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Publikováno v:
Journal of Neurochemistry. 26:779-783
—Gangliosides have been isolated from myelin obtained from three types of peripheral nerve: bovine spinal roots, bovine sciatic nerve and human sciatic nerve. Yields in most cases were 218–287 μg of lipid-bound sialic acid per g myelin, less tha
Conditioned appetitive stimulus increases extracellular dopamine in the nucleus accumbens of the rat
Publikováno v:
The European journal of neuroscience. 16(10)
This study used in vivo microdialysis to examine the release of dopamine (DA) in the nucleus accumbens (nAc) during the performance of a previously learned, signalled sucrose reward task, and during conditioning of a neutral tone stimulus to this rew
Publikováno v:
Effects of Nicotine on Biological Systems II ISBN: 9783034874472
A number of studies, principally from our laboratories, are reviewed, showing that acute systemic nicotine can improve performance both in patients with Alzheimer’s disease, in experimental animals bearing lesions to the forebrain cholinergic proje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d8bd7b126ef2ca23fd13de6d0ef38b1
https://doi.org/10.1007/978-3-0348-7445-8_44
https://doi.org/10.1007/978-3-0348-7445-8_44
Publikováno v:
Neuropharmacology. 28:43-47
The effects of some biologically active metabolites of tryptophan on the high pressure neurological syndrome (HPNS) were studied. Kynurenic acid, quinolinic acid, 5-hydroxytryptophan, kynurenine and 3-hydroxyanthranilic acid, at doses within the phys
Autor:
Alan J. Cross, I. N. Ferrier, Timothy J. Crow, S. J. Cooper, J. F. W. Deakin, Mark Poulter, J. A. Johnson, M. H. Joseph, R. Lofthouse, F. Owen
Publikováno v:
University of Manchester-PURE
In patients with Alzheimer-type dementia, in addition to the well-known losses of cholinergic neurones, there is evidence of degeneration of the noradrenergic and serotonergic innervation of the cerebral cortex. While noradrenergic and cholinergic re
Autor:
Alan J. Cross, G. J. Riley, M. H. Joseph, T. J. Crow, Harry F. Baker, Frank Owen, W. S. Killpack, Vivette Glover, A. Longden, R. Lofthouse
Publikováno v:
British Journal of Psychiatry. 134:249-256
SummaryDopamine and its metabolites homovanillic acid and dihydroxyphenylacetic acid, noradrenaline, serotonin and its metabolite 5-hydroxyindoleacetic acid, and tryptophan and its metabolite kynurenine have been assayed in 9 schizophrenic and 10 con
Autor:
M. H. Joseph, Alan J. Cross
Publikováno v:
Life Sciences. 28:499-505
A simple and sensitive method for the concurrent determination of the monoamine metabolites MHPG, DOPAC, HVA and 5HIAA in brain samples is described. After solvent extraction at acid pH, the metabolites are separated by HPLC on a C18 reversed phase c
Autor:
M. H. Joseph, P. C. Emson
Publikováno v:
Journal of Neurochemistry. 27:1495-1501
– The level of taurine around the epileptic focus induced by cobalt-gelatine pellet implantation into rat brain was found to be reduced at 8-11 days post-operation, the time of maximal spike activity in the electrocorticogram. It returned towards n
Publikováno v:
Journal of Neural Transmission. 58:193-204
Kynurenine, tryptophan and 5-hydroxyindoleacetic acid were measured in human lumbar and cisternal cerebrospinal fluid (CSF) taken during pneumoencephalography. The results do not support the hypothesis that any substantial part of the CSF kynurenine