Phytoconstituents of Citrus limon (Lemon) as Potential Inhibitors Against Multi Targets of SARS‐CoV‐2 by Use of Molecular Modelling and In Vitro Determination Approaches.

Autor: Raman, Kannan¹ (AUTHOR), Kalirajan, Rajagopal¹ (AUTHOR) rkalirajan@jssuni.edu.in, Islam, Fahadul² (AUTHOR), Jupudi, Srikanth¹ (AUTHOR), Selvaraj, Divakar¹ (AUTHOR), Swaminathan, Gomathi¹ (AUTHOR), Singh, Laliteshwar Pratap³ (AUTHOR), Rana, Ritesh⁴ (AUTHOR), Akash, Shopnil² (AUTHOR), Islam, Md. Rezaul² (AUTHOR), Nainu, Firzan⁵ (AUTHOR), Emran, Talha Bin^2,6 (AUTHOR), Dawoud, Turki M.⁷ (AUTHOR), Bourhia, Mohammed⁸ (AUTHOR) bourhiamohammed@gmail.com, Dauelbait, Musaab⁹ (AUTHOR), Barua, Rashu¹⁰ (AUTHOR)

Publikováno v: ChemistryOpen. Oct2024, Vol. 13 Issue 10, p1-18. 18p.

Alpha-synuclein immunoreactivity of huntingtin polyglutamine aggregates in striatum and cortex of Huntington's disease patients and transgenic mouse models

Autor: Eva Mezey, Theresa A. Young, P. Hemachandra Reddy, Michael J. Brownstein, M H Polymeropoulos, Anindya Dehejia, Vinod Charles, Danilo A. Tagle

Publikováno v: Neuroscience Letters. 289:29-32

Polyglutamine expansions in proteins are implicated in at least eight inherited neurodegenerative disorders, including Huntington's disease. These mutant proteins can form aggregates within the nucleus and processes of neurons possibly due to misfold

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ecc73f8bc286f24a44c7975c46f031
https://doi.org/10.1016/s0304-3940(00)01247-7

Predisposition of Wolfram syndrome heterozygotes to psychiatric illness

Autor: M H Polymeropoulos, Ronnie Gorman Swift, Michael Swift, R Torres

Publikováno v: Molecular Psychiatry. 3:86-91

Identification of specific genes that predispose to psychiatric illness will lead to more precise psychiatric diagnosis and more effective treatment. Heterozygous carriers of genes for many autosomal recessive syndromes may be 1% or more of the gener

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d9dc2f4822a4b378f5f45ab5f861f0
https://doi.org/10.1038/sj.mp.4000344

Linkage of the locus for cerebral cavernous hemangiomas to human chromosome 7q in four families of Mexican-American descent

Autor: S. Basnet, J. Rubenstein, K. Lane, Robert F. Spetzler, M. H. Polymeropoulos, Daniele Rigamonti, Frank P.K. Hsu, Orest Hurko, H. Dietz

Publikováno v: Neurology. 48:752-757

Article abstract-Objective: To determine with greater precision the map location of the locus associated with familial cavernous hemangiomas. Background: Cavernous malformations of the brain are a significant cause of seizures, progressive or apoplec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8577503e39227d0642802ef835194aec
https://doi.org/10.1212/wnl.48.3.752

A sporadic case of male-limited precocious puberty has the same constitutively activating point mutation in luteinizing hormone/choriogonadotropin receptor gene as familial cases

Autor: Leonard D. Kohn, Koichi Yano, Gordon B. Cutler, A Okuno, A Hidaka, M H Polymeropoulos, Motoyasu Saji

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 79:1818-1823

Familial male-limited precocious puberty (FMPP) is an autosomal dominant disorder characterized by marked elevation of serum testosterone despite low levels of gonadotropin. Recently, a single point mutation in the LH/hCG receptor (LH/CGR) gene was f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec7b70e5bc71204ebd015bf8c3dfe400
https://doi.org/10.1210/jcem.79.6.7527413