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pro vyhledávání: '"M. González-Rubio"'
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Akademický článek
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Publikováno v:
Medicine - Programa de Formación Médica Continuada Acreditado. 10:3830-3836
Autor:
Manuel Rodríguez-Puyol, M. González-Rubio, Piedad Ruiz-Torres, Javier Lucio, Diego Rodríguez-Puyol
Publikováno v:
Free Radical Biology and Medicine. 22:49-56
The mechanisms responsible for age-related glomerular sclerosis (GS) have not been clearly identified. The present experiments were aimed at assessing the importance of the oxidant/antioxidant balance in the early stages of this process. For this pur
Autor:
P. Ruiz Torres, Manuel Rodríguez-Puyol, M. González-Rubio, Diego Rodríguez-Puyol, F. J. Lucio-Cazaña
Publikováno v:
Geriatric Nephrology and Urology. 4:161-164
The present work deals with the hypothesis that probucol, through its antioxidant properties, may be a useful tool in the prevention of age-related glomerular sclerosis. Fifteen month-old male Sprague-Dawley rats were fedad libitum during three month
Publikováno v:
Biochemical and Biophysical Research Communications. 195:1057-1062
The present experiments were designed to analyze the ability of somatostatin to modulate the proliferation of cultured rat mesangial cells. In the absence of fetal calf serum, somatostatin stimulated cell proliferation in a dose-dependent manner. In
Autor:
Manuel Rodríguez-Puyol, Carmen García-Escribano, Diego Rodríguez-Puyol, M. González-Rubio, M L Díez-Marqués
Publikováno v:
Kidney International. 43(2):324-333
Somatostatin antagonizes angiotensin II effects on mesangial cell contraction and glomerular filtration. The effects of somatostatin (ST) on the regulation of the glomerular filtration rate have not been extensively studied. The present experiments w
Autor:
L, Gandía, R M, Alvarez, J M, Hernández-Guijo, J M, González-Rubio, R, de Pascual, J, Rojo, L, Tapia
Publikováno v:
Revista de neurologia. 42(8)
Among the numerous pathophysiological theories that attempt to explain the development of Alzheimer's disease (AD) there are two facts that stand out above the rest: on the one hand, the formation of neurofibrillary tangles inside cells and, on the o
Autor:
L González-Santiago, Manuel Rodríguez-Puyol, Diego Rodríguez-Puyol, J.A. Ruiz-Ginés, M. González-Rubio, Susana López-Ongil
Publikováno v:
Journal of cardiovascular pharmacology. 35(1)
The effects of reactive oxygen species (ROS) on different cellular types are variable. In some conditions they can be harmful metabolites, but they can also act as intracellular messengers that are able to activate different transcription factors. Ba
Autor:
M. González-Rubio, Manuel Rodríguez-Puyol, I. Arribas, Carmen García-Escribano, M L Díez-Marqués, Diego Rodríguez-Puyol, Martínez-Onsurbe P
Publikováno v:
Clinical science (London, England : 1979). 85(5)
1. The present study was designed to determine the changes in renal function in two models of experimental pancreatitis in rats, in an attempt to assess the possible pathogenic role of reactive oxygen species and to elucidate a possible therapeutic r