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Autor:
David M Guimond, Nicholas R Cam, Nupura Hirve, Wei Duan, John D Lambris, Michael Croft, Constantine D Tsoukas
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63645 (2013)
The inducible T cell kinase (ITK) regulates type 2 (Th2) cytokines that provide defense against certain parasitic and bacterial infections and are involved in the pathogenesis of lung inflammation such as allergic asthma. Activation of ITK requires t
Externí odkaz:
https://doaj.org/article/edf470c0afbc4eea888e37cb6147f104
Autor:
Nupura Hirve, Roman M Levytskyy, Stephanie Rigaud, David M Guimond, Tomasz Zal, Karsten Sauer, Constantine D Tsoukas
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45158 (2012)
Binding of the membrane phospholipid phosphatidylinositol 3,4,5-trisphosphate (PIP(3)) to the Pleckstrin Homology (PH) domain of the Tec family protein tyrosine kinase, Inducible T cell Kinase (ITK), is critical for the recruitment of the kinase to t
Externí odkaz:
https://doaj.org/article/97cbf54ebbe84f86a9ad66d1ea411332
Publikováno v:
Bone marrow transplantation. 55(6)
Detectable in biopsies and body fluids, the measurement of a single or panels of microRNAs have been reported to be quite sensitive and specific for the prediction, diagnosis, and prognosis of many diseases. Interest in the use of microRNAs as biomar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb90bc8b96d22ab3f5a669f828dd0808
https://pubmed.ncbi.nlm.nih.gov/31796872
https://pubmed.ncbi.nlm.nih.gov/31796872
Autor:
S. Thiant, M. M. Moutuou, P. Laflamme, R. Sidi Boumedine, D. M. Leboeuf, L. Busque, J. Roy, M. Guimond
Publikováno v:
Blood Cancer Journal, Vol 10, Iss 11, Pp 1-1 (2020)
A correction to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c17d9a3e1226c5c06bf266b46d9ea2c4
http://link.springer.com/article/10.1038/s41408-020-00374-3
http://link.springer.com/article/10.1038/s41408-020-00374-3
Publikováno v:
Global Advances in Health and Medicine
The Building Interdisciplinary Research Careers in Women's Health (BIRCWH) program is a mentored institutional research career development program developed to support and foster the interdisciplinary research careers of men and women junior faculty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af92539fac0c414c84954e7a3ae0663
https://doi.org/10.7453/gahmj.2013.049
https://doi.org/10.7453/gahmj.2013.049
Publikováno v:
Journal of Family Violence. 27:165-175
Preliminary research suggests that child abuse is indirectly associated with female-perpetrated intimate partner violence via posttraumatic stress disorder (PTSD) symptoms and anger. To date, however, no known studies have investigated these relation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5467bc457941d8ec7412fcacd60d4a34
https://doi.org/10.1007/s10896-012-9415-7
https://doi.org/10.1007/s10896-012-9415-7
Autor:
Joel S. Milner, Christopher W. Dyslin, Valerie A. Stander, Julie L. Crouch, Patricia M. Martens, Jennifer M. Guimond, Mandy M. Rabenhorst, Cynthia J. Thomsen, Lex L. Merrill
Publikováno v:
MALTRATTAMENTO E ABUSO ALL'INFANZIA. :11-45
anche se la trasmissione intergenerazionale della violenza familiare č stata ben documentata, il meccanismo responsabile di questo effetto non č stato ancora completamente accertato. Il presente studio valuta se i sintomi traumatici mediano la rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a749fcf75ca9cb8707eb241438fec00
https://doi.org/10.3280/mal2011-001002
https://doi.org/10.3280/mal2011-001002
Autor:
David M. Guimond, John D. Lambris, Juris A. Grasis, Nicholas R. Cam, Krystal Herman, Paola Magotti, Constantine D. Tsoukas
Publikováno v:
Molecular and Cellular Biology. 30:3596-3609
In vitro data have suggested that activation of the inducible T-cell kinase (ITK) requires an interaction with the adaptor protein SLP-76. One means for this interaction involves binding of the ITK SH3 domain to the polyproline-rich (PR) region of SL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb326d88d2314eda761fa87aff3c29c
https://doi.org/10.1128/mcb.01657-09
https://doi.org/10.1128/mcb.01657-09
Autor:
Jennifer M. Guimond, Diana W. Bianchi, Dennis A. Twombly, Susan E. Taymans, Sarah Glavin, Catherine Y. Spong
Publikováno v:
JAMA Pediatrics. 172:226
Investing in the next generation of researchers is essential, as recently highlighted in the 21st Century Cures Act. From its inception, the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) has supported trainin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5a7ab11a1b08367eedfbe0d568fe82
https://doi.org/10.1001/jamapediatrics.2017.4305
https://doi.org/10.1001/jamapediatrics.2017.4305