Zobrazeno 1 - 10
of 24
pro vyhledávání: '"M. Gordian Adam"'
Autor:
Qu Tian, M. Gordian Adam, Enrique Ozcariz, Giovanna Fantoni, Nader M. Shehadeh, Lisa M. Turek, Victoria L. Collingham, Mary Kaileh, Ruin Moaddel, Luigi Ferrucci
Publikováno v:
Metabolites, Vol 13, Iss 5, p 591 (2023)
As one of the OMICS in systems biology, metabolomics defines the metabolome and simultaneously quantifies numerous metabolites that are final or intermediate products and effectors of upstream biological processes. Metabolomics provides accurate info
Externí odkaz:
https://doaj.org/article/346c60fa9aba44c7b85fce58c02c9c0b
Autor:
Yoko M. Ambrosini, Sebastian Neuber, Dana Borcherding, Yeon-Jung Seo, Sergi Segarra, Barbara Glanemann, Oliver A. Garden, Udo Müller, M. Gordian Adam, Viet Dang, David Borts, Todd Atherly, Auriel A. Willette, Albert Jergens, Jonathan P. Mochel, Karin Allenspach
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2020)
Canine inflammatory bowel disease (IBD) is a chronic, immunologically mediated intestinal disorder, resulting from the complex interaction of genetic, environmental and immune factors. Hydrolyzed diets are used in dogs with food-responsive diarrhea (
Externí odkaz:
https://doaj.org/article/ab78f57642524467868c52fd236b6a35
Autor:
Péter Hegyi, Andrea Szentesi, Katalin Márta, László Czakó, Noémi Zádori, Dóra Illés, Emese Ivány, Gábor Holzinger, Klára Kosár, M Gordian Adam, Beate Kamlage, Gábor Zsóri, Máté Tajti, Márk M Svébis, Viktor Horváth, Ilona Oláh, Szilárd Váncsa, Bálint Czakó
Publikováno v:
BMJ Open, Vol 10, Iss 11 (2020)
Introduction Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis with an overall 5-year survival of approximately 8%. The success in reducing the mortality rate of PDAC is related to the discovery of new therapeutic agents, and to a signif
Externí odkaz:
https://doaj.org/article/a8d362cf0d2e4a23b7a712e1e28c92ee
Autor:
Ujjwal M. Mahajan, Bettina Oehrle, Simon Sirtl, Ahmed Alnatsha, Elisabetta Goni, Ivonne Regel, Georg Beyer, Marlies Vornhülz, Jakob Vielhauer, Ansgar Chromik, Markus Bahra, Fritz Klein, Waldemar Uhl, Tim Fahlbusch, Marius Distler, Jürgen Weitz, Robert Grützmann, Christian Pilarsky, Frank Ulrich Weiss, M. Gordian Adam, John P. Neoptolemos, Holger Kalthoff, Roland Rad, Nicole Christiansen, Bianca Bethan, Beate Kamlage, Markus M. Lerch, Julia Mayerle
Publikováno v:
Gastroenterology. 163:1407-1422
Pancreatic ductal adenocarcinoma cancer (PDAC) is a highly lethal malignancy requiring efficient detection when the primary tumor is still resectable. We previously developed the MxPancreasScore comprising 9 analytes and serum carbohydrate antigen 19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150dcc51e3c382b44d1ab094ac49cf29
https://doi.org/10.1053/j.gastro.2022.07.047
https://doi.org/10.1053/j.gastro.2022.07.047
Autor:
Fabian Tetzlaff, M Gordian Adam, Anja Feldner, Iris Moll, Amitai Menuchin, Juan Rodriguez-Vita, David Sprinzak, Andreas Fischer
Publikováno v:
eLife, Vol 7 (2018)
Angiogenesis is coordinated by VEGF and Notch signaling. DLL4-induced Notch signaling inhibits tip cell formation and vessel branching. To ensure proper Notch signaling, receptors and ligands are clustered at adherens junctions. However, little is kn
Externí odkaz:
