Zobrazeno 1 - 10
of 39
pro vyhledávání: '"M. Gregor Madej"'
Autor:
Algirdas Miksys, Lifei Fu, M. Gregor Madej, Duarte N. Guerreiro, Susann Kaltwasser, Maria Conway, Sema Ejder, Astrid Bruckmann, Jon Marles-Wright, Richard J. Lewis, Conor O’Byrne, Jan Pané-Farré, Christine Ziegler
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Cryo-EM structures of the stress-sensing complex in Listeria innocua reveal conformational changes that initiate the signaling response to environmental stress.
Externí odkaz:
https://doaj.org/article/faa9afa773db4d11bf6a756c291707a8
Autor:
Veronika Heinz, Wenke Jäckel, Susann Kaltwasser, Laura Cutugno, Patricia Bedrunka, Anica Graf, Alexander Reder, Stephan Michalik, Vishnu M. Dhople, M. Gregor Madej, Maria Conway, Marcus Lechner, Katharina Riedel, Gert Bange, Aoife Boyd, Uwe Völker, Richard J. Lewis, Jon Marles-Wright, Christine Ziegler, Jan Pané-Farré
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
A cryo-electron microscopy reconstruction of a stressosome complex from a Gram-negative bacterium, Vibrio vulnificus, reveals variations in subunit composition and symmetry, which could serve to adjust the activation threshold in the response to low
Externí odkaz:
https://doaj.org/article/0034be498cef4e58a23a52ceb08946ea
Autor:
Felix Grünberger, Robert Reichelt, Ingrid Waege, Verena Ned, Korbinian Bronner, Marcell Kaljanac, Nina Weber, Zubeir El Ahmad, Lena Knauss, M. Gregor Madej, Christine Ziegler, Dina Grohmann, Winfried Hausner
Publikováno v:
Frontiers in Microbiology, Vol 11 (2021)
Although copper is in many cases an essential micronutrient for cellular life, higher concentrations are toxic. Therefore, all living cells have developed strategies to maintain copper homeostasis. In this manuscript, we have analyzed the transcripto
Externí odkaz:
https://doaj.org/article/c9078bfab54341d7a97a59cb7ccc6bcc
Autor:
Florian Sure, Marko Bertog, Sara Afonso, Alexei Diakov, Ralf Rinke, M. Gregor Madej, Sabine Wittmann, Thomas Gramberg, Christoph Korbmacher, Alexandr V. Ilyaskin
The epithelial sodium channel (ENaC) is a heterotrimer consisting of α-, β-, and γ-subunits. Channel activation requires proteolytic release of inhibitory tracts from the extracellular domains of α-ENaC and γ-ENaC; however, the proteases involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1647ad897ede0e49595e59a2dbc68df
https://epub.uni-regensburg.de/52234/
https://epub.uni-regensburg.de/52234/
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156392 (2016)
Bacterial sugar symporters in the Major Facilitator Superfamily (MFS) use the H+ (and in a few cases Na+) electrochemical gradients to achieve active transport of sugar into the cell. Because a number of structures of MFS sugar symporters have been s
Externí odkaz:
https://doaj.org/article/1931cb7e20264ad9bc8500f26913829f
Publikováno v:
The Journal of Biological Chemistry
Bacterial transporters are difficult to study using conventional electrophysiology because of their low transport rates and the small size of bacterial cells. Here, we applied solid-supported membrane–based electrophysiology to derive kinetic param
Autor:
Tina Stumpp, Stefan Somlo, Magdalena M. Mair, Ralph Witzgall, Denise Schmied, Michael Schober, Christoph Korbmacher, Marion Kubitza, Uwe de Vries, Melanie Grosch, Markus Moser, Alexandr V. Ilyaskin, Kerstin N. Schmidt, Thaissa Dantas Pessoa, M. Gregor Madej, Karl Kunzelmann, Tobias Staudner, Helga Othmen, Katrin Brunner, Silke Haerteis, Larissa Osten, Christine Ziegler
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Mutations in the PKD2 gene cause autosomal-dominant polycystic kidney disease but the physiological role of polycystin-2, the protein product of PKD2, remains elusive. Polycystin-2 belongs to the transient receptor potential (TRP) family of non-selec
Autor:
Felix, Grünberger, Robert, Reichelt, Ingrid, Waege, Verena, Ned, Korbinian, Bronner, Marcell, Kaljanac, Nina, Weber, Zubeir, El Ahmad, Lena, Knauss, M Gregor, Madej, Christine, Ziegler, Dina, Grohmann, Winfried, Hausner
Publikováno v:
Frontiers in Microbiology
Although copper is in many cases an essential micronutrient for cellular life, higher concentrations are toxic. Therefore, all living cells have developed strategies to maintain copper homeostasis. In this manuscript, we have analyzed the transcripto
Autor:
Ana Filipa Santos, Seica, Cristina V, Iancu, Benedikt, Pfeilschifter, M Gregor, Madej, Jun-Yong, Choe, Petra, Hellwig
Publikováno v:
J Biol Chem
The Staphylococcus epidermidis glucose/H(+) symporter (GlcP(Se)) is a membrane transporter highly specific for glucose and a homolog of the human glucose transporters (GLUT, SLC2 family). Most GLUTs and their bacterial counterparts differ in the tran
Autor:
Christine Ziegler, M. Gregor Madej
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 470:213-225
Cryo-electron microscopy (cryo-EM) permits the determination of atomic protein structures by averaging large numbers of individual projection images recorded at cryogenic temperatures-a method termed single-particle analysis. The cryo-preservation tr