Zobrazeno 1 - 10
of 240
pro vyhledávání: '"M. Hummer"'
Autor:
Itzel Condado-Morales, Fabian Dingfelder, Isabel Waibel, Oliver M. Turnbull, Bhargav Patel, Zheng Cao, Jais Rose Bjelke, Susanne Nedergaard Grell, Anja Bennet, Alissa M. Hummer, Matthew I. J. Raybould, Charlotte M. Deane, Thomas Egebjerg, Nikolai Lorenzen, Paolo Arosio
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Engineered antibody formats, such as antibody fragments and bispecifics, have the potential to offer improved therapeutic efficacy compared to traditional full-length monoclonal antibodies (mAbs). However, the translation of these non-natural molecul
Externí odkaz:
https://doaj.org/article/902ae4a0e4394deeb9b5cd245a0a3c88
Antibody-antigen binding affinity lies at the heart of therapeutic antibody development: efficacy is guided by specific binding and control of affinity. Here we present Graphinity, an equivariant graph neural network architecture built directly from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a043171ece27c11118ff943fdd61051f
https://doi.org/10.1101/2023.05.17.541222
https://doi.org/10.1101/2023.05.17.541222
Publikováno v:
Bioinformatics
Motivation Monoclonal antibody (mAb) therapeutics are often produced from non-human sources (typically murine), and can therefore generate immunogenic responses in humans. Humanization procedures aim to produce antibody therapeutics that do not elici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32e1a852dc1b1536e6a9c9d51707965
https://doi.org/10.1093/bioinformatics/btab434
https://doi.org/10.1093/bioinformatics/btab434
Autor:
A. H. Birner, M. Hemetsberger, H. P. Dimai, Christian Muschitz, A. Hlava, Johannes Grillari, M. Hummer
Publikováno v:
Osteoporosis International
Summary Fragility fractures are a frequent and costly event. In Austria, 92,835 fragility fractures occurred in patients aged ≥ 50 years in 2018, accruing direct costs of > 157 million €. Due to demographic aging, the number of fragility fracture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6f4102edaa5421b8f2f7bfc9e8fee7
https://pubmed.ncbi.nlm.nih.gov/34622302
https://pubmed.ncbi.nlm.nih.gov/34622302
Autor:
Dan Li, Sean Mackay, Boro Dropulic, Stephen M. Hewitt, Rimas J. Orentas, Aarti Kolluri, Hongjia Yang, Mitchell Ho, Mingqian Feng, Daniel Abate-Daga, Qun Wang, Haiying Fu, Alissa M. Hummer, Zhijian Duan, Dina Schneider, Jin-Qiu Chen, Yi-Fan Zhang, Matthew D. Hall, Jing Zhou, Xiaoling Luo, Ling Su, Xiaolin Wu, Madeline B. Torres, Tim F. Greten, Hu Zhu, Nan Li, Josh Kramer
Publikováno v:
Gastroenterology
Background and Aims Glypican 3 (GPC3) is an oncofetal antigen involved in Wnt-dependent cell proliferation that is highly expressed in hepatocellular carcinoma (HCC). We investigated whether the functions of chimeric antigen receptors (CARs) that tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261fe0702784df06dfb33eec5101841c
https://pubmed.ncbi.nlm.nih.gov/33606993
https://pubmed.ncbi.nlm.nih.gov/33606993
Autor:
Hermann Detz, A. Amsuess, B. Lutzer, Ole Bethge, M. Hummer, Herbert Hutter, Emmerich Bertagnolli, C. Zimmermann, S. Simsek, Michael Stoeger-Pollach
Publikováno v:
ECS Journal of Solid State Science and Technology. 4:P387-P392
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3dfb752b47a3ad051f857f501c72def
https://doi.org/10.1149/2.0181509jss
https://doi.org/10.1149/2.0181509jss
Autor:
M. Hummer, W. Wolfgang Fleischhacker
Publikováno v:
Der Nervenarzt. 77:S77-S98
The management of schizophrenia patients remains one of the great challenges in psychiatry. Despite the undisputed effectiveness of antipsychotic drugs, patients and their physicians still face considerable difficulties mainly related to incomplete o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aba1d046e51c71a3e4b31846e666f66
https://doi.org/10.1007/s00115-006-2194-8
https://doi.org/10.1007/s00115-006-2194-8
Akademický článek
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Publikováno v:
Canadian Journal of Chemistry. 78:1445-1458
Equimolar amounts of trichlorovinylsilane (9), lithium-tert-butyl, and 1,3-enynes were reacted to yield the corresponding isomeric silacyclobutanes and silacyclobutenes competitively. As reaction pathway the mixture 9/tBuLi is discussed to give a sil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d120f0ab6d8b09881c335b5497d631c
https://doi.org/10.1139/v99-247
https://doi.org/10.1139/v99-247
Publikováno v:
IEEE Photonics Technology Letters. 21:36-38
We have fabricated continuous-wave GaInAsSb-AlGaAsSb distributed-feedback (DFB) lasers in the 2.8- mum range, using a DFB concept requiring no subsequent overgrowth steps, by defining first-order Cr-Bragg gratings laterally to a ridge waveguide. We h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54c9e57714908e5922678a64226ebbab
https://doi.org/10.1109/lpt.2008.2005846
https://doi.org/10.1109/lpt.2008.2005846