Zobrazeno 1 - 10
of 361
pro vyhledávání: '"M. Gibbins"'
Autor:
M. Gibbins, A. J. Kavanagh
Publikováno v:
Geoscientific Instrumentation, Methods and Data Systems, Vol 9, Pp 223-238 (2020)
The mesosphere is one of the most difficult parts of the atmosphere to sample; it is too high for balloon measurements and too low for in situ satellites. Consequently, there is a reliance on remote sensing (either from the ground or from space) to d
Externí odkaz:
https://doaj.org/article/f8f361b7fa0048bb8abd44994d49bf7f
Autor:
Joanne L. Mitchell, Dalia Khan, Rekha H. Rana, Neline Kriek, Amanda J. Unsworth, Tanya Sage, Alexander P. Bye, Michael Laffan, Susan Shapiro, Anjan Thakurta, Henri Grech, Karthik Ramasamy, Jonathan M. Gibbins
Publikováno v:
Platelets, Vol 34, Iss 1 (2023)
Multiple myeloma (MM) and its precursor states, smoldering myeloma (SM) and monoclonal gammopathy of undetermined significance (MGUS) are associated with increased incidence of thrombosis, however the cause of this is unknown. Lenalidomide treatment
Externí odkaz:
https://doaj.org/article/ed6b8d9969824f01bca243003c003438
Autor:
Chukiat Tantiwong, Joanne L. Dunster, Rachel Cavill, Michael G. Tomlinson, Christoph Wierling, Johan W. M. Heemskerk, Jonathan M. Gibbins
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Receptor diffusion plays an essential role in cellular signalling via the plasma membrane microenvironment and receptor interactions, but the regulation is not well understood. To aid in understanding of the key determinants of receptor diff
Externí odkaz:
https://doaj.org/article/2abb3eaafda6408294a30fc4910406b0
Autor:
Isabella Provenzale, Ilaria De Simone, Jonathan M. Gibbins, Johan W. M. Heemskerk, Paola E. J. van der Meijden, Chris I. Jones
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13352 (2023)
Proteoglycans form a heterogeneous family of proteins with covalently bound sulfated glycosaminoglycans. The extracellular matrix proteoglycan perlecan has been proposed to bind to the platelet- and megakaryocyte-specific receptor G6bB, co-regulating
Externí odkaz:
https://doaj.org/article/ef5f950331604834bdd420ccce4c5ba3
Autor:
Alexander P. Bye, Neline Kriek, Tanya Sage, Suzannah J. Rawlings, Catherine Prodger, Murali Kesavan, Charlotte Lees, Stephen Booth, Louise G. Cowen, Kirsty Shefferd, Michael J. Desborough, Jonathan M. Gibbins, Toby A. Eyre
Publikováno v:
Haematologica, Vol 108, Iss 5 (2022)
Externí odkaz:
https://doaj.org/article/91084de43c7345ffaefe97d67355137d
Publikováno v:
Platelets, Vol 32, Iss 7, Pp 888-894 (2021)
Connexins are a family of gap junction forming proteins widely expressed by mammalian cells. They assemble into hexameric hemichannels, which can either function independently or dock with opposing hemichannels on apposite cells, forming a gap juncti
Externí odkaz:
https://doaj.org/article/4ae5aca6e5a54d468fc0719f435e1db1
Publikováno v:
Platelets, Vol 32, Iss 6, Pp 761-769 (2021)
While current oral antiplatelet therapies benefit many patients, they deregulate the hemostatic balance leaving patients at risk of systemic side-effects such as hemorrhage. Dual antiplatelet treatment is the standard approach, combining aspirin with
Externí odkaz:
https://doaj.org/article/c9f34a90bab14c4fb9c20081fac32b70
Autor:
Sahithi J. Kuravi, Niaz S. Ahmed, Kirk A. Taylor, Emily M. Capes, Alex Bye, Amanda J. Unsworth, Jonathan M. Gibbins, Nicholas Pugh
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11689 (2023)
Zinc (Zn2+) is released by platelets during a hemostatic response to injury. Extracellular zinc ([Zn2+]o) initiates platelet activation following influx into the platelet cytosol. However, the mechanisms that permit Zn2+ influx are unknown. Fluctuati
Externí odkaz:
https://doaj.org/article/d04651147f4546c5b5a1b43159500bfc
Autor:
Jacob Ranjbar, Wanjiku Njoroge, Jonathan M. Gibbins, Paul Roach, Ying Yang, Alan G. S. Harper
Publikováno v:
Gels, Vol 9, Iss 6, p 477 (2023)
Current in vitro thrombosis models utilise simplistic 2D surfaces coated with purified components of the subendothelial matrix. The lack of a realistic humanised model has led to greater study of thrombus formation in in vivo tests in animals. Here w
Externí odkaz:
https://doaj.org/article/c0ae940eef0c494291826dc3e8a3c484
Publikováno v:
Platelets, Vol 32, Iss 3, Pp 368-377 (2021)
Vascular complications resulting from atherosclerosis development are a major cause of death. Reactive oxygen species (ROS) are produced by platelets during activation, and have been demonstrated to positively regulate platelet activatory responses.
Externí odkaz:
https://doaj.org/article/3e247de1207a4a1e88103fc271d45ea6