRITIS, UNAFFECTED BY DMARD TREATMENT, AND IN VITRO MODULATES THE SECRETION OF MCP-1 AND IL-6 IN RHEUMATOID ARTHRITIS SYNOVIAL FIBROBLASTS

Autor: M. A. Nielsen, D. Køster, K. Stengaard-Pedersen, P. Busson, P. Junker, K. Hørslev-Petersen, M. L. Hetland, M. Østergaard, M. Hvid, T. W. Kragstrup, B. Deleuran

Publikováno v: Annals of the Rheumatic Diseases. 81:462.1-463

BackgroundFibroblast-like synoviocytes (FLS) are pivotal mediators of rheumatoid synovitis expansive growth and invasiveness which respond insufficiently to disease-modifying antirheumatic drugs. Galectin-9 (Gal-9) is a lectin with well-conserved car

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e946054e8ce3960c457f198acde7d809
https://doi.org/10.1136/annrheumdis-2022-eular.1213

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Early Dynamic Versus Late Static Lymphoscintigraphy for the Identification of Sentinel Lymph Nodes in Breast Cancer

Autor: Sara Hasseriis, Helle M. Hvid, Susanne Skindhøj, Rikke D. Pedersen, Lars Jelstrup Petersen

Publikováno v: Petersen, L J, Pedersen, R D, Skindhøj, S, Hasseriis, S & Hvid, H M 2011, ' Early dynamic versus late static lymphoscintigraphy for the identification of sentinel lymph nodes in breast cancer ', Clinical Nuclear Medicine, vol. 36, no. 12, pp. 1098–1101 . https://doi.org/10.1097/RLU.0b013e31821a2aaf

PURPOSE Sentinel lymph node (SLN) biopsy is an established method for the identification of early breast cancer metastases. SLN lymphoscintigraphy is pivotal in many cases, but the diagnostic value of early dynamic versus late static imaging procedur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa97ba36e87e6f4b16efc707a8cfa89c
https://doi.org/10.1097/rlu.0b013e31821a2aaf

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