Zobrazeno 1 - 10
of 25
pro vyhledávání: '"M. H. Karol"'
Publikováno v:
SAR and QSAR in Environmental Research. 16:273-285
Structure-activity relationship (SAR) models are recognized as powerful tools to predict the toxicologic potential of new or untested chemicals and also provide insight into possible mechanisms of toxicity. Models have been based on physicochemical a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9675f583d132d226389ea4d24d6f1e3a
https://doi.org/10.1080/10659360500036976
https://doi.org/10.1080/10659360500036976
Publikováno v:
Allergy. 50:48-54
RAST is routinely used to assess the presence of IgE antibodies against environmental allergens in the sera of symptomatic patients. With exposure to low-mol.-mass (chemical) allergens, RAST is also done, but the interpretation of results is more dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609b5499353001c9ab003adc598a0896
https://doi.org/10.1111/j.1398-9995.1995.tb02482.x
https://doi.org/10.1111/j.1398-9995.1995.tb02482.x
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 31(7)
Nearly 9 million individuals are exposed to agents in the workplace associated with asthma, and isocyanates represent the most common cause of occupationally induced asthma.Nonetheless, the immunological mechanisms responsible for isocyanate-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4c2d6cbc381764c00d0c93b987f1674f
https://pubmed.ncbi.nlm.nih.gov/11467998
https://pubmed.ncbi.nlm.nih.gov/11467998
Autor:
M H, Karol
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 31(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0e0236d54455bf2e065eb6470f005dd
https://pubmed.ncbi.nlm.nih.gov/11260145
https://pubmed.ncbi.nlm.nih.gov/11260145
Publikováno v:
Chemical research in toxicology. 10(4)
During our ongoing studies of the reactions of toluene diisocyanate (2,4- and 2,6-diisocyanatotoluene, TDI) in vivo, it became apparent that reactive form(s) of these diisocyanates reach(es) the circulatory system after passage through the respirator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e936302d6bd3a6556561c9dc37eae9c
https://pubmed.ncbi.nlm.nih.gov/9114980
https://pubmed.ncbi.nlm.nih.gov/9114980
Publikováno v:
New Trends in Allergy IV ISBN: 9783642643989
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::198c6a4d40fbcf0778636bf28d9c5e8c
https://doi.org/10.1007/978-3-642-60419-5_18
https://doi.org/10.1007/978-3-642-60419-5_18
Autor:
T. P. Campbell, M. H. Karol, D. J. Tollerud, Piero Maestrelli, Marina Saetta, Leonardo M. Fabbri, Ce Mapp
Publikováno v:
Scopus-Elsevier
Development of asthma after exposure to toluene diisocyanate (TDI) has been recognized in a variety of occupational settings. However, the pathogenesis of isocyanate-induced asthma remains controversial. In particular, the role of IgE in the developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0137e3c08f33eaefa70420197a2dc02d
http://hdl.handle.net/11577/129116
http://hdl.handle.net/11577/129116
Publikováno v:
Journal of toxicology and environmental health. 40(1)
Guinea pigs have been used extensively to model pulmonary hypersensitivity responses. Although guinea pigs produce mainly immunoglobulin G1 (IgG1) antibodies and humans produce IgE, both immunoglobulin classes have been shown to be regulated similarl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d8f6357ed0ab5be4247e5ef9be59ba5
https://pubmed.ncbi.nlm.nih.gov/8360939
https://pubmed.ncbi.nlm.nih.gov/8360939
Publikováno v:
Brain, behavior, and immunity. 7(2)
The effect of footshock stress on the induction phase of sensitization to keyhole limpet hemocyanin (KLH) introduced intraperitoneally was studied in adult male Sprague-Dawley rats. Rats were shocked at Days -1, 0, 1, and 3 relative to sensitization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56ef57104ddc3c69e0cb85b90eaf445
https://pubmed.ncbi.nlm.nih.gov/8347894
https://pubmed.ncbi.nlm.nih.gov/8347894
Autor:
M H, Karol
Publikováno v:
Annals of allergy. 66(6)
Isocyanates are highly reactive chemicals capable of causing a multitude of toxicologic effects including respiratory irritation, dermal irritation, contact sensitivity, and pulmonary hypersensitivity. In order to probe the mechanism(s) underlying th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5426998487f175023a0e1a4e3af04b31
https://pubmed.ncbi.nlm.nih.gov/1646579
https://pubmed.ncbi.nlm.nih.gov/1646579