Zobrazeno 1 - 10
of 279
pro vyhledávání: '"M. Gooding"'
Autor:
Kunihiko Aizawa, Alun D. Hughes, Francesco Casanova, Kim M. Gooding, Phillip E. Gates, David M. Mawson, Jennifer Williams, Isabel Goncalves, Jan Nilsson, Faisel Khan, Helen M. Colhoun, Carlo Palombo, Kim H. Parker, Angela C. Shore
Publikováno v:
ESC Heart Failure, Vol 11, Iss 5, Pp 3290-3298 (2024)
Abstract Aims Parameters derived from reservoir‐excess pressure analysis have been demonstrated to predict cardiovascular events. Thus, altered reservoir‐excess pressure parameters could have a detrimental effect on highly‐perfused organs like
Externí odkaz:
https://doaj.org/article/90221f9627714e60b5164d980c6f572e
Autor:
Om Prakash Dwivedi, Karina Barreiro, Annemari Käräjämäki, Erkka Valo, Anil K. Giri, Rashmi B. Prasad, Rishi Das Roy, Lena M. Thorn, Antti Rannikko, Harry Holthöfer, Kim M. Gooding, Steven Sourbron, Denis Delic, Maria F. Gomez, Per-Henrik Groop, Tiinamaija Tuomi, Carol Forsblom, Leif Groop, Maija Puhka
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106686- (2023)
Summary: Urinary extracellular vesicles (uEV) are a largely unexplored source of kidney-derived mRNAs with potential to serve as a liquid kidney biopsy. We assessed ∼200 uEV mRNA samples from clinical studies by genome-wide sequencing to discover m
Externí odkaz:
https://doaj.org/article/5b53c14dd8ee490b811a4f2dffd31175
Autor:
Kim M. Gooding, Chrysta Lienczewski, Massimo Papale, Niina Koivuviita, Marlena Maziarz, Anna-Maria Dutius Andersson, Kanishka Sharma, Paola Pontrelli, Alberto Garcia Hernandez, Julie Bailey, Kay Tobin, Virva Saunavaara, Anna Zetterqvist, David Shelley, Irvin Teh, Claire Ball, Sapna Puppala, Mark Ibberson, Anil Karihaloo, Kaj Metsärinne, Rosamonde E. Banks, Peter S. Gilmour, Michael Mansfield, Mark Gilchrist, Dick de Zeeuw, Hiddo J. L. Heerspink, Pirjo Nuutila, Matthias Kretzler, Matthew Welberry Smith, Loreto Gesualdo, Dennis Andress, Nicolas Grenier, Angela C. Shore, Maria F. Gomez, Steven Sourbron, for the BEAt-DKD consortium
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Diabetic kidney disease (DKD) remains one of the leading causes of premature death in diabetes. DKD is classified on albuminuria and reduced kidney function (estimated glomerular filtration rate (eGFR)) but these have modest value
Externí odkaz:
https://doaj.org/article/e94cbf7fb6ec48ce9d18b5b1e307048f
Autor:
Kunihiko Aizawa, Alun D. Hughes, Francesco Casanova, Phillip E. Gates, David M. Mawson, Kim M. Gooding, Mark Gilchrist, Isabel Goncalves, Jan Nilsson, Faisel Khan, Helen M. Colhoun, Carlo Palombo, Kim H. Parker, Angela C Shore
Publikováno v:
Hypertension. 79:2364-2372
Background: Arterial hemodynamic parameters derived from reservoir-excess pressure analysis exhibit prognostic utility. Reservoir-excess pressure analysis may provide useful information about an influence of altered hemodynamics on target organ such
Autor:
F. Casanova, D. D. Adingupu, F. Adams, K. M. Gooding, H. C. Looker, K. Aizawa, F. Dove, S. Elyas, J. J. F. Belch, P. E. Gates, R. C. Littleford, M. Gilchrist, H. M. Colhoun, A. C. Shore, F. Khan, W. D. Strain
Publikováno v:
Cardiovascular Diabetology, Vol 16, Iss 1, Pp 1-11 (2017)
Abstract Background Good glycaemic control in type 2 diabetes (T2DM) protects the microcirculation. Current guidelines suggest glycaemic targets be relaxed in advanced diabetes. We explored whether disease duration or pre-existing macrovascular compl
Externí odkaz:
https://doaj.org/article/fa3ba5c4c84d4c1aa8248f75dd5ba348
Publikováno v:
Practical Laboratory Medicine, Vol 15, Iss , Pp - (2019)
Background: Increasing albumin to creatinine ratio (ACR) within the normal range is a risk factor for cardiovascular disease in the general population. Clinical and epidemiological studies often store urine samples for long durations prior to ACR ass
Externí odkaz:
https://doaj.org/article/fee915cd2bed42c2acbe997b25152381
Autor:
Kunihiko Aizawa, Francesco Casanova, David M. Mawson, Kim M. Gooding, W. David Strain, Phillip E. Gates, Gerd Östling, Faisel Khan, Helen M. Colhoun, Carlo Palombo, Kim H. Parker, Jan Nilsson, Angela C. Shore, Alun D. Hughes
Publikováno v:
Artery Research, Vol 24 (2018)
Background: Central haemodynamic parameters derived from reservoir pressure analysis (RPA-parameters) exhibit prognostic utility. Alterations in reservoir function could have an unfavourable influence on target organs, such as the kidneys. We determi
Externí odkaz:
https://doaj.org/article/a4607fbe2d4a472797443fdfb62bf869
Autor:
Kunihiko, Aizawa, Phillip E, Gates, David M, Mawson, Salim, Elyas, Francesco, Casanova, Kim M, Gooding, Damilola D, Adingupu, W David, Strain, Angela C, Shore
Publikováno v:
Journal of Hypertension. 40:658-665
Different methods to measure carotid-femoral pulse wave velocity (CFPWV) may affect the measurements obtained and influence the association between CFPWV, cardiovascular risk factors and biomarkers of subclinical vascular health. The estimation of di
Autor:
D. Balfour, D. Boukerroui, Y. McQuinlan, R. Baggs, J. Turner, M. Battye, P. Looney, W. van Elmpt, A. Dekker, M. Gooding
Publikováno v:
Radiotherapy and Oncology. 170:S41-S43
Autor:
W. David Strain, Francesco Casanova, Jessica Tyrrell, Faisel Khan, Samuel E. Jones, Angela C. Shore, Kim M. Gooding, Beaumont Rn, Hanieh Yaghootkar, Andrew T. Hattersley, Timothy M. Frayling, Kunihiko Aizawa, Andrew R. Wood
Publikováno v:
Diabetes. 69:1072-1082
Urinary albumin-to-creatinine ratio (ACR) is a marker of diabetic nephropathy and microvascular damage. Metabolic-related traits are observationally associated with ACR, but their causal role is uncertain. Here, we confirmed ACR as a marker of microv