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Intrinsically disordered RNA-binding motifs cooperate to catalyze RNA folding and drive phase separation.

Autor: Niedner-Boblenz A; Institute of Structural Biology, Molecular Targets and Therapeutics Center, Helmholtz Munich, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.; Department of Anatomy and Cell Biology, Biomedical Center of the Ludwig-Maximilians University München, Großhaderner Str. 9, 82152 Planegg-Martinsried, Germany., Monecke T; Institute of Pharmaceutical Biotechnology, Ulm University, James-Franck-Ring N27, 89081 Ulm, Germany., Hennig J; Institute of Structural Biology, Molecular Targets and Therapeutics Center, Helmholtz Munich, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.; Department of Bioscience and Bavarian NMR Center, TUM School of Natural Sciences, Technical University of Munich, Lichtenbergstrasse 4, 85747 Garching, Germany.; Structural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL), Meyerhofstr. 1, 69117 Heidelberg, Germany.; Department of Biochemistry IV-Biophysical Chemistry, University of Bayreuth, Universitätsstraße 30 / BGI, 95447 Bayreuth, Germany., Klostermann M; Buchmann Institute for Molecular Life Sciences (BMLS) and Institute of Molecular Biosciences, Goethe University Frankfurt, Max-von-Laue-Str. 15, 60438 Frankfurt, Germany.; Theodor-Boveri-Institut für Biowissenschaften, Lehrstuhl für Bioinformatik, Biozentrum, Julius-Maximilians-Universität Würzburg, Am Hubland, 97074 Würzburg, Germany., Hofweber M; Department of Anatomy and Cell Biology, Biomedical Center of the Ludwig-Maximilians University München, Großhaderner Str. 9, 82152 Planegg-Martinsried, Germany., Davydova E; Institute of Structural Biology, Molecular Targets and Therapeutics Center, Helmholtz Munich, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany., Gerber AP; Department of Microbial Sciences, School of Biosciences, Faculty of Health and Medical Sciences, University of Surrey, Stag Hill Campus, 10AX01, Guildford GU2 7XH, UK., Anosova I; Institute of Structural Biology, Molecular Targets and Therapeutics Center, Helmholtz Munich, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.; Department of Bioscience and Bavarian NMR Center, TUM School of Natural Sciences, Technical University of Munich, Lichtenbergstrasse 4, 85747 Garching, Germany., Mayer W; Institute of Pharmaceutical Biotechnology, Ulm University, James-Franck-Ring N27, 89081 Ulm, Germany., Müller M; Institute of Structural Biology, Molecular Targets and Therapeutics Center, Helmholtz Munich, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.; Department of Molecular Biology, Biomedical Center of the Ludwig-Maximilians University München,Großhaderner Str. 9, 82152 Planegg-Martinsried, Germany., Heym RG; Institute of Structural Biology, Molecular Targets and Therapeutics Center, Helmholtz Munich, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany., Janowski R; Institute of Structural Biology, Molecular Targets and Therapeutics Center, Helmholtz Munich, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany., Paillart JC; IBMC, Architecture et Réactivité de l'ARN, Université de Strasbourg, CNRS, 2 allée Konrad Roentgen, 67000 Strasbourg, France., Dormann D; Department of Anatomy and Cell Biology, Biomedical Center of the Ludwig-Maximilians University München, Großhaderner Str. 9, 82152 Planegg-Martinsried, Germany.; Biocenter, Institute of Molecular Physiology, Johannes Gutenberg-Universität (JGU), Hanns-Hüsch-Weg 17, 55128Mainz, Germany.; Institute of Molecular Biology (IMB), Ackermannweg 4, 55128 Mainz, Germany., Zarnack K; Buchmann Institute for Molecular Life Sciences (BMLS) and Institute of Molecular Biosciences, Goethe University Frankfurt, Max-von-Laue-Str. 15, 60438 Frankfurt, Germany.; Theodor-Boveri-Institut für Biowissenschaften, Lehrstuhl für Bioinformatik, Biozentrum, Julius-Maximilians-Universität Würzburg, Am Hubland, 97074 Würzburg, Germany., Sattler M; Institute of Structural Biology, Molecular Targets and Therapeutics Center, Helmholtz Munich, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.; Department of Bioscience and Bavarian NMR Center, TUM School of Natural Sciences, Technical University of Munich, Lichtenbergstrasse 4, 85747 Garching, Germany., Niessing D; Institute of Structural Biology, Molecular Targets and Therapeutics Center, Helmholtz Munich, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.; Department of Anatomy and Cell Biology, Biomedical Center of the Ludwig-Maximilians University München, Großhaderner Str. 9, 82152 Planegg-Martinsried, Germany.; Institute of Pharmaceutical Biotechnology, Ulm University, James-Franck-Ring N27, 89081 Ulm, Germany.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 Nov 18. Date of Electronic Publication: 2024 Nov 18.