https://doaj.org/article/8679a42049a0422cafe8c98b6d9b4cb0
Autor:
Markus M. Lerch, M Gordian Adam, Christian Pilarsky, Georg Beyer, Nicole Christiansen, Julia Mayerle, Marcus Bahra, Robert Grützmann, Ujjwal M. Mahajan, Frank Ulrich Weiss, Fritz Klein, Beate Kamlage, Ansgar M. Chromik, Waldemar Uhl, Tim Fahlbusch, Marius Distler
Publikováno v:
Gut
ObjectiveChronic pancreatitis (CP) is a fibroinflammatory syndrome leading to organ dysfunction, chronic pain, an increased risk for pancreatic cancer and considerable morbidity. Due to a lack of specific biomarkers, diagnosis is based on symptoms an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a8411eaf16ad554f400538749313120
http://europepmc.org/articles/PMC8515121
http://europepmc.org/articles/PMC8515121
Autor:
Katalin Márta, M Gordian Adam, Dóra Illés, Bálint L Czakó, László Czakó, Péter Hegyi, Beate Kamlage, V Horvath, Máté Tajti, Márk M. Svébis, Ilona Oláh, Gábor Holzinger, Gábor Zsóri, Andrea Szentesi, Klára Kosár, Noémi Zádori, Emese Ivány, Szilárd Váncsa
Publikováno v:
BMJ Open
BMJ Open, Vol 10, Iss 11 (2020)
BMJ Open, Vol 10, Iss 11 (2020)
IntroductionPancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis with an overall 5-year survival of approximately 8%. The success in reducing the mortality rate of PDAC is related to the discovery of new therapeutic agents, and to a signifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51f2151fee3646e9afc5784d97353c05
http://europepmc.org/articles/PMC7678370
http://europepmc.org/articles/PMC7678370
Autor:
Sven S Liebler, Anja Feldner, M Gordian Adam, Thomas Korff, Hellmut G Augustin, Andreas Fischer
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53074 (2012)
The Delta-Notch pathway is a signal exchanger between adjacent cells to regulate numerous differentiation steps during embryonic development. Blood vessel formation by sprouting angiogenesis requires high expression of the Notch ligand DLL4 in the le
Externí odkaz:
https://doaj.org/article/32dfe7b923cd4cf9abaed49702edcb53
Autor:
Andreas Fischer, Eva-Maria Weis, M Gordian Adam, Fabian Tetzlaff, Joycelyn Wüstehube-Lausch, Ralph Klose, Chio Oka, Michael Ehrmann, Iris Moll
Publikováno v:
Oncogene. 37:4260-4272
The serine protease HTRA1 is involved in several vascular diseases and its expression is often deregulated in cancer. We aimed at identifying how HTRA1 in the vasculature affects tumor growth. Here we report that silencing of HTRA1 in cultured endoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5541b4dfa8437d05db0026d3d46745d
https://doi.org/10.1038/s41388-018-0258-4
https://doi.org/10.1038/s41388-018-0258-4
Autor:
Tobias Bäuerle, Fabian Tetzlaff, Anja Feldner, Andreas Fischer, Thomas Korff, M Gordian Adam, Hartwig Wolburg, Andreas von Deimling, Horst Schroten, Felix Sahm, Hiroshi Ishikawa, Dorde Komljenovic, Iris Moll, Ilse Hofmann
Publikováno v:
EMBO Molecular Medicine
Hydrocephalus is a common congenital anomaly. LCAM1 and MPDZ (MUPP1) are the only known human gene loci associated with non‐syndromic hydrocephalus. To investigate functions of the tight junction‐associated protein Mpdz, we generated mouse models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1907f961f85dec1ab5d978c2296212e9
https://doi.org/10.15252/emmm.201606430
https://doi.org/10.15252/emmm.201606430