Zobrazeno 1 - 10
of 198
pro vyhledávání: '"M. Hunfeld"'
Publikováno v:
Resuscitation Plus, Vol 17, Iss , Pp 100563- (2024)
Long-term outcome studies after pediatric cardiac arrest (CA) are few. They require a CA registry and dedicated outcome teams. Learning about the long-term outcomes is very important for developing prognostication guidelines, improving post-cardiac c
Externí odkaz:
https://doaj.org/article/9c506bd9b3214876b0c0914c00350a2e
Autor:
Letao Li, Sebastiaan D. T. Sassen, Tim M. J. Ewoldt, Alan Abdulla, Nicole G. M. Hunfeld, Anouk E. Muller, Brenda C. M. de Winter, Henrik Endeman, Birgit C. P. Koch
Publikováno v:
Antibiotics, Vol 12, Iss 2, p 383 (2023)
The number of pharmacokinetic (PK) models of meropenem is increasing. However, the daily role of these PK models in the clinic remains unclear, especially for critically ill patients. Therefore, we evaluated the published meropenem models on real-wor
Externí odkaz:
https://doaj.org/article/aa2133f593ba423898dabeb780442696
Autor:
Alan Abdulla, Annemieke Dijkstra, Nicole G. M. Hunfeld, Henrik Endeman, Soma Bahmany, Tim M. J. Ewoldt, Anouk E. Muller, Teun van Gelder, Diederik Gommers, Birgit C. P. Koch
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-12 (2020)
Abstract Background Early and appropriate antibiotic dosing is associated with improved clinical outcomes in critically ill patients, yet target attainment remains a challenge. Traditional antibiotic dosing is not suitable in critically ill patients,
Externí odkaz:
https://doaj.org/article/0f154ec3e09242a69e716dee85ab5a45
Autor:
A. Abdulla, T. M. J. Ewoldt, N. G. M. Hunfeld, A. E. Muller, W. J. R. Rietdijk, S. Polinder, T. van Gelder, H. Endeman, B. C. P. Koch
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Critically ill patients undergo extensive physiological alterations that will have impact on antibiotic pharmacokinetics. Up to 60% of intensive care unit (ICU) patients meet the pharmacodynamic targets of beta-lactam antibiotics,
Externí odkaz:
https://doaj.org/article/86302601f60149f0a4ce50af1293c6c4
Publikováno v:
Critical Care Research and Practice, Vol 2022 (2022)
Background. Regarding sustainability in the intensive care unit (ICU), there is increasing interest in reducing material waste and avoiding unnecessary procedures. Therapeutic drug monitoring (TDM) of vancomycin, using a dedicated tube, is standard c
Externí odkaz:
https://doaj.org/article/b70aa91530374213bfa71a17221d40c4
Autor:
Florine A. Berger, Willem vanWeteringen, Heleen van derSijs, Nicole G. M. Hunfeld, Jeroen J. H. Bunge, Natasja M. S. deGroot, Patricia M. L. A. van denBemt, Teun vanGelder
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 6, Pp n/a-n/a (2021)
Abstract QTc interval prolongation is an adverse effect associated with the use of fluoroquinolones and macrolides. Ciprofloxacin and erythromycin are both frequently prescribed QTc‐prolonging drugs in critically ill patients. Critically ill patien
Externí odkaz:
https://doaj.org/article/5f37d38168b543ef8ddce277663a57a1
Autor:
Letao Li, Sebastiaan D. T. Sassen, Mathieu van der Jagt, Henrik Endeman, Birgit C. P. Koch, Nicole G. M. Hunfeld
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 549 (2022)
Haloperidol is considered the first-line treatment for delirium in critically ill patients. However, clinical evidence of efficacy is lacking and no pharmacokinetic studies have been performed in intensive care unit (ICU) patients. The aim of this st
Externí odkaz:
https://doaj.org/article/1d34a33f630044b28320dbe9e902a547
Autor:
Lorenzo G. R. Romano, Nicole G. M. Hunfeld, Marieke J. H. A. Kruip, Henrik Endeman, Tim Preijers
Publikováno v:
British Journal of Clinical Pharmacology, 89(5), 1617-1628. Wiley-Blackwell Publishing Ltd
Aims: Nadroparin is administered to COVID-19 intensive care unit (ICU) patients as thromboprophylaxis. Despite existing population pharmacokinetic (PK) models for nadroparin in literature, the population PK of nadroparin in COVID-19 ICU patients is u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551cf0ca5a8180df3eca6f71a04927d6
https://doi.org/10.1111/bcp.15634
https://doi.org/10.1111/bcp.15634
Autor:
Tim M. J. Ewoldt, Alan Abdulla, Wim J. R. Rietdijk, Anouk E. Muller, Brenda C. M. de Winter, Nicole G. M. Hunfeld, Ilse M. Purmer, Peter van Vliet, Evert-Jan Wils, Jasper Haringman, Annelies Draisma, Tom A. Rijpstra, Attila Karakus, Diederik Gommers, Henrik Endeman, Birgit C. P. Koch
Publikováno v:
Intensive Care Medicine, 48(12), 1760-1771. Springer-Verlag
PURPOSE: Individualising drug dosing using model-informed precision dosing (MIPD) of beta-lactam antibiotics and ciprofloxacin has been proposed as an alternative to standard dosing to optimise antibiotic efficacy in critically ill patients. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28aa6ee40e28707832669f6466335c8
http://www.scopus.com/inward/record.url?scp=85141693147&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85141693147&partnerID=8YFLogxK
Autor:
Zoran Trogrlic, Lisa Smit, Robert-Jan Osse, Huibert H Ponssen, Arjen J C Slooter, Nicole G M Hunfeld, Wim J R Rietdijk, M. van den Boogaard, A.J.B.W. Brouwers, J.A. Lens, B.J.M. van der Meer, H. Ponssen, F.J. Schoonderbeek, K.S. Simons, E. Berger, A. Bouman, M. Campo, D. van Duijn, H. Embden – van Donk, D. van de Graaf, E. Hoogendoorn, P. Ormskerk, N. Roovers, E. Toscano, A. Vileito, T. van Zuylen, C. Exler, E. van den Berg, J. van Meeteren, M. Koopmanschap, I. Nutma, E. Kuijper
Publikováno v:
BMJ Open, Vol 10, Iss 9 (2020)
Introduction Delirium in critically ill adults is associated with prolonged hospital stay, increased mortality and greater cognitive and functional decline. Current practice guideline recommendations advocate the use of non-pharmacological strategies
Externí odkaz:
https://doaj.org/article/d5b1d0870108471abc96d800db9b2f17