The contemporary significance of Framingham risk factors

Autor: Barbra E. Backus, Benjamin M. Gerretsen

Publikováno v: European Journal of Emergency Medicine, 28(3), 167-168. Lippincott Williams & Wilkins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d7c7b0e2c4d29dfab228e5ddbbf4a8
https://doi.org/10.1097/MEJ.0000000000000824

Complete ablation of small squamous cell carcinoma xenografts with186Re-labeled monoclonal antibody E48

Autor: Gerard W. M. Visser, Marijke van Walsum, G. B. Snow, M. Gerretsen, Ruud H. Brakenhoff, Guus van Dongen

Publikováno v: Cell Biophysics, 24-25(1-3), 135-142. Humana Press
Gerretsen, M, Visser, G W M, Brakenhoff, R H, van Walsum, M, Snow, G B & van Dongen, G A M S 1994, ' Complete ablation of small squamous cell carcinoma xenografts with186Re-labeled monoclonal antibody E48 ', Cell Biophysics, vol. 24-25, no. 1-3, pp. 135-142 . https://doi.org/10.1007/BF02789224

In previous studies we have shown that in mice bearing head and neck squamous cell carcinoma (HNSCC) xenografts, radioimmunotherapy (RIT) with186Re-labeled MAb E48 resulted in complete regressions in one-third of the tumors (followup >150 d). MAb E48

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b371ae7bba2d833dd802d4267324e01c
https://doi.org/10.1007/bf02789224

Radioimmunotherapy of human head and neck squamous cell carcinoma xenografts with 131I-labelled monoclonal antibody E48 IgG

Autor: B. J. M. Braakhuis, M. Gerretsen, Ad H. G. J. Schrijvers, C. J. L. M. Meijer, M. van Walsum, G. B. Snow, G.A.M.S. (Guus) van Dongen, Jasper J. Quak

Publikováno v: Gerretsen, M, Schrijvers, A H G J, Van Walsum, M, Braakhuis, B J M, Quak, J J, Meijer, C, Snow, G B & Van Dongen, G A M S 1992, ' Radioimmunotherapy of human head and neck squamous cell carcinoma xenografts with 131 i-labelled monoclonal antibody e48 igg ', British Journal of Cancer, vol. 66, no. 3, pp. 496-502 . https://doi.org/10.1038/bjc.1992.302
British Journal of Cancer
British Journal of Cancer, 66(3), 496-502. Nature Publishing Group

Monoclonal antibody (MAb) E48 reacts with a 22 kD antigen exclusively expressed in squamous and transitional epithelia and their neoplastic counterparts. Radiolabelled with99mTc, MAb E48 is capable of targeting metastatic and recurrent disease in pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f41dccb9ed0b148bb63acbcc5d9daa
https://doi.org/10.1038/bjc.1992.302

Detection of Squamous Cell Carcinoma Xenografts in Nude Mice by Radiolabeled Monoclonal Antibody E48

Autor: M. Gerretsen, Jasper J. Quak, Gordan B. Snow, Chris J.L.M. Meijer, Guus A.M.S. van Dongen, Ad H. G. J. Schrijvers

Publikováno v: Quak, J J, Gerretsen, M, Schrijvers, A H G J, Meijer, C J L M, Van Dongen, G A M S & Snow, G B 1991, ' Detection of Squamous Cell Carcinoma Xenografts in Nude Mice by Radiolabeled Monoclonal Antibody E48 ', Archives of Otolaryngology--Head and Neck Surgery, vol. 117, no. 11, pp. 1287-1291 . https://doi.org/10.1001/archotol.1991.01870230103017
Archives of Otolaryngology--Head and Neck Surgery, 117(11), 1287-1291. American Medical Association

We recently produced the monoclonal antibody E48 as a specific reagent for squamous cell carcinomas. In our ongoing investigations to use E48 for clinical tumor detection and therapy, fundamental aspects of the antigen have to be elucidated and pract

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619a100f73b09d6862d0633c33ba8f7b
https://doi.org/10.1001/archotol.1991.01870230103017

Superior localisation and imaging of radiolabelled monoclonal antibody E48 F(ab')2 fragment in xenografts of human squamous cell carcinoma of the head and neck and of the vulva as compared to monoclonal antibody E48 IgG

Autor: M. Gerretsen, Jasper J. Quak, C. J. L. M. Meijer, J. S. Suh, G.A.M.S. (Guus) van Dongen, G. B. Snow, M. Van Walsum

Publikováno v: British Journal of Cancer
British Journal of Cancer, 63(1), 37-44. Nature Publishing Group
Gerretsen, M, Quak, J J, Suh, J S, Van Walsum, M, Meijer, C J L M, Snow, G B & Van Dongen, G A M S 1991, ' Superior localisation and imaging of radiolabelled monoclonal antibody e48 f(ab') 2 fragment in xenografts of human squamous cell carcinoma of the head and neck and of the vulva as compared to monoclonal antibody e48 igg ', British Journal of Cancer, vol. 63, no. 1, pp. 37-44 . https://doi.org/10.1038/bjc.1991.9

Monoclonal antibody (MAb) E48 and its F(ab')2 fragment, radiolabelled with1311, were tested for tumour localisation and imaging in nude mice bearing a squamous cell carcinoma xenograft line derived from a head and neck carcinoma (HNX-HN) or from a vu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc24eab894f3cb8c0b18d2137c3fbe6c
http://europepmc.org/articles/PMC1971635