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Defining the Global Research and Programmatic Agenda and Priority Actions for Voluntary Medical Male Circumcision for HIV Prevention

Autor: Megan E, Peck, Todd, Lucas, Katherine S, Ong, Jonathan M, Grund, Stephanie, Davis, Aisha, Yansaneh, Valerian L, Kiggundu, Anne G, Thomas, Kelly, Curran, Catharine, Laube, Maaya, Sundaram, Wole, Ameyan, Lycias, Zembe, Carlos, Toledo

Publikováno v: Current HIV/AIDS Reports. 19:537-547

Purpose of ReviewSince 2007, voluntary medical male circumcision (VMMC) programs have been associated with substantially reduced HIV incidence across 15 prioritized countries in Eastern and Southern Africa. Drawing on the programmatic experience of g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d78d5405c1a69fafab032c8f23f3790
https://doi.org/10.1007/s11904-022-00640-y

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Akademický článek

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Impact of hemolysis on multi-OMIC pancreatic biomarker discovery to derisk biomarker development in precision medicine studies

Autor: Richard Searfoss, Punit Shah, Kennedy Ofori-Mensa, Valerie Bussberg, Vladimir Tolstikov, Bennett Greenwood, Hongyan Li, Kris Richardson, Gregory M. Miller, Corinne DeCicco, Elder Granger, Leonardo O. Rodrigues, Eric M. Grund, A. James Moser, Rangaprasad Sarangarajan, Niven R. Narain, Michael A. Kiebish

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Scientific Reports

Cancer biomarker discovery is critically dependent on the integrity of biofluid and tissue samples acquired from study participants. Multi-omic profiling of candidate protein, lipid, and metabolite biomarkers is confounded by timing and fasting statu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238a13eecd31ba8fc65409926af1e469
https://doaj.org/article/ff0d3450a9874c839c54f477fb0fae21

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A qualitative study describing provider perspectives on the influence of external support on the quality of HIV and TB services at public health clinics in Ekurhuleni, South Africa

Autor: Fadzai Munedzimwe, Katherine Milazzo, Salome Charalambous, Jonathan M Grund, Thandi Chaane, Candice M Chetty-Makkan

Background: To combat the HIV epidemic in South Africa, stronger health systems are needed to maintain progress towards reaching the UNAIDS 95-95-95 goals. South Africa’s National Department of Health (NDoH) has supported various health systems str

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3cea717950675e0a421ac6133d310013
https://doi.org/10.21203/rs.3.rs-2669264/v1

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Development of an Open Source Energy Disaggregation Tool for the Home Automation Platform Home Assistant

Autor: Raphael M. Grund, Lena C. Altherr

In order to reduce energy consumption of homes, it is important to make transparent which devices consume how much energy. However, power consumption is often only monitored aggregated at the house energy meter. Disaggregating this power consumption

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b192b7d4846e128314bd79f9778fe8e
https://htwk-leipzig.qucosa.de/id/qucosa:83837

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Septin-5 and -7-IgGs: Neurologic, Serologic, and Pathophysiologic Characteristics

Publikováno v: Annals of neurology. 92(6)

We sought to determine clinical significance of neuronal septin autoimmunity and evaluate for potential IgG effects.Septin-IgGs were detected by indirect immunofluorescence assays (IFAs; mouse tissue and cell based) or Western blot. IgG binding to (a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e579fb34e82ca0aeb2c71a9c377f3fd
https://pubmed.ncbi.nlm.nih.gov/36053822

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High risk sexual behaviours associated with traditional beliefs about gender roles among men interested in medical male circumcision in South Africa

Autor: Matthew Price, Jonathan M Grund, Salome Charalambous, Mary H. Latka, Evans Muchiri, Candice M. Chetty-Makkan

Publikováno v: AIDS Research and Therapy, Vol 18, Iss 1, Pp 1-9 (2021)
AIDS Research and Therapy

Background Beliefs about gender roles and high-risk sexual behaviours underlie the human immunodeficiency virus (HIV) epidemic in South Africa. Yet, there is limited information on the relationships between beliefs about gender roles and risky sexual

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f6e90145d1be18896bb4fd1e07b836
https://doaj.org/article/9b98e716cf204438af5b666cbcdae33e

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Akademický článek

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Teriflunomide shifts the astrocytic bioenergetic profile from oxidative metabolism to glycolysis and attenuates TNFα-induced inflammatory responses

Autor: Parijat, Kabiraj, Ethan M, Grund, Benjamin D S, Clarkson, Renee K, Johnson, Reghann G, LaFrance-Corey, Claudia F, Lucchinetti, Charles L, Howe

Publikováno v: Scientific Reports. 12

Astrocytes utilize both glycolytic and mitochondrial pathways to power cellular processes that are vital to maintaining normal CNS functions. These cells also mount inflammatory and acute phase reactive programs in response to diverse stimuli. While

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2887392e8177677378fc38690a1c039f
https://doi.org/10.1038/s41598-022-07024-7

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