Zobrazeno 1 - 10
of 423
pro vyhledávání: '"M. Hedrick"'
Autor:
Philip A. May, Anna-Susan Marais, Wendy O. Kalberg, Marlene M. de Vries, David Buckley, Julie M. Hasken, Cudore L. Snell, Ronel Barnard Röhrs, Dixie M. Hedrick, Heidre Bezuidenhout, Lise Anthonissen, Erine Bröcker, Luther K. Robinson, Melanie A. Manning, H. Eugene Hoyme, Soraya Seedat, Charles D. H. Parry
Publikováno v:
Annals of Medicine, Vol 55, Iss 1, Pp 926-945 (2023)
AbstractBackground Pregnant women participated in multifaceted case management (MCM) to prevent Fetal Alcohol Spectrum Disorders (FASD).Methods Women recruited from antenatal clinics for a longitudinal child development study were screened for alcoho
Externí odkaz:
https://doaj.org/article/fdae073627504f54aafcd18ce99dc570
Autor:
Kevin D. Mlynek, Curtis R. Cline, Sergei S. Biryukov, Ronald G. Toothman, Beth A. Bachert, Christopher P. Klimko, Jennifer L. Shoe, Melissa Hunter, Zander M. Hedrick, Jennifer L. Dankmeyer, Sherry Mou, David P. Fetterer, Ju Qiu, Eric D. Lee, Christopher K. Cote, Qingmei Jia, Marcus A. Horwitz, Joel A. Bozue
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 19, Iss 3 (2023)
ABSTRACTFrancisella tularensis is one of the several biothreat agents for which a licensed vaccine is needed. To ensure vaccine protection is achieved across a range of virulent F. tularensis strains, we assembled and characterized a panel of F. tula
Externí odkaz:
https://doaj.org/article/0ace613ea2ce4951941639be362626b4
Autor:
Sergei S. Biryukov, Christopher K. Cote, Christopher P. Klimko, Jennifer L. Dankmeyer, Nathaniel O. Rill, Jennifer L. Shoe, Melissa Hunter, Zain Shamsuddin, Ivan Velez, Zander M. Hedrick, Raysa Rosario-Acevedo, Yuli Talyansky, Lindsey K. Schmidt, Caitlyn E. Orne, David P. Fetterer, Mary N. Burtnick, Paul J. Brett, Susan L. Welkos, David DeShazer
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Burkholderia pseudomallei and the closely related species, Burkholderia mallei, produce similar multifaceted diseases which range from rapidly fatal to protracted and chronic, and are a major cause of mortality in endemic regions. Besides causing nat
Externí odkaz:
https://doaj.org/article/ca916529189043a0a6727d77d964e0ef
Autor:
Zhiqian Li, Nimi Marcel, Sushil Devkota, Ankush Auradkar, Stephen M. Hedrick, Valentino M. Gantz, Ethan Bier
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
CRISPR-based genetic elements can copy themselves across host genomes. Here the authors introduce CopyCatcher, a gene-drive related system for detecting and quantifying somatic gene conversion events.
Externí odkaz:
https://doaj.org/article/b94ecd06f7bb42bcb6d8bcbcc6d0a9f1
Akademický článek
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Autor:
Alexander J Weitzel, Hannah A Grunwald, Ceri Weber, Rimma Levina, Valentino M Gantz, Stephen M Hedrick, Ethan Bier, Kimberly L Cooper
Publikováno v:
PLoS Biology, Vol 19, Iss 12, p e3001478 (2021)
Highly efficient gene conversion systems have the potential to facilitate the study of complex genetic traits using laboratory mice and, if implemented as a "gene drive," to limit loss of biodiversity and disease transmission caused by wild rodent po
Externí odkaz:
https://doaj.org/article/baaab7397acd4441888d4b328da69680
Publikováno v:
Health Communication. :1-11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47ffbc7bde393cc5b384c0cc02175276
https://doi.org/10.1080/10410236.2023.2174403
https://doi.org/10.1080/10410236.2023.2174403
Autor:
Daniel T. Utzschneider, Arnaud Delpoux, Dominik Wieland, Xin Huang, Chen-Yen Lai, Maike Hofmann, Robert Thimme, Stephen M. Hedrick
Publikováno v:
Cell Reports, Vol 22, Iss 13, Pp 3454-3467 (2018)
Summary: Immunity following an acutely resolved infection or the long-term equipoise of chronic viral infections often depends on the maintenance of antigen-specific CD8+ T cells, yet the ongoing transcriptional requirements of these cells remain unc
Externí odkaz:
https://doaj.org/article/8d00be06d5784495b315b6323a25c4e9
Publikováno v:
The Journal of Immunology. 209:1118-1127
In response to an intracellular infectious agent, the immune system produces a specific cellular response as well as a T cell–dependent Ab response. Precursor T cells differentiate into effector T cells, including Th1 cells, and T follicular helper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a43e8227cd1cd8b536c84ea3661ac7b
https://doi.org/10.4049/jimmunol.2100777
https://doi.org/10.4049/jimmunol.2100777
Autor:
Megan E. Grund, Eliza Kramarska, Soo Jeon Choi, Dudley H. McNitt, Christopher P. Klimko, Nathaniel O. Rill, Jennifer L. Dankmeyer, Jennifer L. Shoe, Melissa Hunter, David P. Fetterer, Zander M. Hedrick, Ivan Velez, Sergei S. Biryukov, Christopher K. Cote, Rita Berisio, Slawomir Lukomski
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1219 (2021)
Burkholderia pseudomallei is an infectious bacterium of clinical and biodefense concern, and is the causative agent of melioidosis. The mortality rate can reach up to 50% and affects 165,000 people per year; however, there is currently no vaccine ava
Externí odkaz:
https://doaj.org/article/f0325049872148c6b26d2abf44affa70