Zobrazeno 1 - 8
of 8
pro vyhledávání: '"M. Graça Lobo"'
Autor:
Aurora Barros-Barbosa, Paulo Correia-de-Sá, J. Miguel Cordeiro, M. Graça Lobo, Ângela Oliveira
Publikováno v:
Neurochemistry International. 112:81-95
γ-Aminobutyric acid (GABA) and glutamate (Glu) are the main inhibitory and excitatory neurotransmitters in the central nervous system (CNS), respectively. Fine tuning regulation of extracellular levels of these amino acids is essential for normal br
Autor:
Fátima Ferreirinha, M. Graça Lobo, Paulo Correia-de-Sá, Marina Mendes, Jean Sévigny, Ângela Oliveira, Julie Pelletier, J. Miguel Cordeiro, Rui Rangel, Agostinho Santos, Aurora Barros-Barbosa
Refractoriness to existing medications of up to 80 % of the patients with mesial temporal lobe epilepsy (MTLE) prompts for finding new antiepileptic drug targets. The adenosine A2A receptor emerges as an interesting pharmacological target since its e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff198f045815514e5c9ce27e604b7c6
https://europepmc.org/articles/PMC5124012/
https://europepmc.org/articles/PMC5124012/
Autor:
Rui Rangel, Agostinho Santos, J. Miguel Cordeiro, Fátima Ferreirinha, Sónia Guerra-Gomes, Aurora Barros-Barbosa, Ana L. Fonseca, M. Graça Lobo, Paulo Correia-de-Sá
Publikováno v:
Epilepsia. 57(1)
Summary Objective Thirty percent of patients with epilepsy are refractory to medication. The majority of these patients have mesial temporal lobe epilepsy (MTLE). This prompts for new pharmacologic targets, like ATP-mediated signaling pathways, since
Publikováno v:
Synapse. 49:77-88
Nicotinic receptor (nAChR) subtypes involved in pre- and postjunctional actions underlying tetanic fade were studied in rat phrenic-nerve hemidiaphragms. We investigated the ability of subtype-specific nAChR antagonists to depress nerve-evoked contra
Publikováno v:
Neurochemical Research. 28:1591-1595
To evaluate if endogenous extracellular adenosine influences sodium channel activity in nerve terminals, we investigated how manipulations of extracellular adenosine levels influence 22Na uptake by rat brain synaptosomes stimulated with veratridine (
Publikováno v:
European journal of pharmacology. 544(1-3)
Nifedipine has a high incidence of neurologic adverse reactions as compared with other dihydropyridine Cav1 (L-type) channel blockers used for treating cardiovascular diseases. The mechanism mediating neuronal excitation by nifedipine is still in deb
Publikováno v:
Synapse (New York, N.Y.). 49(2)
Nicotinic receptor (nAChR) subtypes involved in pre- and postjunctional actions underlying tetanic fade were studied in rat phrenic-nerve hemidiaphragms. We investigated the ability of subtype-specific nAChR antagonists to depress nerve-evoked contra
Publikováno v:
Synapse; Aug2003, Vol. 49 Issue 2, p77-88, 12p